Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels

Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Jul 12 to Jul 13
$125 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Clean rooms, fabulous happy hour and amenities."
Reviewed on Jun 17, 2026

Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from Jul 5 to Jul 6
$123 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"I loved everything about the property except the part of not changing the sheets. They made the bed but not changed the sheets???"
Reviewed on Jun 15, 2026

The Principal Hotel
310 S Main St Columbia IL
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $125 total per night from Jun 25 to Jun 26
$125 total
Jun 25 - Jun 26
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Free self parking, a coffee shop, and dry cleaning are also offered.
"i have stayed here twice before and i loved it, but i will not be returning! i went through cancer and i get cold easily, they now have a lock box on the thermostat and it is set at 69 degrees! you cannot shut the air off and the front desk person can't either! so they are wasting money making the ..."
Reviewed on Jun 17, 2026

Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $125 total per night from Jun 28 to Jun 29
$125 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"The manager and all the staff were so helpful The food was good. We did use the pool and jacuzzi and everything was clean Definitely will recommend"
Reviewed on Jun 14, 2026

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $110 total per night from Jun 21 to Jun 22
$110 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Signed up for 2 Queen need room, when arrived it was not available so had to get king bed which was super uncomfortable and also took forever for staff to figure out what was going on."
Reviewed on Jun 15, 2026

Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundable
$113 nightly
The price is $127 total per night from Jun 21 to Jun 22
$127 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"The hotel was easy to locate and parking was plentiful."
Reviewed on Jun 16, 2026

Quality Inn O'Fallon IL - St. Louis
1409 W US 50 O'Fallon IL
Fully refundable
$76 nightly
The price is $87 total per night from Jun 21 to Jun 22
$87 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"This was terrible no working elevator and a multitude of ants in our room"
Reviewed on Jun 13, 2026

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $62 total per night from Jun 18 to Jun 19
$62 total
Jun 18 - Jun 19
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"The lady at the front desk was rude and trying to watch a tv show while assisting me so it took forever because she wasn’t focused on her job. They did not advise me there is no elevator so I walked around the entire building looking for one with all of my bags.. extremely inconvenient. The halls ..."
Reviewed on Jun 17, 2026

Welcome Suites
148 Regency Park O'Fallon IL
Fully refundableReserve now, pay when you stay
$46 nightly
The price is $53 total per night from Jun 18 to Jun 19
$53 total
Jun 18 - Jun 19
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A picnic area and barbecue grills are also ...
"1. I always do the book now and pay later so I know what I’m paying for when I get to the hotel 2. I called the hotel to make sure me arriving early the next morning was ok and they said yes and for some reason they checked me in and charged my card. 3. I wasn’t made aware of that til I went to cancel ..."
Reviewed on Jun 8, 2026
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels

Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$56 nightly
The price is $63 total per night from Jun 21 to Jun 22
$63 total
Jun 21 - Jun 22
Total with taxes and fees
6.4/10 (1,008 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating

4 Star Hotels
3 properties
Recent Southwest Illinois hotel reviews by fellow wanderers

The Principal Hotel
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Everything was clean and there was plenty of parking. The attached restaurant had delicious food."
A verified traveler stayed at The Principal Hotel
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