Explore top 2026 4 Star Hotels in Mediterranean Region

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Top Mediterranean Region 4 Star hotels

Barcelona Airport Hotel

Barcelona Airport Hotel

4 out of 5
Plaza de la Volateria, 3 El Prat de Llobregat
Fully refundableReserve now, pay when you stay
$188 nightly
The price is $212 total per night from Jun 9 to Jun 10
$212 total
Jun 9 - Jun 10
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (5,092 reviews)
The rooms are way too dark especially if you have an early flight out and no sun. The lighting in the room is awful. There is a hot pot to make tea but no coffee. Can only get coffee at paid breakfast. Shuttle is convenient but you have to load bags on and off van. The driver only drives. They need ...

Reviewed on May 12, 2026

Opens in a new windowBarcelona Airport Hotel
Royal Ramblas

Royal Ramblas

4 out of 5
La Rambla, 117 Barcelona
Fully refundableReserve now, pay when you stay
$220 nightly
The price is $263 total per night from May 31 to Jun 1
$263 total
May 31 - Jun 1
Total with taxes and fees
A restaurant, self parking, and a 24-hour front desk are among this hotel's amenities. WiFi in public areas is free. Express check-out, dry cleaning, and luggage ...
9/10 Wonderful! (1,029 reviews)
Very bad customer service from front desk staff

Reviewed on May 14, 2026

Opens in a new windowRoyal Ramblas
Hilton Rome Airport

Hilton Rome Airport

4 out of 5
Via Arturo Ferrarin 2 Fiumicino RM
Fully refundableReserve now, pay when you stay
$272 nightly
The price is $310 total per night from May 28 to May 29
$310 total
May 28 - May 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
8.2/10 Very Good! (3,250 reviews)
Great overnight option for the early flight out of Rome, walk to airport, Perfect

Reviewed on May 14, 2026

Opens in a new windowHilton Rome Airport
Hilton Garden Inn Rome Airport

Hilton Garden Inn Rome Airport

4 out of 5
Via Vittorio Bragadin 2 Fiumicino RM
$199 nightly
The price is $231 total per night from Jun 8 to Jun 9
$231 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
8.2/10 Very Good! (3,795 reviews)
Convenient shuttle. Fast and efficient service in dining room.

Reviewed on May 14, 2026

Opens in a new windowHilton Garden Inn Rome Airport
Titania Hotel

Titania Hotel

4 out of 5
52 Panepistimiou Avenue Athens Attiki
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $164 total per night from May 17 to May 18
$164 total
May 17 - May 18
Total with taxes and fees
This smoke-free hotel's 2 restaurants, 2 bars/lounges, and gym are some of the featured amenities. Families will appreciate the onsite laundry facilities, kid-friendly ...
8/10 Very Good! (947 reviews)
Great breakfast. Clean rooms. Helpful staff.

Reviewed on May 10, 2026

Opens in a new windowTitania Hotel
Senator Barajas Hotel

Senator Barajas Hotel

4 out of 5
Galeon 27 Madrid Madrid
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $111 total per night from May 17 to May 18
$111 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
8.4/10 Very Good! (1,698 reviews)
Was not able to make it. So I cannot make a review

Reviewed on May 11, 2026

Opens in a new windowSenator Barajas Hotel
Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$276 nightly
The price is $321 total per night from May 17 to May 18
$321 total
May 17 - May 18
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, free WiFi in public areas, and laundry ...
8.6/10 Excellent! (1,925 reviews)
The property is historic and we loved the ambience that is provided. The hotel is very central to transportation, shopping, and lovely restaurants. Would definitely stay again.

Reviewed on May 11, 2026

Opens in a new windowHotel Quirinale
SANA Metropolitan Hotel

SANA Metropolitan Hotel

4 out of 5
Rua Soeiro Pereira Gomes, Parcela 2 Lisbon
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $156 total per night from Jun 8 to Jun 9
$156 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities, kid-friendly dining, and in-room childcare. ...
8.8/10 Excellent! (537 reviews)
Outstandingly lovely staff., perfectly located. Couldn’t have asked for more.

Reviewed on May 3, 2026

Opens in a new windowSANA Metropolitan Hotel
The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini

4 out of 5
Viale Spartaco Lavagnini 70 72 Florence FI
Fully refundableReserve now, pay when you stay
$182 nightly
The price is $217 total per night from Jun 2 to Jun 3
$217 total
Jun 2 - Jun 3
Total with taxes and fees
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9/10 Wonderful! (1,357 reviews)
Breakfast was amazing. Room was clean and bed was comfy

Reviewed on May 12, 2026

Opens in a new windowThe Social Hub Florence Lavagnini
Novotel Madrid Center

Novotel Madrid Center

4 out of 5
O'donnell 53 Madrid Madrid
Fully refundableReserve now, pay when you stay
$207 nightly
The price is $227 total per night from Jun 12 to Jun 13
$227 total
Jun 12 - Jun 13
Total with taxes and fees
This hotel features 2 bars/lounges, a poolside bar, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
9.2/10 Wonderful! (1,190 reviews)
We stayed overnight for a connecting flight to Mallorca next day. Lovely hotel and staff!

Reviewed on May 12, 2026

Opens in a new windowNovotel Madrid Center
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4 Star Hotels Mediterranean Region

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mediterranean Region 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mediterranean Region will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mediterranean Region, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Mediterranean Region hotel reviews by fellow wanderers