Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $125 total per night from Oct 25 to Oct 26
$125 total
Oct 25 - Oct 26
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
"Best hotel i've ever been in"
Reviewed on Oct 15, 2026
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $118 total per night from Oct 19 to Oct 20
$118 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"3 day stay, room was never cleaned! They the do not disturb sign was on the door, I told them not true. It’s has been laying on the desk the whole time we stayed there. I ask for a reduction in rate because I did get what I paid for. They told me they could not reduce the rate because I made my reservation ..."
Reviewed on Oct 15, 2026
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Nov 1 to Nov 2
$102 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
"I've stayed at this particular Drury a couple of times now and am most impressed with the staff. My only complaint was that we were to late for the nightly drinks and treats that you have for the guests..."
Reviewed on Oct 13, 2026
Best Western St. Louis Fairview Heights
150 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $90 total per night from Nov 9 to Nov 10
$90 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Thank you"
Reviewed on Oct 15, 2026
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
Fully refundable
$59 nightly
The price is $67 total per night from Oct 17 to Oct 18
$67 total
Oct 17 - Oct 18
Total with taxes and fees
A seasonal outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. A snack bar/deli is provided and ...
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
$53 nightly
The price is $61 total per night from Nov 1 to Nov 2
$61 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The Principal Hotel
310 S Main St Columbia IL
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $99 total per night from Oct 19 to Oct 20
$99 total
Oct 19 - Oct 20
Total with taxes and fees
A restaurant and a gym are featured at this hotel. Free self parking, a coffee shop, and dry cleaning are also offered.
Comfort Inn Edwardsville - St. Louis
3080 S State Route 157 Edwardsville IL
Fully refundable
$89 nightly
The price is $103 total per night from Oct 21 to Oct 22
$103 total
Oct 21 - Oct 22
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr East St. Louis IL
Fully refundable
$75 nightly
The price is $85 total per night from Nov 11 to Nov 12
$85 total
Nov 11 - Nov 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$59 nightly
The price is $67 total per night from Oct 17 to Oct 18
$67 total
Oct 17 - Oct 18
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
3 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Best Western St. Louis Fairview Heights
5 out of 5
Posted 10 hours ago
Travelocity Verified Review
"Thank you"
A verified traveler stayed at Best Western St. Louis Fairview Heights
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