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Top Southwest Illinois hotels

The Principal Hotel
310 S Main St Columbia IL
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $117 total per night from Jun 4 to Jun 5
$117 total
Jun 4 - Jun 5
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Free self parking, a coffee shop, and dry cleaning are also offered.
"This is a beautiful property! The staff was very helpful and friendly. Very clean and comfortable."
Reviewed on May 29, 2026

Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Jun 7 to Jun 8
$125 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"This is the best hotel chain. If there is one in the area stay here!! The food and drinks are always fantastic. So clean, comfy, and quiet."
Reviewed on Jun 2, 2026

Walker's Bluff Casino Resort
777 Walkers Bluff Way Carterville IL
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $147 total per night from Jun 3 to Jun 4
$147 total
Jun 3 - Jun 4
Total with taxes and fees
This luxury resort features a casino, a full-service spa, and 3 restaurants. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
"Nice hotel!"
Reviewed on Jun 1, 2026

Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $121 total per night from Jun 14 to Jun 15
$121 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"We came in after hiking. The hotel was clean. There was a happy hour with heavy enough apps that it was our dinner in the evening and a hot breakfast in the morning. Every staff person we met was proactively friendly and helpful. Would definitely return to any Drury hotel."
Reviewed on Jun 1, 2026

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Jun 14 to Jun 15
$114 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Very nice stay my wife and I had. Enjoyed the free food in the evening and breakfast. Very clean all around. Staff was very friendly."
Reviewed on May 31, 2026

Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr East St. Louis IL
Fully refundable
$83 nightly
The price is $93 total per night from Jun 8 to Jun 9
$93 total
Jun 8 - Jun 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"The rooms we’re half cleaned the beds we’re dirty i noticed after turning the sheets Down to go to sleep there was dirt and debris the pool water was salty don’t ask and breakfast was cold no tongs to pick up food it wasn’t flavorful the batter for waffles was sour tasting no milk that I seen I did ..."
Reviewed on May 24, 2026

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $68 total per night from Jun 15 to Jun 16
$68 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Terrible do not stay here"
Reviewed on Jun 2, 2026

Welcome Suites
148 Regency Park O'Fallon IL
Fully refundableReserve now, pay when you stay
$46 nightly
The price is $53 total per night from Jun 3 to Jun 4
$53 total
Jun 3 - Jun 4
Total with taxes and fees
A gym, free self parking, and laundry facilities are featured at this hotel. WiFi in public areas is free. A picnic area and barbecue grills are also ...
"Cockroaches!!!!! Yes thats what I said. There were cockroaches. My family and I was getting ready for bed and my daughter found a cockroach. After looking around there were multiple roaches. EWE!!! GROSS!!! We immediately packed our things and got out of there. Its been 2 weeks and still no ..."
Reviewed on May 30, 2026

Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $133 total per night from Jun 7 to Jun 8
$133 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels

Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$59 nightly
The price is $67 total per night from Jun 3 to Jun 4
$67 total
Jun 3 - Jun 4
Total with taxes and fees
6.4/10 (1,002 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating

4 Star Hotels
3 properties
Recent Southwest Illinois hotel reviews by fellow wanderers

Holiday Inn Express & Suites Mount Vernon by IHG
2 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Staff was super friendly and nice, but the room was disgusting and dated. It had an odor and a couple bugs plus a dirty bathroom and tables."
A verified traveler stayed at Holiday Inn Express & Suites Mount Vernon by IHG
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