Santa Cruz Vacation Packages 2025/2026

Search vacation packages deals in Santa Cruz's top destinations

Santa Cruz

Vacations

Top Santa Cruz hotels deals

Ibis Santa Cruz DE LA Sierra

AVENIDA CRISTOBAL DE MENDOZA Santa Cruz

$35 nightly

$35 total

Dec 5 - Dec 6

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and airport shuttle. Free self parking, a coffee shop, and a snack bar/deli are also offered.

Pet friendly

Parking included

Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23 Santa Cruz Santa Cruz

$111 nightly

$111 total

Nov 28 - Nov 29

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.

Pool

Spa

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ave. San Martin, #455 Santa Cruz

$131 nightly

$131 total

Dec 10 - Dec 11

A full-service spa, 2 restaurants, and a hot tub are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

Sun Hotel

Av. Banzer Km 13 Santa Cruz Santa Cruz

$90 nightly

$90 total

Nov 28 - Nov 29

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Hot Tub

TRYP by Wyndham Santa Cruz

Av. San Martin, Calle 9 Este Santa Cruz

$69 nightly

$69 total

Dec 1 - Dec 2

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and free perks like buffet breakfast and free self parking. There's a sauna on site, and a 24-hour front desk and a terrace are also provided.

Pool

Breakfast included

Hotel Las Américas

Calle 21 de Mayo esq, Seoane N 356 Santa Cruz Santa Cruz Department

Free Cancellation

Reserve now, pay when you stay

$35 nightly

$35 total

Nov 21 - Nov 22

This hotel features a restaurant, a coffee shop, and free WiFi in public areas. Enjoy the free buffet breakfast each morning. A communal living room is provided and the front desk is staffed around-the-clock.

Breakfast included

Free WiFi

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Plaza 24 de Septiembre

4.5/5(26 reviews)

Learn about the local history of Santa Cruz when you spend time at Plaza 24 de Septiembre. While in the area, you can find time to visit its shops.

San Lorenzo Cathedral

4.5/5(15 reviews)

After visiting San Lorenzo Cathedral, make a plan to see the other sights and activities in Santa Cruz. While in the area, you can find time to visit its shops.

Ventura Mall

4.5/5(28 reviews)

During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.

Photos of local treasures

Browse Santa Cruz vacation photos for more inspiration

Lake Titicaca which includes general coastal views and a park

Lake Titicaca showing general coastal views

San Lorenzo Cathedral showing heritage elements, a church or cathedral and heritage architecture

Strait of Tiquina showing a bay or harbor and a lake or waterhole

San Lorenzo Cathedral which includes a church or cathedral, heritage architecture and heritage elements

Frequently asked questions

How much are vacation packages to Santa Cruz?

Spoil yourself with an unforgettable experience in Santa Cruz with a vacation package starting at just . Organizing your flights, tours and hotels through Travelocity is simple. And even better, our package deals will leave you with more savings for loads of fun activities.

Where can I get the best vacation package deals for Santa Cruz?

Travelocity is here to help you find an awesome Santa Cruz package deal. With 400 air carriers and 1,000,000 properties across the globe, you're sure to be able to put together the perfect itinerary.

Why should I purchase my Santa Cruz vacation bundle with Travelocity?

With top-quality service, 24/7 support and some of the most incredible getaways around, you'll never wander alone. And if you find a lower price, we'll match it. That's our Price Match Guarantee.

Will I save money on my Santa Cruz car rental if I book it with a hotel or flight?

Definitely. And our Santa Cruz vacation packages are the perfect way to do it. In only a few clicks you can save money and time by bundling your bookings. Collect the keys to your rental car and feel the freedom of the open road. Looking for things to do? Add a few tours to your package and save on those too.

Which airport is best for Santa Cruz?

Most Santa Cruz vacationers land at Viru Viru Intl. Airport (VVI).

What is there to do in Santa Cruz?

Santa Cruz has hidden gems at every turn, but make sure you see Ventura Mall and Guembe Biocenter while you're here. These two attractions shouldn't be missed.

Where to stay in Santa Cruz: Best areas for travelers

WarnesWarnes: Stay at the Los Jazmines Hotel Resort or the Terramia Resort and you'll be well taken care of. While you'll find a lot of awesome sights here, Warnes Plaza is one thing you can't miss. Make sure it's high on your sightseeing list!
Samaipata: Plan ahead so you can see all of this bustling destination. Fort Samaipata, Zoologico el refugio and Zoo el Refugio should be at the top of your bucket list. If excellent service and a good night's sleep are your main priorities, the Hotel Casablanca, the Hotel Casablanca Samaipata and the El Pueblito Hotel Boutique are stays to check out.
San Jose de Chiquitos: Santa Cruz is packed with popular sights, like Church of the Jesuit Mission of St. Joseph. Spend some time exploring this unique attraction before returning to the comfy surrounds of the Hotel Misiones de Chiquitos. Looking for more choices around town? The La Villa Chiquitana is also well-frequented by visitors.