Book Hotels in Panacea, FL
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Panacea hotels
Your Private Slice of the Forgotten Coast—Steps to Sand
Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
"Thank you being right in the beach was awesome."
Reviewed on Nov 14, 2025
Hideaway Beach Cottage on waterfront with amazing views.
Panacea FL
This cottage features a garden, laundry facilities, and barbecue grills.
"Property was good with the exception of yard, too many downed limbs…..no fault of owners, awful storm came thru"
Reviewed on Jul 27, 2026
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Alligator Point FL
$1,999 nightly
The price is $2,188 total per night from Aug 16 to Aug 17
$2,188 total
Aug 16 - Aug 17
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
"The house was perfect for our family, especially my mom who has trouble walking. The elevator worked perfectly, the boardwalk was short and close to the ocean. She and my dad loved sitting on the deck and watching us all on the beach. Communication was great, including updates on the tropical storm. ..."
Reviewed on Jul 25, 2026
Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations
Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
"We had a wonderful stay at this beachfront home! Being just steps from the Gulf made our vacation so relaxing and enjoyable. The covered porches and easy beach access were perfect. There was no need to haul heavy beach chairs or wrestle with umbrellas—just walk out the door and everything you need ..."
Reviewed on Jul 25, 2026
Secluded Florida Beach Bungalow BEST OF BOTH WORLDS BEACH TIME & FISHING TIME!!
Panacea FL
This vacation home features a garden, laundry facilities, and barbecue grills.
"We love the Spotted Grouper! We have returned for several years. The cottage is cozy with so many amenities—washer/dryer, beach wagon, great supply of towels. Booking is so easy and Sheree is a marvelous host."
Reviewed on Jul 27, 2026
NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!
Panacea FL
A hot tub is featured at this vacation home, along with laundry facilities and barbecue grills.
"Fantastic views of the water! Right on the beach! The house was immaculately done! The rooms were big especially the master bedroom! Kitchen had everything and more than needed! Can’t say enough of how much fun we had at this very well put together luxury accommodation!!! Beds were exceptional! Would ..."
Reviewed on Jul 18, 2026
Lighthouse- enjoy the water, bask in the view
Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
"So convenient to the beach"
Reviewed on Jul 26, 2026
The Panacea Motel
1545 Coastal Hwy Panacea FL
$119 nightly
The price is $133 total per night from Jul 30 to Jul 31
$133 total
Jul 30 - Jul 31
Total with taxes and fees
Stay at this motel in Panacea. Enjoy free WiFi, free parking, and hiking/biking on site. Popular attractions Panacea Springs and Woolley Park are located ...
"The apartment we rented was very clean, and beautifully decorated. The staff was very helpful, friendly, and responsive to our needs."
Reviewed on Jun 27, 2026
Coastal Getaway on canal-steps to the beach
Panacea FL
This vacation home features a garden, laundry facilities, and barbecue grills.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Panacea hotel reviews by fellow wanderers
Secluded Florida Beach Bungalow BEST OF BOTH WORLDS BEACH TIME & FISHING TIME!!
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"We love the Spotted Grouper! We have returned for several years. The cottage is cozy with so many amenities—washer/dryer, beach wagon, great supply of towels. Booking is so easy and Sheree is a marvelous host."
A verified traveler stayed at Secluded Florida Beach Bungalow BEST OF BOTH WORLDS BEACH TIME & FISHING TIME!!
Explore More Ways to Travel with Travelocity
- Hotels near Donald L Tucker Civic Center
- Hotels near Florida A&M University
- Hotels near Florida State Capitol Building
- Hotels near Florida State University
- Hotels in Ochlockonee Bay
- Hotels near Ochlockonee River State Park
- Cabins in Panacea
- Condos in Panacea
- Aparthotels in Panacea
- Guesthouses in Panacea
- AWESOME VIEW On Private Gulf of Mexico Beach Majestic Views
- CONDO Water front bay breeze fishing paradise and family friendly 2 bedroom
- Bayfront Condo with Boat Slip
- Bayside Retreat Panacea FL Bay Front Dock 2 Large Porches No Pets Wifi
- Beach in Panacea
- Beachfront Alligator Point Vacation Rental
- BEACHFRONT Turtles Nest Delight in Bald-Alligator Point with Private Beach
- Best deal at Alligator Point
- Alligator Point Old Florida Beachfront Cottage
- Enchanted Cottage Beachfront Charming Retreat by the Sea
- Historical in Panacea
- Legasea Old Florida Beachfront Charm with Two Screen Porches Sleeps 7
- Oceanview in Panacea
- Petfriendly in Panacea
- SALT AIR AND SERENDIPITY Unit B
- Sardegna- pool dock home by Mashes Sands Beach
- Shifting Sands Private Beach Front 3 Bd 2 Bath sleeps 8
- The Panacea Motel
- Pelican Perch
- Secluded Florida Beach Bungalow BEST OF BOTH WORLDS BEACH TIME & FISHING TIME
- Motels in Panacea
- Privatevacationhomes in Panacea
- Hotels in Quincy
- Condos in Saint Teresa
- Cottages in Saint Teresa
- Hotels in Saint Teresa
- Motels in Saint Teresa
- Cabins in Sopchoppy
- Hotels in Sopchoppy
- Beach in St George Island
- Buccaneer Inn
- Hotels in St George Island
- Hotels in St Marks
- Hotels near St Marks Lighthouse
- Hotels near St Marks National Wildlife Refuge
- Aparthotels in Tallahassee
- Budget in Tallahassee
- Kitchenette in Tallahassee
- Loyalty Inn Tallahassee
- Luxury in Tallahassee
- Motel 6 Tallahassee Fl - Downtown
- Petfriendly in Tallahassee
- The Lodge At Wakulla Springs
- Hotels in Tallahassee
- Hotels near Tallahassee Fl
- Hotels near Tallahassee Memorial Medical Center
- Hotels in Wakulla Beach
- Cabins in Wakulla County
- Hotels in Wakulla Springs
- Hotels near Wakulla Springs State Park
- Hotels in Woodville
- Privatevacationhomes in Dog Island
- Beach in Wakulla County
- Motels in Crawfordville
- Hotels in Crawfordville
- Petfriendly in Crawfordville
- Golf in Crawfordville
- Beach in Crawfordville
- Aparthotels in Crawfordville
- Cottages in Crawfordville
- Condos in Crawfordville
- Cabins in Crawfordville
- Apartments in Crawfordville
- Hotels near Cascades Park
- Hotels in Carrabelle
- Franklin Inn
- Hotels near Bobby Bowden Field At Doak Campbell Stadium
- Hotels near Bald Point State Park
- Hotels near Apalachicola National Forest
- Hotels in Apalachicola
- Privatevacationhomes in Alligator Point
- Motels in Alligator Point
- Hotels in Alligator Point
- Condos in Alligator Point
- Flights from Tallahassee Fl
- Flights from Fort Lauderdale (FLL) to Tallahassee (TLH)
- Flights from Orlando (MCO) to Tallahassee (TLH)
- Flights from Miami (MIA) to Tallahassee (TLH)
- Flights from West Palm Beach (PBI) to Tallahassee (TLH)
- Flights from Tampa (TPA) to Tallahassee (TLH)
- Flights to Tallahassee
- Flights to Saint Teresa
- Flights to Panacea
