Book Hotels in Jefferson, SC

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Jefferson hotels

Springhill Suites by Marriott Cheraw

Springhill Suites by Marriott Cheraw

3 out of 5
201 Front Street Cheraw SC
$110 nightly
The price is $123 total per night from Jan 4 to Jan 5
$123 total
Jan 4 - Jan 5
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like full breakfast and WiFi in public areas. ...
Great stay

Reviewed on Dec 27, 2025

Opens in a new windowSpringhill Suites by Marriott Cheraw
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

2.5 out of 5
203 East Carolina Ave. Hartsville SC
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $137 total per night from Jan 9 to Jan 10
$137 total
Jan 9 - Jan 10
Total with taxes and fees
This hotel features an outdoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A 24-hour ...
Staff was very friendly and accommodating!! Rooms were very clean!

Reviewed on Dec 13, 2025

Opens in a new windowHampton Inn & Suites Hartsville
The Mantissa Hotel

The Mantissa Hotel

3 out of 5
130 East Carolina Ave Hartsville SC
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $181 total per night from Jan 8 to Jan 9
$181 total
Jan 8 - Jan 9
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...
Excellent staff and in the heart of a beautiful downtown.

Reviewed on Dec 5, 2025

Opens in a new windowThe Mantissa Hotel
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

2.5 out of 5
200 S 4th St Hartsville SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Jan 17 to Jan 18
$94 total
Jan 17 - Jan 18
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
This place was very clean and comfortable. Staff was fantastic. It’s very quiet and that’s what I needed.

Reviewed on Dec 27, 2025

Opens in a new windowFairfield Inn by Marriott Hartsville
Baymont by Wyndham Cheraw

Baymont by Wyndham Cheraw

2.5 out of 5
710 Market St Cheraw SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Jan 4 to Jan 5
$95 total
Jan 4 - Jan 5
Total with taxes and fees
A 24-hour gym is featured at this motel, along with free self parking. Guests will appreciate free perks like self-serve breakfast and WiFi in public areas. ...
The area felt safe, the room was cleaned and the stay was amazing here. I will book here again once I come back to South Carolina

Reviewed on Dec 28, 2025

Opens in a new windowBaymont by Wyndham Cheraw
Super 8 by Wyndham Lancaster

Super 8 by Wyndham Lancaster

2 out of 5
1201 Highway 9 Byp W Lancaster SC
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $68 total per night from Jan 24 to Jan 25
$68 total
Jan 24 - Jan 25
Total with taxes and fees
A restaurant and a seasonal outdoor pool are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Clean. Polite, helpful staff. Very thin walls. TV was turned on at 5 am in the neighboring room and I couldn't sleep.

Reviewed on Dec 7, 2025

Opens in a new windowSuper 8 by Wyndham Lancaster
Days Inn by Wyndham Monroe NC

Days Inn by Wyndham Monroe NC

1.5 out of 5
1608 E. Roosevelt Blvd. Monroe NC
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Jan 5 to Jan 6
$75 total
Jan 5 - Jan 6
Total with taxes and fees
A bar/lounge and a 24-hour front desk are featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast ...
Very good place to stay

Reviewed on Aug 8, 2025

Opens in a new windowDays Inn by Wyndham Monroe NC
Red Roof Inn & Suites Monroe, NC

Red Roof Inn & Suites Monroe, NC

2 out of 5
608 West Roosevelt Blvd, STE E Monroe NC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from Jan 8 to Jan 9
$71 total
Jan 8 - Jan 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the business center and onsite ...
Clean room and kind people at check in.

Reviewed on Oct 26, 2025

Opens in a new windowRed Roof Inn & Suites Monroe, NC
Rodeway Inn Monroe

Rodeway Inn Monroe

2 out of 5
611 W Roosevelt Blvd Monroe NC
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $62 total per night from Jan 8 to Jan 9
$62 total
Jan 8 - Jan 9
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
Room is too old. Water is leak. They ate on remodeling.

Reviewed on Dec 19, 2025

Opens in a new windowRodeway Inn Monroe
Don't see what you're looking for?
See all available properties in Jefferson
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Jefferson?
Family getaways are where amazing memories are made, but it's no secret that traveling with little ones can be a challenge. These kid-friendly Jefferson hotels offer perks that aim to keep young and old alike relaxed and happy: Your entourage will enjoy staying at Guest Lodge Pageland. Express check-out services and a picnic area are just a few of the things that help make this place a sought-after option. Also check out the deals at Remodeled historic house, near Pageland, with WI-FI and parking FREE. It comes with extra bedding, clothes washing facilities and lots of opportunities for precious family time.
Where can I find cheap hotels in Jefferson?
At Travelocity you'll find really nice hotels in Jefferson at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Jefferson rather than in Jefferson. We may find you even better rates, too.
How do I find the best Jefferson hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Jefferson then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Jefferson?
The cheapest hotel in Jefferson is $62. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Jefferson?
There are 84 hotels in Jefferson on Travelocity.
What are the best hotels in Jefferson?
Jefferson has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Jefferson for you!
When is the best time to visit Jefferson?
If you want the joy of a fun-filled trip in peak season, visit Jefferson during May, August and September. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Jefferson?
Based on historic data is usually the cheapest month to visit Jefferson. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Jefferson?
There are multiple hotels in Jefferson that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Jefferson. We have plenty of kid-friendly hotels in Jefferson to choose from on Travelocity!
Why book a hotel in Jefferson through Travelocity?
Because we have the top hotels in Jefferson! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Jefferson on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Jefferson hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity