Explore top 2026 4 Star Hotels in Mediterranean Region

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Top Mediterranean Region 4 Star hotels

Barcelona Airport Hotel

Barcelona Airport Hotel

4 out of 5
Plaza de la Volateria, 3 El Prat de Llobregat
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $160 total per night from Nov 20 to Nov 21
$160 total
Nov 20 - Nov 21
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowBarcelona Airport Hotel
Hotel101- Madrid

Hotel101- Madrid

4 out of 5
Av. de las Fuerzas Armadas, 328 Madrid
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $75 total per night from Nov 22 to Nov 23
$75 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a poolside bar. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Opens in a new windowHotel101- Madrid
Hôtel Saint Georges

Hôtel Saint Georges

4 out of 5
7, Avenue Georges Clemenceau Nice Alpes-Maritimes
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $71 total per night from Nov 16 to Nov 17
$71 total
Nov 16 - Nov 17
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. A coffee shop, a terrace, and a garden are also on offer.
Opens in a new windowHôtel Saint Georges
Hotel Regina

Hotel Regina

4 out of 5
Alcala 19 Madrid Madrid
Fully refundableReserve now, pay when you stay
$226 nightly
The price is $248 total per night from Nov 18 to Nov 19
$248 total
Nov 18 - Nov 19
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
9.8/10 Exceptional! (2,457 reviews)
"Great hotel. Very clean. Very convenient. Easy walk to multiple subway stations and walking distance to most of the Madrid sights. Comfortable bed and the rooms are pretty spacious - especially by European standards. Would definitely stay here again."

Reviewed on Nov 15, 2026

Opens in a new windowHotel Regina
Hotel Emperador

Hotel Emperador

4 out of 5
Gran Via 53 Madrid Madrid
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $166 total per night from Dec 16 to Dec 17
$166 total
Dec 16 - Dec 17
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9.2/10 Wonderful! (2,305 reviews)
"The location is an A+ - walkable to all! We originally were put in a room w a foul odor but after 24 hours they changed our room and things were better."

Reviewed on Nov 14, 2026

Opens in a new windowHotel Emperador
Best Western Hotel Rome Airport

Best Western Hotel Rome Airport

4 out of 5
Via Portuense, 2465 Fiumicino RM
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $176 total per night from Nov 16 to Nov 17
$176 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Opens in a new windowBest Western Hotel Rome Airport
Hotel Riu Plaza España

Hotel Riu Plaza España

4 out of 5
C/ Gran Via, 84 Madrid
$199 nightly
The price is $219 total per night from Nov 30 to Dec 1
$219 total
Nov 30 - Dec 1
Total with taxes and fees
The hotel's gym, seasonal outdoor pool, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center and ...
9.4/10 Exceptional! (5,324 reviews)
"Everything was great! Great staff - Great rooms - The breakfast buffet was unbelievable... it was amazing! We loved it! Totally worth it and Ana (buffet entrance) she was very, very nice! Our room was cleaned every day by Antonia and she was great too!!! She found one of our rings that she found ..."

Reviewed on Nov 15, 2026

Opens in a new windowHotel Riu Plaza España
Hotel Liabeny

Hotel Liabeny

4 out of 5
Calle de la Salud 3 Madrid
$181 nightly
The price is $199 total per night from Nov 29 to Nov 30
$199 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features a restaurant, a sauna, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
9.4/10 Exceptional! (1,643 reviews)
"Great location. Helpful staff, good breakfast. It’s a good choice for a central location in Madrid."

Reviewed on Nov 14, 2026

Opens in a new windowHotel Liabeny
Hard Rock Hotel Madrid

Hard Rock Hotel Madrid

4.5 out of 5
Ronda de Atocha 17 Madrid
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $200 total per night from Dec 16 to Dec 17
$200 total
Dec 16 - Dec 17
Total with taxes and fees
This hotel features 3 bars/lounges, a poolside bar, and a restaurant. Enjoy the 24-hour gym and perks like free WiFi. Enjoy the seasonal outdoor pool and conveniences ...
9.4/10 Exceptional! (3,058 reviews)
"We enjoyed our stay and was close to the city center."

Reviewed on Nov 15, 2026

Opens in a new windowHard Rock Hotel Madrid
Urban Hive Madrid

Urban Hive Madrid

4.5 out of 5
Cuesta de Santo Domingo 9 Madrid
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $202 total per night from Nov 29 to Nov 30
$202 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free WiFi. There's a rooftop terrace on site, ...
9.8/10 Exceptional! (524 reviews)
"The hotel is in a great location. The staff were extremely friendly and helpful. Ride share knew the hotel location and picked us up/ dropped us off right in front of the hotel lobby. The only issue we had was the hot water went out for the hotel late one of the nights. The issue was resolved by ..."

Reviewed on Nov 15, 2026

Opens in a new windowUrban Hive Madrid
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4 Star Hotels Mediterranean Region

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mediterranean Region 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mediterranean Region will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mediterranean Region, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Mediterranean Region hotel reviews by fellow wanderers