Book Hotels in Keowee, SC

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Keowee hotels

Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson
Free WiFi in public areas is available at this cottage. Take advantage of the free self parking.
Opens in a new windowWooded Cottage - 3 Mi to Clemson University
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St, Clemson, SC
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $210 total per night from Sep 29 to Sep 30
$210 total
Sep 29 - Sep 30
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
"Excellent everything!"

Reviewed on Sep 19, 2025

Opens in a new windowThe Shepherd Hotel Downtown Clemson
Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson

2.5 out of 5
13050 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $122 total per night from Oct 5 to Oct 6
$122 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"What I liked was the customer service Alexa gave me. Had me sign up for Hilton Rewards program too since she mentioned it. No extra blankets in the room. The stay was excellent. Definitely recommend if in the Clemson area."

Reviewed on Sep 3, 2025

Opens in a new windowTru by Hilton Seneca Clemson
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Sep 27 to Sep 28
$135 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
"Great place to stay while visiting our Tiger!"

Reviewed on Sep 20, 2025

Opens in a new windowLakeside Lodge Clemson
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $108 total per night from Sep 28 to Sep 29
$108 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Beautiful facility with indoor balconi"

Reviewed on Sep 16, 2025

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Oct 10 to Oct 11
$101 total
Oct 10 - Oct 11
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Very good value for this hotel considering its location near Clemson's downtown. Comfortable beds."

Reviewed on Sep 15, 2025

Opens in a new windowComfort Inn & Suites Clemson - University Area
Inn @ Clemson

Inn @ Clemson

2.5 out of 5
1303 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $103 total per night from Oct 2 to Oct 3
$103 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Good location"

Reviewed on Sep 20, 2025

Opens in a new windowInn @ Clemson
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd, Seneca, SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Oct 5 to Oct 6
$93 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Convenient"

Reviewed on Sep 21, 2025

Opens in a new windowQuality Inn Seneca Clemson Area US-123
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd, Anderson, SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Sep 29 to Sep 30
$66 total
Sep 29 - Sep 30
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Friendly faces, cozy rooms—couldn’t ask for more Great vibes here! Would happily stay again."

Reviewed on Sep 20, 2025

Opens in a new windowDays Inn by Wyndham Anderson
Don't see what you're looking for?
See all available properties in Keowee
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Keowee?
From well-thought-out amenities to larger rooms, kid-friendly hotels are equipped with features that can help transform a regular family vacation into an awesome one. These Keowee properties make traveling with your youngsters a breeze: Your entourage will love staying at The Clemson Cottage | 3.6mi to Football Stadium. A playground and animal viewing activities are among the things that help make this place a favorite. Alternatively, spend your evenings in Keowee at Lake Hartwell/ Clemson condo- perfect game day retreat. Make the most of a firepit, free WiFi and more here.
Where can I find cheap hotels in Keowee?
At Travelocity you'll find really nice hotels in Keowee at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Keowee rather than in Keowee. We may find you even better rates, too.
How do I find the best Keowee hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Keowee then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Keowee?
The cheapest hotel in Keowee is $66. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Keowee?
There are 1,383 hotels in Keowee on Travelocity.
What are the best hotels in Keowee?
Keowee has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Keowee for you!
When is the best time to visit Keowee?
If you want the joy of a fun-filled trip in peak season, visit Keowee during February, July and November. If you'd prefer the peace of off-season, book a stay during quieter months, such as August, September and December.
When is the cheapest time to stay in Keowee?
Based on historic data is usually the cheapest month to visit Keowee. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Keowee?
There are multiple hotels in Keowee that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Keowee. We have plenty of kid-friendly hotels in Keowee to choose from on Travelocity!
Why book a hotel in Keowee through Travelocity?
Because we have the top hotels in Keowee! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Keowee on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Keowee hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity