Explore top 2026 4 Star Hotels in Grafton

Name: Historic Main Street Heritage Retreat
Rating: 9.4

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Top Grafton 4 Star hotels

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO

Fully refundableReserve now, pay when you stay

$118 nightly

$138 total

Dec 19 - Dec 20

Total with taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

8.4/10 Very Good! (1,049 reviews)

Great hotel. Will definitely stay again.

Reviewed on Nov 25, 2025

Ameristar Casino Resort and Spa

1 Ameristar Blvd St. Charles MO

Fully refundableReserve now, pay when you stay

$166 nightly

$194 total

Dec 14 - Dec 15

Total with taxes and fees

This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...

8.4/10 Very Good! (1,000 reviews)

Clean. Effortless check-in. Great time!

Reviewed on Dec 2, 2025

Marriott St. Louis Airport

10700 Pear Tree Lane St. Louis MO

Fully refundableReserve now, pay when you stay

$128 nightly

$152 total

Dec 19 - Dec 20

Total with taxes and fees

This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center, express check-in, and free airport ...

7.8/10 Good! (1,002 reviews)

Room was good, however the heating would not shut off and it was extremely hot. Maintenance came up and tried to fix and gave us a box fan.

Reviewed on Dec 6, 2025

DoubleTree by Hilton St. Louis - Westport

1973 Craigshire Rd Maryland Heights MO

Fully refundableReserve now, pay when you stay

$110 nightly

$127 total

Dec 28 - Dec 29

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8/10 Very Good! (1,000 reviews)

Fantastic Place To Stay!

Reviewed on Nov 26, 2025

DoubleTree by Hilton St. Louis Airport

4505 Woodson Road St. Louis MO

Fully refundableReserve now, pay when you stay

$102 nightly

$119 total

Jan 4 - Jan 5, 2026

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Bring the family and enjoy the arcade/game room and kid-friendly dining. There's no skimping ...

7.8/10 Good! (857 reviews)

Very friendly, helpful staff. Clean organized hotel.

Reviewed on Nov 30, 2025

Historic Main Street Heritage Retreat

Saint Charles MO

This apartment features laundry facilities.

9.4/10 Exceptional! (37 reviews)

Great location!

Reviewed on Nov 10, 2025

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Beall Mansion An Elegant Bed & Breakfast Inn

407 E. 12th St. Alton IL

This bed & breakfast features free WiFi in public areas, concierge services, and free self parking. Enjoy the 4 hot tubs and free continental breakfast each ...

Excellent bed and breakfast!

Wonderful stay! This home is beautiful. Our hosts Sandy and Jim were gracious and it was a pleasure to be with them for the evening. Highly recommended!

Reviewed on Oct 21, 2024

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Grafton

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Grafton 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Grafton will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Grafton, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.