Book Hotels in Jefferson, SC
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Top Jefferson hotels

Springhill Suites by Marriott Cheraw
201 Front Street Cheraw SC
$127 nightly
The price is $142 total per night from Apr 12 to Apr 13
$142 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like full breakfast and WiFi in public areas. ...
The hotel was excellent, clean, well maintained and well worth the cost.
Reviewed on Mar 29, 2026

The Mantissa Hotel
130 East Carolina Ave Hartsville SC
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $101 total per night from Apr 9 to Apr 10
$101 total
Apr 9 - Apr 10
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...
very nice rooms, clean and modern. Ericka, the general manager was a delight. extremely friendly and outgoing!
Reviewed on Mar 30, 2026

Hampton Inn & Suites Hartsville
203 East Carolina Ave. Hartsville SC
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $138 total per night from May 8 to May 9
$138 total
May 8 - May 9
Total with taxes and fees
This hotel features an outdoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A 24-hour ...
Jasmine at the front desk has been wonderful both times I’ve stayed! The rooms are clean, quiet, and comfortable.
Reviewed on Apr 6, 2026

Fairfield Inn by Marriott Hartsville
200 S 4th St Hartsville SC
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from May 8 to May 9
$89 total
May 8 - May 9
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
It was nice
Reviewed on Mar 30, 2026

Quality Inn Cheraw
885 Chesterfield Hwy Cheraw SC
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from May 3 to May 4
$89 total
May 3 - May 4
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
The breakfast wasnt 100% since they was only waffles & bread😒
Reviewed on Apr 4, 2026

Baymont by Wyndham Cheraw
710 Market St Cheraw SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Apr 8 to Apr 9
$95 total
Apr 8 - Apr 9
Total with taxes and fees
A 24-hour gym is featured at this motel, along with free self parking. Guests will appreciate free perks like self-serve breakfast and WiFi in public areas. ...
Room was clean but property was pretty beat up.
Reviewed on Apr 5, 2026

Super 8 by Wyndham Lancaster
1201 Highway 9 Byp W Lancaster SC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Apr 24 to Apr 25
$76 total
Apr 24 - Apr 25
Total with taxes and fees
A restaurant and a seasonal outdoor pool are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Toilet was loose. The property appeared run down on the outside.
Reviewed on Mar 22, 2026

The Landmark Inn
1301 South 4th Street Hartsville SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $99 total per night from Apr 8 to Apr 9
$99 total
Apr 8 - Apr 9
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
The parking was fine, although they could use more lighting in the parking area and at the entrance of the hotel
Reviewed on Mar 31, 2026

Rodeway Inn Monroe
611 W Roosevelt Blvd Monroe NC
Fully refundableReserve now, pay when you stay
$49 nightly
The price is $55 total per night from Apr 13 to Apr 14
$55 total
Apr 13 - Apr 14
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Jefferson hotel reviews by fellow wanderers

Hampton Inn & Suites Hartsville
5 out of 5
Posted 10 hours ago
Travelocity Verified Review
"Jasmine at the front desk has been wonderful both times I’ve stayed! The rooms are clean, quiet, and comfortable. "
A verified traveler stayed at Hampton Inn & Suites Hartsville
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