Book Hotels in Jefferson, SC

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top hotels

Springhill Suites by Marriott Cheraw

Springhill Suites by Marriott Cheraw

3 out of 5
201 Front Street, Cheraw, SC
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like full breakfast and WiFi in public areas. ...
"The staff was very pleasant, rooms were nice"

Reviewed on Jun 15, 2025

Get rates
Springhill Suites by Marriott Cheraw
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

2.5 out of 5
200 S 4th St, Hartsville, SC
Fully refundableReserve now, pay when you stay
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Very quiet and clean. My only complaint is the few options available for breakfest compared to other hotels."

Reviewed on May 29, 2025

Get rates
Fairfield Inn by Marriott Hartsville
Baymont by Wyndham Cheraw

Baymont by Wyndham Cheraw

2.5 out of 5
710 Market St, Cheraw, SC
Fully refundableReserve now, pay when you stay
A 24-hour gym is featured at this motel, along with free self parking. Guests will appreciate free perks like self-serve breakfast and WiFi in public areas. ...
"The room was decent the hotel itself looks run down on the outside and lots of crack heads running around the property and people sleeping in their car on the property I would definitely like to get my money back"

Reviewed on Jun 15, 2025

Get rates
Baymont by Wyndham Cheraw
Super 8 by Wyndham Lancaster

Super 8 by Wyndham Lancaster

2 out of 5
1201 Highway 9 Byp W, Lancaster, SC
Fully refundableReserve now, pay when you stay
A restaurant and a seasonal outdoor pool are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"I was surprised at the cleanliness of the room and bathroom and the staff was very nice"

Reviewed on May 25, 2025

Get rates
Super 8 by Wyndham Lancaster
The Landmark Inn

The Landmark Inn

2.5 out of 5
1301 South 4th Street, Hartsville, SC
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
One nighter
"Room was clean but needed a better comforter."

Reviewed on Apr 21, 2025

Get rates
The Landmark Inn
Red Roof Inn & Suites Monroe, NC

Red Roof Inn & Suites Monroe, NC

2 out of 5
608 West Roosevelt Blvd, STE E, Monroe, NC
Fully refundableReserve now, pay when you stay
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the business center and onsite ...
"Very nice"

Reviewed on Jun 18, 2025

Get rates
Red Roof Inn & Suites Monroe, NC
Quality Inn

Quality Inn

2.5 out of 5
903 S 5th Street, Hartsville, SC
Fully refundableReserve now, pay when you stay
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the laundry ...
"Everything was amazing"

Reviewed on Jun 6, 2025

Get rates
Quality Inn
Super 8 by Wyndham Monroe

Super 8 by Wyndham Monroe

2 out of 5
350 Venus St, Monroe, NC
Fully refundableReserve now, pay when you stay
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
"How the staff was extremely helpful and understanding and everything was clean"

Reviewed on May 29, 2025

Get rates
Super 8 by Wyndham Monroe
Love Highland Cows? Experience them up close in our tiny house in Jefferson, SC

Love Highland Cows? Experience them up close in our tiny house in Jefferson, SC

Jefferson
This vacation home features a garden, laundry facilities, and barbecue grills.
Get rates
Love Highland Cows? Experience them up close in our tiny house in Jefferson, SC
Don't see what you're looking for?
See all available properties in Jefferson
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Jefferson?
Family getaways are where amazing memories are made, but it's no secret that traveling with little ones can be a challenge. These kid-friendly Jefferson hotels offer perks that aim to keep young and old alike relaxed and happy: Your entourage will enjoy staying at Guest Lodge Pageland. Express check-out services and a picnic area are just a few of the things that help make this place a sought-after option. Also check out the deals at Remodeled historic house, near Pageland, with WI-FI and parking FREE. It comes with extra bedding, clothes washing facilities and lots of opportunities for precious family time.
Where can I find cheap hotels in Jefferson?
At Travelocity you'll find really nice hotels in Jefferson at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Jefferson rather than in Jefferson. We may find you even better rates, too.
How do I find the best Jefferson hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Jefferson then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Jefferson?
The cheapest hotel in Jefferson is . This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Jefferson?
There are 76 hotels in Jefferson on Travelocity.
What are the best hotels in Jefferson?
Jefferson has so many great hotels to choose from at Travelocity --- and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Jefferson for you!
When is the best time to visit Jefferson?
If you want the joy of a fun-filled trip in peak season, visit Jefferson during May, August and September. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Jefferson?
Based on historic data is usually the cheapest month to visit Jefferson. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Jefferson?
There are multiple hotels in Jefferson that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Jefferson. We have plenty of kid-friendly hotels in Jefferson to choose from on Travelocity!
Why book a hotel in Jefferson through Travelocity?
Because we have the top hotels in Jefferson! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Jefferson on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Jefferson hotel reviews by fellow wanderers

Red Roof Inn & Suites Monroe, NC

Red Roof Inn & Suites Monroe, NC

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Very nice"
A verified traveler stayed at Red Roof Inn & Suites Monroe, NC
Red Roof Inn & Suites Monroe, NC
Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity