Book Hotels in Keowee, SC
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Top Keowee hotels

Wooded Cottage - 3 Mi to Clemson University
Clemson
Free WiFi in public areas is available at this cottage. Take advantage of the free self parking.

The Shepherd Hotel Downtown Clemson
110 Sloan St, Clemson, SC
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $199 total per night from Sep 1 to Sep 2
$199 total
Sep 1 - Sep 2
Total includes taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
Luxury hotel - great location
"Fantastic, BEAUTIFUL hotel!!! Staff were amazing!!!"
Reviewed on Aug 7, 2025

Tru by Hilton Seneca Clemson
13050 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from Aug 31 to Sep 1
$121 total
Aug 31 - Sep 1
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Nice sheets
"Very friendly staff, clean room, everything worked well. Good location. The one random thing I noticed were the sheets were nice and soft, that was a nice plus."
Reviewed on Aug 3, 2025

Lakeside Lodge Clemson
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $137 total per night from Aug 18 to Aug 19
$137 total
Aug 18 - Aug 19
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
Beautiful site but disappointing view
"Was excited about this hotel but was disappointed with the view from the room. I paid for a lake view room but what we got was a view of the retaining wall and forest. Couldn’t see the lake at all. The actual view of the lake from the entire property was through the dense trees except for maybe a ..."
Reviewed on Aug 7, 2025

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $122 total per night from Aug 17 to Aug 18
$122 total
Aug 17 - Aug 18
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"The hotel was very quiet, clean and staff was very friendly!"
Reviewed on Jul 30, 2025

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Aug 18 to Aug 19
$112 total
Aug 18 - Aug 19
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Awesome place to stay"
Reviewed on Aug 4, 2025

Inn @ Clemson
1303 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $104 total per night from Aug 21 to Aug 22
$104 total
Aug 21 - Aug 22
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Love love the Clemson Tiger decor every where !!! Very clean and very easy going welcoming staff and check out !!! Definitely will be staying here when I visit my daughter at Clemson !!!"
Reviewed on Aug 3, 2025

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd, Anderson, SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Aug 11 to Aug 12
$65 total
Aug 11 - Aug 12
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"The original room I got was not cleaned properly. The front dest staff Trinity took great care of me and rectified the issue swiftly and satisfactorily! New building is lovely. Room was spacious and clean. Well maintained and will stay here again."
Reviewed on Aug 4, 2025

Horizon Inn & Suites
3025 N Main Street, Anderson, SC
$56 nightly
The price is $62 total per night from Aug 17 to Aug 18
$62 total
Aug 17 - Aug 18
Total includes taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. Staff at the 24-hour front desk can provide around-the-clock ...
"Very nice"
Reviewed on Jul 16, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Keowee hotel reviews by fellow wanderers

The Shepherd Hotel Downtown Clemson
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Fantastic, BEAUTIFUL hotel!!! Staff were amazing!!!"
A verified traveler stayed at The Shepherd Hotel Downtown Clemson
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An Attraction
- Hotels near Clemson University
- Hotels near Lake Keowee
- Hotels near Lake Jocassee
- Hotels near Lake Hartwell
- Hotels near Devils Fork State Park
- Hotels near Memorial Stadium
- Hotels near Anderson University
- Hotels near Lake Hartwell State Park
- Hotels near T. Ed Garrison Arena
- Hotels near J.B. Red Owens Sports Complex
- Hotels near Oconee State Park
- Hotels near Keowee Key Golf Course
- Hotels near Anderson Mall
- Hotels near Southern Wesleyan University
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- Hotels near Walker Golf Course
- Hotels near Villas at Foxwood Hills
- Hotels near Littlejohn Coliseum
- Hotels near Anderson County Museum
- Hotels near Fort Hill
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- Hotels near South Carolina Botanical Gardens
- Hotels near Stumphouse Mountain Tunnel
- Hotels near Tri-County Technical College
- Hotels near Whitewater Lake
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