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Top Southwest Illinois hotels

Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from Mar 15 to Mar 16
$123 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
One of the elevators was out of order for over 24 hours. Made it slow going.
Reviewed on Mar 4, 2026

Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Apr 3 to Apr 4
$125 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Definitely
Reviewed on Mar 3, 2026

Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $122 total per night from Apr 5 to Apr 6
$122 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Excellent kickstart and breakfast!
Reviewed on Mar 3, 2026

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
$94 nightly
The price is $106 total per night from Apr 1 to Apr 2
$106 total
Apr 1 - Apr 2
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Staff was extremely friendly, check in process was smooth. Our room was clean and comfortable.
Reviewed on Mar 5, 2026

Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $122 total per night from Apr 5 to Apr 6
$122 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
I was not impressed with the front staff on the day I checked in. She was trying to help me, but she was also talking on the phone. My opinion it didn't sound like a business call. :(
Reviewed on Mar 6, 2026

Quality Inn O'Fallon IL - St. Louis
1409 W US 50 O'Fallon IL
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $64 total per night from Mar 8 to Mar 9
$64 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
The room was fairly clean. The remote didn’t work. Probably needed batteries. The bathtub surround needs to be replaced. It was quiet and the beds were very comfortable.
Reviewed on Mar 6, 2026

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $65 total per night from Mar 15 to Mar 16
$65 total
Mar 15 - Mar 16
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Hotel hallways smelled like Woodstock revisited. The carpet in the hallways and rooms were beyond worn out. What they called gravy had consistency of lumpy mashed potatoes. I could’ve stayed in alley and it would’ve been cleaner than this place
Reviewed on Mar 5, 2026

Comfort Suites Fairview Heights - St. Louis
137 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $90 total per night from Apr 1 to Apr 2
$90 total
Apr 1 - Apr 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
My check in was amazing with a young lady, but my issue was with a guy, the over night staff, trying give me a plunger for a toilet problem. The issue was taken care of and thank U to the young lady
Reviewed on Mar 3, 2026

Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive Fairview Heights IL
Fully refundable
$86 nightly
The price is $97 total per night from Apr 6 to Apr 7
$97 total
Apr 6 - Apr 7
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Pool was basically down. The heater was broken. You could swim at your own risk…but waaay too cold to actually swim. No drain stopper in the tub, so had to use a hand towel. Looks a lot better online than in person. Not a terrible experience, but not the best either. 3/5 overall for sure.
Reviewed on Mar 6, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels

Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$63 nightly
The price is $71 total per night from Mar 8 to Mar 9
$71 total
Mar 8 - Mar 9
Total with taxes and fees
6.4/10 (1,000 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating

4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers

Quality Inn O'Fallon IL - St. Louis
4 out of 5
Posted 8 hours ago
Travelocity Verified Review
"The room was fairly clean. The remote didn’t work. Probably needed batteries. The bathtub surround needs to be replaced. It was quiet and the beds were very comfortable."
A verified traveler stayed at Quality Inn O'Fallon IL - St. Louis
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