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Top Santiago 5 Star hotels

NH Collection Plaza Santiago

NH Collection Plaza Santiago

5 out of 5
Avenida Vitacura 2610 Santiago Region Metropolitana
$123 nightly
The price is $123 total per night from Mar 27 to Mar 28
$123 total
Mar 27 - Mar 28
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (1,002 reviews)
Great room. Loved the space and the view. The location was excellent.

Reviewed on Feb 28, 2026

Opens in a new windowNH Collection Plaza Santiago
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$322 nightly
The price is $322 total per night from Mar 28 to Mar 29
$322 total
Mar 28 - Mar 29
This luxury hotel features 2 restaurants, a bar/lounge, and a poolside bar. Families will appreciate the children's pool, kid-friendly dining, and babysitting. ...
9.2/10 Wonderful! (978 reviews)
Room, view, friendly staff and quality facilities made it a great stay.

Reviewed on Feb 26, 2026

Opens in a new windowMandarin Oriental, Santiago
W Santiago

W Santiago

5 out of 5
Isidora Goyenechea 3000 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$279 nightly
The price is $279 total per night from Mar 28 to Mar 29
$279 total
Mar 28 - Mar 29
Ski-in/ski-out access, 3 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, ...
8.8/10 Excellent! (528 reviews)
Great room and friendly and helpful staff.

Reviewed on Feb 25, 2026

Opens in a new windowW Santiago
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

5 out of 5
Calle El Alcalde 15 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$349 nightly
The price is $349 total per night from Mar 28 to Mar 29
$349 total
Mar 28 - Mar 29
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the ski shuttle and onsite ski passes. Traveling on business? Take advantage of the ...
9.4/10 Exceptional! (605 reviews)
Barely acceptable. Definitely does not meet the criteria for a star hotel

Reviewed on Feb 25, 2026

Opens in a new windowThe Ritz-Carlton, Santiago
Noi Vitacura

Noi Vitacura

5 out of 5
Av. Nueva Costanera 3736 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$191 nightly
The price is $191 total per night from Mar 1 to Mar 2
$191 total
Mar 1 - Mar 2
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, free ...
8.6/10 Excellent! (567 reviews)
Clean room, nice rooftop restaurant and very helpful, friendly staff! Thank you, Noi Staff! Ann from SF

Reviewed on Feb 20, 2026

Opens in a new windowNoi Vitacura
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$385 nightly
The price is $385 total per night from Mar 4 to Mar 5
$385 total
Mar 4 - Mar 5
A full-service spa, 2 restaurants, and A 24-hour gym are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like cooked-to-order ...
9.6/10 Exceptional! (701 reviews)
LATAM and Delta changed my seats and not for the better. The hotel was above fabulous and it gets 5 stars.

Reviewed on Feb 25, 2026

Opens in a new windowThe Singular Santiago
Pullman Santiago Vitacura

Pullman Santiago Vitacura

5 out of 5
Av. Vitacura 3201 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $113 total per night from Mar 21 to Mar 22
$113 total
Mar 21 - Mar 22
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...
9/10 Wonderful! (930 reviews)
Coffee and tea in the lobby would have been fantastic! We loved the water!

Reviewed on Feb 22, 2026

Opens in a new windowPullman Santiago Vitacura
LUUM by Norus

LUUM by Norus

5 out of 5
Rep Árabe de Egipto 670 Santiago Santiago
This apartment features a gym and a seasonal outdoor pool. Enjoy the sauna and perks like free self parking. There's in-room fitness on site, and laundry facilities ...
Opens in a new windowLUUM by Norus
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Santiago Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Santiago to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santiago 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Santiago before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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