Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Jan 18 to Jan 19
$125 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Enjoyed my stay. Always good.
Reviewed on Jan 9, 2026
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from Jan 25 to Jan 26
$123 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Everything here was great, the staff, the room, the pool, and all of the complimentary items like breakfast, dinner, and drinks. Will definitely be staying here again.
Reviewed on Jan 12, 2026
Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $78 total per night from Feb 1 to Feb 2
$78 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Clean room, and quiet. Nice location with restaurants close by.
Reviewed on Jan 8, 2026
Holiday Inn Express Troy by IHG
2011 Formosa Road Troy IL
Fully refundable
$102 nightly
The price is $113 total per night from Feb 1 to Feb 2
$113 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Clean, updated, nice staff
Reviewed on Jan 7, 2026
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Jan 19 to Jan 20
$106 total
Jan 19 - Jan 20
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Clean room and friendly staff
Reviewed on Jan 6, 2026
Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $123 total per night from Jan 16 to Jan 17
$123 total
Jan 16 - Jan 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Yes very clean
Reviewed on Jan 11, 2026
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr Collinsville IL
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $90 total per night from Feb 1 to Feb 2
$90 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The room seemed claen. The bed was great, everything was great. Except for the shower, when they did a remodel they made the shower door slide the wrong way. There is zero chance of turning the water on without getting blast of cold sprayed on you! So that made me think, i see the cleaners in the ...
Reviewed on Jan 12, 2026
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$43 nightly
The price is $49 total per night from Jan 25 to Jan 26
$49 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The staff was very friendly and the room looked fantastic
Reviewed on Jan 6, 2026
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
136 Regency Park O'Fallon IL
$59 nightly
The price is $67 total per night from Jan 18 to Jan 19
$67 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Staff was Amazing upon check-in. So grateful they allowed cash deposit, especially after my card was stolen. I stopped by another hotel I've stayed at previously and was not willing to work with me. They were very adamant about having a card on file for deposit 🙄. I would most definitely stay at ...
Reviewed on Jan 4, 2026
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$60 nightly
The price is $68 total per night from Jan 16 to Jan 17
$68 total
Jan 16 - Jan 17
Total with taxes and fees
6.2/10 (1,004 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Drury Inn & Suites St. Louis O'Fallon, IL
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Everything here was great, the staff, the room, the pool, and all of the complimentary items like breakfast, dinner, and drinks. Will definitely be staying here again."
A verified traveler stayed at Drury Inn & Suites St. Louis O'Fallon, IL
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