Explore top 2025 4 Star Hotels in Santa Cruz

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Top Santa Cruz 4 Star hotels

TRYP by Wyndham Santa Cruz

Av. San Martin, Calle 9 Este, no. 4, Equipetrol., Santa Cruz

$109 nightly

$109 total

Oct 26 - Oct 27

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and free perks like buffet breakfast and free self parking. There's a sauna ...

9.2/10 Wonderful! (140 reviews)

I suggest more fruits for breakfast , very limited options , king staff

Reviewed on Aug 2, 2025

Camino Real Hotel

Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz

$154 nightly

$154 total

Oct 31 - Nov 1

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. There's fun for all ages with a children's pool and a waterslide, ...

8.8/10 Excellent! (401 reviews)

Very comfortable, great location. My favorite in Santa Cruz. Big enough / small enough

Reviewed on Aug 25, 2025

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

San Martin Avenue Esq Street E - E, Santa Cruz

$74 nightly

$74 total

Nov 13 - Nov 14

This hotel features a restaurant, a gym, and a bar/lounge. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...

9.2/10 Wonderful! (250 reviews)

Great customer service!

Reviewed on Oct 2, 2025

Swissôtel Santa Cruz De La Sierra

5to anillo Avenida La Salle # 4500, Santa Cruz

$128 nightly

$128 total

Nov 9 - Nov 10

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...

9.2/10 Wonderful! (79 reviews)

Great night at the Swissotel

It was a great one-night stay at the Santa Cruz Swissôtel. The hotel was impecable, service excellent, and the staff very friendly and professional. We shall return to this hotel in the future.

Reviewed on Jul 14, 2025

Buganvillas Hotel Suites & Spa

Av. Roca y Coronado No. 901, Santa Cruz

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool and barbecue grills. Enjoy the gym and perks ...

7.4/10 Good! (93 reviews)

Extremely satisfy with the service that this resort provided to us. Definitely will return back. Follow me on YouTube #TeamWithERVING

Reviewed on Aug 14, 2021

Get rates

Hotel Maywa

2do anillo av.santacruz #1007, Santa Cruz, Santa Cruz Department

This hotel features a 24-hour gym and a rooftop terrace. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and airport ...

9.2/10 Wonderful! (11 reviews)

The structure and service was fantastic

Reviewed on Sep 17, 2025

Get rates

Royal Lodge Hotel

Avenida San Martin 200, Equipetrol Norte, Santa Cruz

This hotel features an outdoor pool, a gym, and a restaurant. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self ...

Disappointing stay

I was really looking forward to a bit of luxury after travelling for 6 weeks. Unfortunately I was greeted with judgment for having a backpack and then found that the facilities in my room were shocking. There wasn't even any hot water.

Reviewed on Aug 11, 2018

Get rates

Don't see what you're looking for?

See all available properties in Santa Cruz

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Santa Cruz

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Santa Cruz 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Santa Cruz will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Santa Cruz, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.