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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Jan 14 to Jan 15
$125 total
Jan 14 - Jan 15
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Enjoyed my stay. Always good.
Reviewed on Jan 9, 2026
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from Jan 18 to Jan 19
$123 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Everything was great. Only note I would add is an extra blanket in the room would have been nice.
Reviewed on Jan 6, 2026
Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $78 total per night from Jan 22 to Jan 23
$78 total
Jan 22 - Jan 23
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Everything was excellent?
Reviewed on Dec 30, 2025
Holiday Inn Express Troy by IHG
2011 Formosa Road Troy IL
Fully refundable
$107 nightly
The price is $119 total per night from Jan 25 to Jan 26
$119 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Clean, updated, nice staff
Reviewed on Jan 7, 2026
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Jan 15 to Jan 16
$106 total
Jan 15 - Jan 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Clean room and friendly staff
Reviewed on Jan 6, 2026
Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $123 total per night from Jan 11 to Jan 12
$123 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Courteous staff, clean room
Reviewed on Jan 8, 2026
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr Collinsville IL
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $96 total per night from Feb 1 to Feb 2
$96 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
staff courtious
Reviewed on Jan 5, 2026
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$43 nightly
The price is $50 total per night from Jan 18 to Jan 19
$50 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
All good
Reviewed on Jan 3, 2026
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
136 Regency Park O'Fallon IL
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $67 total per night from Jan 11 to Jan 12
$67 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Staff was Amazing upon check-in. So grateful they allowed cash deposit, especially after my card was stolen. I stopped by another hotel I've stayed at previously and was not willing to work with me. They were very adamant about having a card on file for deposit 🙄. I would most definitely stay at ...
Reviewed on Jan 4, 2026
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$60 nightly
The price is $68 total per night from Jan 12 to Jan 13
$68 total
Jan 12 - Jan 13
Total with taxes and fees
6.2/10 (1,004 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
4 properties
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