Book Hotels in Southwest Illinois, IL
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Top Southwest Illinois hotels
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $124 total per night from Feb 12 to Feb 13
$124 total
Feb 12 - Feb 13
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
One of the nicest places. Great food, night and day
Reviewed on Feb 2, 2026
Drury Inn & Suites St. Louis O'Fallon, IL
1118 Central Park Drive O'Fallon IL
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $123 total per night from Feb 8 to Feb 9
$123 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Beautiful property, well managed.
Reviewed on Jan 31, 2026
Drury Inn & Suites Marion
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $78 total per night from Feb 23 to Feb 24
$78 total
Feb 23 - Feb 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Our room was clean and tidy.
Reviewed on Feb 2, 2026
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Feb 11 to Feb 12
$102 total
Feb 11 - Feb 12
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Clean room, comfortable bed, easy check in, friendly staff.
Reviewed on Feb 1, 2026
Comfort Suites Mount Vernon
404 South 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $123 total per night from Feb 6 to Feb 7
$123 total
Feb 6 - Feb 7
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Size and condition of room
Reviewed on Feb 1, 2026
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
3396 Green Mount Crossing Drive Shiloh O'Fallon IL
Fully refundable
$114 nightly
The price is $127 total per night from Feb 17 to Feb 18
$127 total
Feb 17 - Feb 18
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
always very consistent....young lady at check in was great and also the gentleman at check just as good....will use this property again... dc
Reviewed on Feb 1, 2026
Quality Inn O'Fallon IL - St. Louis
1409 W US 50 O'Fallon IL
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $61 total per night from Feb 15 to Feb 16
$61 total
Feb 15 - Feb 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Great love it
Reviewed on Feb 2, 2026
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr Collinsville IL
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Feb 22 to Feb 23
$87 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The room seemed claen. The bed was great, everything was great. Except for the shower, when they did a remodel they made the shower door slide the wrong way. There is zero chance of turning the water on without getting blast of cold sprayed on you! So that made me think, i see the cleaners in the ...
Reviewed on Jan 12, 2026
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $57 total per night from Feb 8 to Feb 9
$57 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Room and service amazing as always
Reviewed on Feb 3, 2026
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See all available properties in Southwest Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southwest Illinois hotels
Motel 6 Caseyville, IL - Caseyville Il
2431 Old Country Inn Dr Caseyville IL
$60 nightly
The price is $68 total per night from Feb 8 to Feb 9
$68 total
Feb 8 - Feb 9
Total with taxes and fees
6.2/10 (1,000 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southwest Illinois with star-rating
Check Southwest Illinois Hotels by Star Rating
4 Star Hotels
4 properties
Recent Southwest Illinois hotel reviews by fellow wanderers
Super 8 by Wyndham O'Fallon
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Room and service amazing as always"
A verified traveler stayed at Super 8 by Wyndham O'Fallon
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