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Top hotels in Downtown Santiago

Nest Paris-Londres

Nest Paris-Londres

3 out of 5
50 Londres Santiago
$57 nightly
The price is $57 total per night from Feb 17 to Feb 18
$57 total
Feb 17 - Feb 18
A rooftop terrace is featured at this apartment, along with free WiFi in public areas and a communal living room. A picnic area, luggage storage, and concierge ...
Fantastic!! New, with everything you will need for any type of stay. Amazing staff that accommodated every request I needed. You will love it! Thanks guys!

Reviewed on Feb 3, 2026

Opens in a new windowNest Paris-Londres
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$385 nightly
The price is $385 total per night from Feb 10 to Feb 11
$385 total
Feb 10 - Feb 11
A full-service spa, 2 restaurants, and A 24-hour gym are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and free perks like cooked-to-order ...
This was our favorite stay in Chile!

Reviewed on Feb 7, 2026

Opens in a new windowThe Singular Santiago
Hotel Plaza San Francisco

Hotel Plaza San Francisco

4 out of 5
Alameda 816 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $122 total per night from Feb 16 to Feb 17
$122 total
Feb 16 - Feb 17
A full-service spa, a gym, and a restaurant are all featured at this boutique hotel. Traveling on business? Take advantage of the business center, free WiFi ...
The room was very nice. The staff was very helpful and pleasant. The breakfast was lovely. The hotel was located in a great location.

Reviewed on Feb 7, 2026

Opens in a new windowHotel Plaza San Francisco
Lastarria Hotel & Aparts

Lastarria Hotel & Aparts

3 out of 5
José Victorino Lastarria, 43 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $63 total per night from Feb 27 to Feb 28
$63 total
Feb 27 - Feb 28
This aparthotel features free WiFi in public areas, laundry facilities, and self parking. A terrace and a safe deposit box are also provided.
We really enjoyed our stay at Lastarria Apartments. The location if great, very close to the metro. The apartment was clean and we loved the terrace, we really enjoyed the street performers and music every night. The staff is very helpful and nice. There is a laundry service that we were able to ...

Reviewed on Feb 3, 2026

Opens in a new windowLastarria Hotel & Aparts
Luciano K Hotel

Luciano K Hotel

4.5 out of 5
Merced, 84 Santiago Región Metropolitana
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $131 total per night from Mar 5 to Mar 6
$131 total
Mar 5 - Mar 6
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the laundry service ...
We had an amazing stay! The location was perfect, walking distance for anything we wanted to do. The room was great and the staff were very helpful. We dropped our key down a drain on the first day and they easily got us a new one even late at night. Highly recommend laying on the patio and taking ...

Reviewed on Jan 28, 2026

Opens in a new windowLuciano K Hotel
LOFT Hotel by Sommelier Hoteles

LOFT Hotel by Sommelier Hoteles

3 out of 5
264 Miraflores Santiago Santiago
Fully refundableReserve now, pay when you stay
Free WiFi in public areas and luggage storage are available at this hotel. Enjoy the free continental breakfast each morning. Staff at the 24-hour front desk ...
Super artsy, spacious room with breakfast delivered to your room - hotel located in a super safe part in the heart of Santiago.

Reviewed on Jan 11, 2026

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Opens in a new windowLOFT Hotel by Sommelier Hoteles
RQ Santiago

RQ Santiago

3 out of 5
Alameda 1449 Local 11 - Centro Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
This hotel features a coffee shop, concierge services, and self parking. Guests will appreciate free perks like buffet breakfast and WiFi in public areas. Luggage ...
One of the greatest locations in the city ! Close to historical district and plenty of shopping banks and exchanges with in a gated court yard in the heart of the financial district Friendly people Speak poco English .. lol ( English is spoken a littke !

Reviewed on Jan 6, 2026

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Opens in a new windowRQ Santiago
Park Plaza Apart Hotel

Park Plaza Apart Hotel

3 out of 5
Av. Huerfanos 545 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
A gym, free self parking, and laundry facilities are featured at this aparthotel. WiFi in public areas is free. There's luggage storage and multilingual staff ...
Great room great staff great service great price

Reviewed on Jan 26, 2026

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Opens in a new windowPark Plaza Apart Hotel
Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $71 total per night from Feb 22 to Feb 23
$71 total
Feb 22 - Feb 23
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi ...
Good place to stay right downtown. But, like any large city you need to be careful. Lots of shopping and historical sites all within walking distance. Property is a little tired but very clean with super interesting decor. Overall a good spot for a 30 hour layover!

Reviewed on Jan 21, 2026

Opens in a new windowAlmacruz Hotel y Centro de Convenciones
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Downtown Santiago Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Downtown Santiago area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Downtown Santiago to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Downtown Santiago are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Downtown Santiago hotel reviews by fellow wanderers

Hotel Plaza San Francisco

Hotel Plaza San Francisco

5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The room was very nice. The staff was very helpful and pleasant. The breakfast was lovely. The hotel was located in a great location."
A verified traveler stayed at Hotel Plaza San Francisco
Hotel Plaza San Francisco

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