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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Dec 4 to Dec 5
$106 total
Dec 4 - Dec 5
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Room was clean. Plenty of towels etc. Quite, no noise in the hallway the entire night.
Reviewed on Nov 28, 2025
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $118 total per night from Dec 7 to Dec 8
$118 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Great front desk service
Reviewed on Nov 25, 2025
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Dec 4 to Dec 5
$106 total
Dec 4 - Dec 5
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Every clean everyone was so nice and polite will definitely stay again
Reviewed on Nov 23, 2025
Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $123 total per night from Dec 1 to Dec 2
$123 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Friendly staff. Great room. Nice place to stay!
Reviewed on Nov 26, 2025
Best Western Plus Pontoon Beach
4 Regency Pkwy Granite City IL
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Dec 7 to Dec 8
$95 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
The STAFF! We loved the staff and all of our interactions with them! They’re the most friendly humans :) the coffee machine in the lobby is also super fancy and I had the BEST hotel coffee I’ve ever had (and that’s a huge compliment because I’m super picky with my coffee). We felt super safe and ...
Reviewed on Nov 21, 2025
Super 8 by Wyndham Troy IL/St. Louis Area
910 Edwardsville Rd Troy IL
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Dec 1 to Dec 2
$71 total
Dec 1 - Dec 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Yes was clean rooms
Reviewed on Nov 9, 2025
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr East St. Louis IL
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $77 total per night from Dec 7 to Dec 8
$77 total
Dec 7 - Dec 8
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Great place to stop for the night on a trip. The bed was comfortable. I didn't use the Internet much, but it seemed to work. Breakfast had cereal, eggs & sausage, waffles, yogurt, toast, and juice. Not a fancy place, but very good for my needs.
Reviewed on Nov 20, 2025
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$43 nightly
The price is $50 total per night from Dec 8 to Dec 9
$50 total
Dec 8 - Dec 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Breakfast was horrible. Staff not very friendly. But my room was clean and wasnt bothered by anyone so it all evens out in the end
Reviewed on Nov 19, 2025
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr Collinsville IL
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $85 total per night from Dec 21 to Dec 22
$85 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Clean room, friendly staff and the breakfast was pretty good
Reviewed on Nov 20, 2025
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$58 nightly
The price is $65 total per night from Dec 7 to Dec 8
$65 total
Dec 7 - Dec 8
Total with taxes and fees
6.2/10 (1,004 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Drury Plaza Hotel Mt. Vernon
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Room was clean. Plenty of towels etc. Quite, no noise in the hallway the entire night."
A verified traveler stayed at Drury Plaza Hotel Mt. Vernon
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