Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Oct 26 to Oct 27
$106 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Clean room. Very nice staff. Always enjoy the meals"
Reviewed on Oct 16, 2025
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $106 total per night from Oct 21 to Oct 22
$106 total
Oct 21 - Oct 22
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"Friendly and helpful staff"
Reviewed on Oct 9, 2025
Comfort Suites Mount Vernon
404 South 44th Street, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $123 total per night from Oct 19 to Oct 20
$123 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Breakfast was adequate, room was nice, spacious, bed comfortable, staff were friendly and helpful, only complaint was the pool was cold and the hot tub jets didn't work properly"
Reviewed on Oct 15, 2025
Best Western Plus Pontoon Beach
4 Regency Pkwy, Granite City, IL
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $100 total per night from Oct 19 to Oct 20
$100 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Very quiet and clean"
Reviewed on Oct 16, 2025
Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive, Fairview Heights, IL
Fully refundable
$76 nightly
The price is $85 total per night from Oct 26 to Oct 27
$85 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Yes"
Reviewed on Oct 9, 2025
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr, East St. Louis, IL
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $80 total per night from Nov 4 to Nov 5
$80 total
Nov 4 - Nov 5
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Great hotel for the price"
Reviewed on Sep 21, 2025
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
$49 nightly
The price is $57 total per night from Nov 16 to Nov 17
$57 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"We enjoyed our stay.... Ty"
Reviewed on Oct 9, 2025
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr, Collinsville, IL
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $95 total per night from Nov 2 to Nov 3
$95 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Did not use gym; pool closed for fall."
Reviewed on Oct 9, 2025
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
136 Regency Park, O'Fallon, IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $75 total per night from Oct 19 to Oct 20
$75 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Fast friendly check-in! Clean room!"
Reviewed on Oct 10, 2025
Don't see what you're looking for?
See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr, Caseyville, IL
$62 nightly
The price is $70 total per night from Oct 19 to Oct 20
$70 total
Oct 19 - Oct 20
Total with taxes and fees
6.2/10 (1,004 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Drury Plaza Hotel Mt. Vernon
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Clean room. Very nice staff. Always enjoy the meals "
A verified traveler stayed at Drury Plaza Hotel Mt. Vernon
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