
Exclusive 21c Museum Hotel Vacation Deals

21c Museum Hotel vacation package deals
Price found within the past 48 hours. Click for updated prices.


Louisville Marriott Downtown
Downtown Louisville
Price was $702, price is now $511 per person
$511
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip non-stop flight included
Houston (IAH) to Louisville (SDF)
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a 24-hour gym on site, and laundry facilities and concierge services are also offered.

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
Price was $529, price is now $390 per person
$390
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip non-stop flight included
Houston (IAH) to Louisville (SDF)
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the seasonal outdoor pool, bar/lounge, and snack bar/deli.

Omni Louisville Hotel
Downtown Louisville
Price was $650, price is now $488 per person
$488
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip non-stop flight included
Houston (IAH) to Louisville (SDF)
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Make the most of the 24-hour gym and hot tub, and relax with drinks at one of the 3 bars/lounges.

Hotel Distil, Autograph Collection
Downtown Louisville
Price was $655, price is now $511 per person
$511
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip non-stop flight included
Houston (IAH) to Louisville (SDF)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and valet parking. There's a rooftop terrace on site, and a 24-hour front desk and express check-out are also provided.

The Grady
Downtown Louisville
Price was $728, price is now $577 per person
$577
per person
Feb 26 - Mar 1
found 1 day ago
Roundtrip non-stop flight included
Houston (IAH) to Louisville (SDF)
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.
Frequently asked questions
Top 21c Museum Hotel hotel deals

Galt House Hotel Trademark Collection by Wyndham
140 North Fourth Street Louisville KY
Free Cancellation
Reserve now, pay when you stay
$133 nightly
The price is $157 total per night
$157 total
Dec 15 - Dec 16
Total with taxes and fees
A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. You'll appreciate the seasonal outdoor pool, bar/lounge, and snack bar/deli.
Pool
Spa

Omni Louisville Hotel
400 S. 2nd Street Louisville KY
Free Cancellation
Reserve now, pay when you stay
$167 nightly
The price is $197 total per night
$197 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Make the most of the 24-hour gym and hot tub, and relax with drinks at one of the 3 bars/lounges.
Pool
Hot Tub

Holiday Inn Express & Suites Louisville Downtown by IHG
800 W Market St Louisville KY
Free Cancellation
$93 nightly
The price is $109 total per night
$109 total
Dec 8 - Dec 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Business travelers can take advantage of the 24-hour business center. There's a 24-hour gym on site, and laundry facilities and free newspapers are also offered.
Breakfast included
Free WiFi
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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