Book Hotels in Keowee, SC
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Top Keowee hotels

The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
$219 nightly
The price is $243 total per night from Mar 22 to Mar 23
$243 total
Mar 22 - Mar 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
Excellent stay, I highly recommend! Accommodations, location, overall vibe, great food and drinks!
Reviewed on Mar 9, 2026

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
$109 nightly
The price is $120 total per night from Mar 11 to Mar 12
$120 total
Mar 11 - Mar 12
Total with taxes and fees
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
I bought things like plates, towels,
Reviewed on Mar 8, 2026

The Inn at Patrick Square
115 Market Street Clemson SC
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $176 total per night from Mar 15 to Mar 16
$176 total
Mar 15 - Mar 16
Total with taxes and fees
A 24-hour gym is featured at this hotel, along with free self parking. WiFi in public areas is free. Staff at the 24-hour front desk can provide around-the-clock ...
This was an amazing hotel and we will def be back! We stayed in the suite and highly Recommend! Yes front spot parking!
Reviewed on Mar 8, 2026

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Mar 11 to Mar 12
$135 total
Mar 11 - Mar 12
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
Great stay again
Reviewed on Mar 7, 2026

Inn @ Clemson
1303 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $87 total per night from Mar 11 to Mar 12
$87 total
Mar 11 - Mar 12
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Close to campus
Reviewed on Mar 3, 2026

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $120 total per night from Mar 23 to Mar 24
$120 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Very clean and quiet place. Conveniently located for everything in the area. Staff were super nice. Would definitely return.
Reviewed on Mar 9, 2026

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Mar 15 to Mar 16
$70 total
Mar 15 - Mar 16
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
I was very pleased with my visit at the Days Inn in Anderson, South Carolina. Jennifer, who was the front desk agent that afternoon was very helpful and even let me check in early. The room was extremely clean and quiet and comfortable. I totally give it five stars for being affordable and friendly ...
Reviewed on Mar 9, 2026

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Mar 11 to Mar 12
$106 total
Mar 11 - Mar 12
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

Wooded Cottage - 3 Mi to Clemson University
Clemson SC
Free WiFi in public areas is available at this cottage.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Keowee hotel reviews by fellow wanderers

The Shepherd Hotel Downtown Clemson
5 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Excellent stay, I highly recommend! Accommodations, location, overall vibe, great food and drinks! "
A verified traveler stayed at The Shepherd Hotel Downtown Clemson
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