Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels

Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Nov 23 to Nov 24
$106 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Nice place…
Reviewed on Nov 10, 2025

The Principal Hotel
310 S Main St Columbia IL
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $117 total per night from Dec 11 to Dec 12
$117 total
Dec 11 - Dec 12
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Free self parking, a coffee shop, and dry cleaning are also offered.
Everything was great.
Reviewed on Nov 15, 2025

Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive, O'Fallon, IL
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $118 total per night from Nov 23 to Nov 24
$118 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Great place
Reviewed on Nov 14, 2025

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Nov 20 to Nov 21
$106 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Room was clean. Staff was great
Reviewed on Nov 9, 2025

Best Western Plus Pontoon Beach
4 Regency Pkwy, Granite City, IL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Nov 19 to Nov 20
$95 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Everything was nice
Reviewed on Nov 10, 2025

Red Lion Inn & Suites Pontoon Beach
1240 E Chain Of Rocks Rd, Granite City, IL
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Nov 19 to Nov 20
$70 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
Clean room
Reviewed on Nov 13, 2025

Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr, East St. Louis, IL
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $76 total per night from Nov 23 to Nov 24
$76 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Staff very cordial. We were satisfied with our stay. Location is near food and commerce options. LOTS of handicap parking = the WHOLE front row near the building. Trim strip missing in bathroom made it appear less than clean. HARD TO GET IN & OUT OF TUB FOR BATH as only one puny grab bar = likely ...
Reviewed on Nov 4, 2025

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
$48 nightly
The price is $56 total per night from Nov 23 to Nov 24
$56 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The room was very comfortable with a good layout. The mattress was comfortable. The climate control was easy to operate and efficient. Every staff member we met was friendly.
Reviewed on Nov 9, 2025

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr, Collinsville, IL
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Nov 23 to Nov 24
$92 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
I paid the pet fee , there was no dog bags or empty waste basket for dog waste . Staff was friendly
Reviewed on Nov 13, 2025
Don't see what you're looking for?
See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels

Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr, Caseyville, IL
$62 nightly
The price is $70 total per night from Nov 17 to Nov 18
$70 total
Nov 17 - Nov 18
Total with taxes and fees
6.2/10 (1,002 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating

4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
The Principal Hotel
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Everything was great."
A verified traveler stayed at The Principal Hotel
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