Book Hotels in Stem, NC
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Top Stem hotels

JB Duke Hotel
230 Science Drive Durham NC
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $226 total per night from Mar 15 to Mar 16
$226 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A business center, ...
Exceeded our expectations
Reviewed on Mar 3, 2026

The Durham Hotel
315 East Chapel Hill Street Durham NC
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $211 total per night from Mar 15 to Mar 16
$211 total
Mar 15 - Mar 16
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center ...
Staff were delightful, room quiet, great location
Reviewed on Mar 1, 2026

University Inn Durham next to Duke University Medical Center
502 Elf St Durham NC
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $129 total per night from Mar 13 to Mar 14
$129 total
Mar 13 - Mar 14
Total with taxes and fees
This hotel includes free WiFi in public areas and laundry facilities. A free area shuttle is offered as well. Self parking is offered and the front desk is staffed ...
No breakfast orovuded, room was just okay. Staff wasn't very friemdly yoy pay to park.
Reviewed on Mar 8, 2026

Hilton Durham near Duke University
3800 Hillsborough Rd Durham NC
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $129 total per night from Mar 15 to Mar 16
$129 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling for business? Take advantage of the free WiFi in public areas, express check-out, ...
My stay was great. Thx to all
Reviewed on Mar 8, 2026

Comfort Inn & Suites Durham near Duke University
1816 Hillandale Rd Durham NC
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $119 total per night from Mar 22 to Mar 23
$119 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Was here to have surgery. The room was smaller than photoed I got the room with the sofa bed in case we needed spare bed, to not bother my hubby. The water pressure on 5th floor was weak at best. But the staff was so friendly and helpful. I reported my few issues to the checkout clerk and otherwise ...
Reviewed on Mar 9, 2026

21c Museum Hotel Durham
111 North Corcoran Street Durham NC
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $187 total per night from Apr 5 to Apr 6
$187 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the sauna and perks like free WiFi. Valet parking, a 24-hour business center, and dry ...
Staff was very kind and accommodating.
Reviewed on Mar 5, 2026

Courtyard Durham Near Duke University/Downtown
1815 Front St Durham NC
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $134 total per night from Mar 12 to Mar 13
$134 total
Mar 12 - Mar 13
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
A couple of good places to eat nearby --- walkable. It was an easy place to stay while traveling north on 1-85.
Reviewed on Mar 7, 2026

Unscripted Durham, Part of JDV by Hyatt
202 N Corcoran St Durham NC
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $142 total per night from Apr 7 to Apr 8
$142 total
Apr 7 - Apr 8
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Doors had holes at the bottom that allowed the light to come in and probably critters (I didn’t see any). The outdoor deck was nice and sunny.
Reviewed on Mar 3, 2026

Millennium Durham
2800 Campus Walk Ave Durham NC
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $113 total per night from Mar 11 to Mar 12
$113 total
Mar 11 - Mar 12
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Clean place, bad cell service inside.
Reviewed on Mar 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Stem hotel reviews by fellow wanderers

Comfort Inn & Suites Durham near Duke University
4 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Was here to have surgery. The room was smaller than photoed I got the room with the sofa bed in case we needed spare bed, to not bother my hubby.
The water pressure on 5th floor was weak at best. But the staff was so friendly and helpful. I reported my few issues to the checkout clerk and otherwise would and likely will stay here again. "
A verified traveler stayed at Comfort Inn & Suites Durham near Duke University
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