Explore top 2025 5 Star Hotels in Medellin

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Top Medellin 5 Star hotels

The Click Clack Hotel Medellin

Calle 10B # 37-29, Medellín, Antioquia

Fully refundableReserve now, pay when you stay

$180 nightly

$180 total

Oct 7 - Oct 8

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and airport shuttle. ...

NH Collection Medellín Royal

Carrera 42 No 5 Sur 130, El Poblado, Medellín, Antioquia

Fully refundableReserve now, pay when you stay

$91 nightly

$91 total

Oct 3 - Oct 4

A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

Medellin Marriott Hotel

Calle 1a Sur #43a-83, Medellín

Fully refundableReserve now, pay when you stay

$329 nightly

$329 total

Sep 28 - Sep 29

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

Luxury Suites Prana By Cadissa

Calle 35 # 63B-36, Medellín, Antioquia

Fully refundableReserve now, pay when you stay

$161 nightly

$161 total

Sep 12 - Sep 13

This aparthotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the laundry service and ...

30 Living Suites

82C-40 Cl. 30, Medellín, Antioquia

This apartment doesn't skimp on freebies - guests receive free full breakfast and free WiFi. Traveling on business? Take advantage of the business center, conference ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Medellin Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Medellin to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Medellin 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Medellin before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.