Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels

Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
$90 nightly
The price is $102 total per night from Nov 22 to Nov 23
$102 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"I give the room a 8 out of ten"
Reviewed on Nov 12, 2026

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr Collinsville IL
$86 nightly
The price is $99 total per night from Nov 22 to Nov 23
$99 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"For the money you pay, this is a good buy! The staaff is friendly and helpful. I would stay,again!"
Reviewed on Nov 13, 2026

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
$51 nightly
The price is $59 total per night from Nov 21 to Nov 22
$59 total
Nov 21 - Nov 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Upon entry into a completely dark room, I tried to find a light switch and when I did the bulb was burned out. Fine. Found another light. There were too many things plugged into the outlet with the microwave, fridge, TV and lamps. The TV went off when I used the microwave. I got it all to work finally. ..."
Reviewed on Nov 12, 2026

Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
$111 nightly
The price is $125 total per night from Nov 22 to Nov 23
$125 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...

Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
$102 nightly
The price is $118 total per night from Nov 22 to Nov 23
$118 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...

Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$59 nightly
The price is $67 total per night from Nov 16 to Nov 17
$67 total
Nov 16 - Nov 17
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. A snack bar/deli is provided and ...

The Principal Hotel
310 S Main St Columbia IL
$92 nightly
The price is $102 total per night from Nov 16 to Nov 17
$102 total
Nov 16 - Nov 17
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Free self parking, a coffee shop, and dry cleaning are also offered.

Comfort Inn Edwardsville - St. Louis
3080 S State Route 157 Edwardsville IL
$87 nightly
The price is $100 total per night from Nov 29 to Nov 30
$100 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...

Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
$94 nightly
The price is $113 total per night from Nov 29 to Nov 30
$113 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels

Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$59 nightly
The price is $67 total per night from Nov 16 to Nov 17
$67 total
Nov 16 - Nov 17
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating

4 Star Hotels
3 properties
Recent Southwest Illinois hotel reviews by fellow wanderers

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
4 out of 5
Posted 17 hours ago
Travelocity Verified Review
"For the money you pay, this is a good buy! The staaff is friendly and helpful. I would stay,again!"
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
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