Explore top 2026 5 Star Hotels in West Seneca
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Top West Seneca 5 Star hotels
Curtiss Hotel, an Ascend Collection Hotel
"Room and facilities were adequate but below my expectations for “Buffalo’s only 5-star hotel”. Shower was very nice with several fun options for alternate shower heads and strong water pressure. I had an 8am flight out and the valet didn’t open until 7am (no one told me this when I checked in with ..."
Reviewed on Aug 12, 2026
Five Star Hotels in West Seneca
Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in West Seneca to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. West Seneca 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in West Seneca before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent West Seneca hotel reviews by fellow wanderers
La Quinta Inn & Suites by Wyndham Buffalo Amherst
"Conveniently situated right off I-290, making it extremely easy to access the surrounding nearby dining and shopping options. Clean & Comfortable Rooms: The room was clean, quiet, and well-maintained. The beds provide a great night's sleep, and rooms come equipped with helpful amenities like a mini-fridge and microwave. A huge plus for anyone traveling with dogs—the hotel is exceptionally welcoming to pets! Definitely a plus!! A great reliable, clean, and comfortable choice in the Buffalo/Amherst area."
