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Top Southwest Illinois hotels

Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from May 10 to May 11
$123 total
May 10 - May 11
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Very friendly spacious and clean! Great people
Reviewed on Apr 16, 2026

Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $115 total per night from Apr 26 to Apr 27
$115 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
The room was quiet and had comfortable beds. The free snacks (5:30 - 7:00) were delicious and enough for a meal. Breakfast was also excellent :)
Reviewed on Apr 16, 2026

Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $78 total per night from May 10 to May 11
$78 total
May 10 - May 11
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Yes everything was wonderful
Reviewed on Apr 14, 2026

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $120 total per night from May 6 to May 7
$120 total
May 6 - May 7
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Clean room! Super friendly staff! Easy access and parking!
Reviewed on Apr 17, 2026

Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundable
$113 nightly
The price is $127 total per night from Apr 20 to Apr 21
$127 total
Apr 20 - Apr 21
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
The breakfast menu was typical. It wasn’t bad. The bats were great. The room was OK. Bathrooms were updated, but the carpet was in need of being pulled out. I had a lot of warning areas in the carpet in my room, especially since they accept dogs there I didn’t wanna walk on it.
Reviewed on Apr 17, 2026

Super 8 by Wyndham Troy IL/St. Louis Area
910 Edwardsville Rd Troy IL
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $80 total per night from Apr 26 to Apr 27
$80 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
The hotel was ready to access, rooms were adequate and breakfast was good.
Reviewed on Apr 16, 2026

Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr East St. Louis IL
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from May 5 to May 6
$79 total
May 5 - May 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
The pool was closed, gym treadmill was broken, room smelled, toilet chain was off
Reviewed on Apr 7, 2026

Quality Inn O'Fallon IL - St. Louis
1409 W US 50 O'Fallon IL
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $68 total per night from Apr 19 to Apr 20
$68 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Plenty of shops near by, rooms mostly clean, bathrooms very small, shower head older model, plenty of security cameras.
Reviewed on Apr 13, 2026

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$51 nightly
The price is $59 total per night from Apr 26 to Apr 27
$59 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
I had to yell for someone to come to the desk. The room was not clean and the sheets had stains. No bugs. The extra lock on the door as loose.
Reviewed on Apr 14, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels

Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$60 nightly
The price is $68 total per night from Apr 20 to Apr 21
$68 total
Apr 20 - Apr 21
Total with taxes and fees
6.4/10 (1,004 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating

4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers

Drury Inn & Suites St. Louis Fairview Heights
5 out of 5
Posted 9 hours ago
Travelocity Verified Review
"Clean room! Super friendly staff! Easy access and parking!"
A verified traveler stayed at Drury Inn & Suites St. Louis Fairview Heights
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