Book Hotels in Keowee, SC
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Top Keowee hotels

Wooded Cottage - 3 Mi to Clemson University
Clemson
Free WiFi in public areas is available at this cottage. Take advantage of the free self parking.

The Shepherd Hotel Downtown Clemson
110 Sloan St, Clemson, SC
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $210 total per night from Sep 29 to Sep 30
$210 total
Sep 29 - Sep 30
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
"Excellent everything!"
Reviewed on Sep 19, 2025

Tru by Hilton Seneca Clemson
13050 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $122 total per night from Oct 5 to Oct 6
$122 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"What I liked was the customer service Alexa gave me. Had me sign up for Hilton Rewards program too since she mentioned it. No extra blankets in the room. The stay was excellent. Definitely recommend if in the Clemson area."
Reviewed on Sep 3, 2025

Lakeside Lodge Clemson
13500 Clemson Blvd, Seneca, SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Sep 27 to Sep 28
$135 total
Sep 27 - Sep 28
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
"Great place to stay while visiting our Tiger!"
Reviewed on Sep 20, 2025

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $108 total per night from Sep 28 to Sep 29
$108 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Beautiful facility with indoor balconi"
Reviewed on Sep 16, 2025

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Oct 10 to Oct 11
$101 total
Oct 10 - Oct 11
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"Very good value for this hotel considering its location near Clemson's downtown. Comfortable beds."
Reviewed on Sep 15, 2025

Inn @ Clemson
1303 Tiger Blvd, Clemson, SC
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $103 total per night from Oct 2 to Oct 3
$103 total
Oct 2 - Oct 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Good location"
Reviewed on Sep 20, 2025

Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd, Seneca, SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Oct 5 to Oct 6
$93 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Convenient"
Reviewed on Sep 21, 2025

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd, Anderson, SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $66 total per night from Sep 29 to Sep 30
$66 total
Sep 29 - Sep 30
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Friendly faces, cozy rooms—couldn’t ask for more Great vibes here! Would happily stay again."
Reviewed on Sep 20, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Keowee hotel reviews by fellow wanderers

Quality Inn Seneca Clemson Area US-123
5 out of 5
Posted 5 days ago
Travelocity Verified Review
"Convenient "
A verified traveler from Columbia stayed at Quality Inn Seneca Clemson Area US-123
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An Attraction
- Hotels near Clemson University
- Hotels near Lake Keowee
- Hotels near Lake Jocassee
- Hotels near Lake Hartwell
- Hotels near Devils Fork State Park
- Hotels near Memorial Stadium
- Hotels near Anderson University
- Hotels near Lake Hartwell State Park
- Hotels near T. Ed Garrison Arena
- Hotels near J.B. Red Owens Sports Complex
- Hotels near Oconee State Park
- Hotels near Keowee Key Golf Course
- Hotels near Anderson Mall
- Hotels near Southern Wesleyan University
- Hotels near Tugaloo State Park
- Hotels near Walker Golf Course
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- Hotels near Littlejohn Coliseum
- Hotels near Anderson County Museum
- Hotels near Fort Hill
- Hotels near Keowee-Toxaway State Park
- Hotels near South Carolina Botanical Gardens
- Hotels near Stumphouse Mountain Tunnel
- Hotels near Tri-County Technical College
- Hotels near Whitewater Lake
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