Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Jan 4 to Jan 5
$106 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Nice and clean place. Friendly staff.
Reviewed on Dec 21, 2025
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from Jan 4 to Jan 5
$123 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Arrived early on Christmas Day. Promptly greeted by the front desk. Checked in quickly and made it to our room. Very clean and nice suite. Everything worked and the staff was very friendly.
Reviewed on Dec 27, 2025
Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $78 total per night from Jan 5 to Jan 6
$78 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Clean room and nice staff.
Reviewed on Dec 21, 2025
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from Jan 4 to Jan 5
$106 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
The drinks and dinner kick back was great nice hotel.
Reviewed on Dec 26, 2025
Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $123 total per night from Dec 30 to Dec 31
$123 total
Dec 30 - Dec 31
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Staff was amazing, from receptionist to housekeeping. Clean. Even had Elf on the Shelf hidden for kids to find and get a prize.
Reviewed on Dec 26, 2025
Country Inn & Suites by Radisson, Fairview Heights, IL
140 Ludwig Drive Fairview Heights IL
Fully refundable
$87 nightly
The price is $99 total per night from Dec 31 to Jan 1
$99 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Clean and newly renovated rooms. Breakfast was standard- cereal, muffins, and waffles.
Reviewed on Dec 21, 2025
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr Collinsville IL
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $94 total per night from Jan 11 to Jan 12
$94 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Staff
Reviewed on Dec 22, 2025
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$44 nightly
The price is $51 total per night from Jan 4 to Jan 5
$51 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Clean, lots of space, comfortable
Reviewed on Dec 23, 2025
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
136 Regency Park O'Fallon IL
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $63 total per night from Dec 29 to Dec 30
$63 total
Dec 29 - Dec 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
The hotel and surrounding area was quiet with great restaurants and shopping nearby.
Reviewed on Dec 27, 2025
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$58 nightly
The price is $65 total per night from Jan 1 to Jan 2
$65 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
6.2/10 (1,001 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Drury Inn & Suites St. Louis O'Fallon, IL
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Arrived early on Christmas Day. Promptly greeted by the front desk. Checked in quickly and made it to our room. Very clean and nice suite. Everything worked and the staff was very friendly. "
A verified traveler stayed at Drury Inn & Suites St. Louis O'Fallon, IL
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