Book Hotels in Stem, NC
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Top Stem hotels

JB Duke Hotel
230 Science Drive Durham NC
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $226 total per night from Feb 24 to Feb 25
$226 total
Feb 24 - Feb 25
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Guests will appreciate free perks like free self parking and WiFi in public areas. A business center, ...
Everything was good
Reviewed on Feb 18, 2026

AC Hotel Durham
2800 Erwin Road Durham NC
$152 nightly
The price is $173 total per night from Mar 13 to Mar 14
$173 total
Mar 13 - Mar 14
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, and express ...
This hotel is very well located for those who need to be near Duke University Hospital. The room was very comfortable and clean. There are several restaurants nearby. Breakfast is not included, but it's available for a reasonable price. I definitely recommend it. The staff was very friendly.
Reviewed on Feb 6, 2026

The Durham Hotel
315 East Chapel Hill Street Durham NC
Fully refundableReserve now, pay when you stay
$186 nightly
The price is $211 total per night from Mar 1 to Mar 2
$211 total
Mar 1 - Mar 2
Total with taxes and fees
The hotel's 24-hour gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center ...
The room was very nice, staff was very helpful, and it's a great location.
Reviewed on Feb 10, 2026

Comfort Inn & Suites Durham near Duke University
1816 Hillandale Rd Durham NC
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $121 total per night from Mar 1 to Mar 2
$121 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Clean room, great staff, quiet
Reviewed on Feb 20, 2026

Hilton Durham near Duke University
3800 Hillsborough Rd Durham NC
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $129 total per night from Mar 1 to Mar 2
$129 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling for business? Take advantage of the free WiFi in public areas, express check-out, ...
Wasn’t bad but could have been cleaner
Reviewed on Feb 19, 2026

21c Museum Hotel Durham
111 North Corcoran Street Durham NC
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $187 total per night from Mar 15 to Mar 16
$187 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the sauna and perks like free WiFi. Valet parking, a 24-hour business center, and dry ...
Noting really stood out about the hotel; however, the bellmen were great!!!!!
Reviewed on Feb 19, 2026

Courtyard Durham Near Duke University/Downtown
1815 Front St Durham NC
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $129 total per night from Feb 25 to Feb 26
$129 total
Feb 25 - Feb 26
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Always a clean environment, rooms fitness center ect. Staff very nice
Reviewed on Feb 20, 2026

Unscripted Durham, Part of JDV by Hyatt
202 N Corcoran St Durham NC
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $151 total per night from Mar 22 to Mar 23
$151 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Loved how centrally located this hotel is, loved acted to the parking garage without having to take an elevator, loved it in general. Thanks!
Reviewed on Feb 19, 2026

Millennium Durham
2800 Campus Walk Ave Durham NC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $112 total per night from Feb 25 to Feb 26
$112 total
Feb 25 - Feb 26
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Room was great, nice to sleep in a king bed. Loved the location, right by Duke University.
Reviewed on Feb 8, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Stem hotel reviews by fellow wanderers

Comfort Inn & Suites Durham near Duke University
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Clean room, great staff, quiet"
A verified traveler stayed at Comfort Inn & Suites Durham near Duke University
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