Find and compare business hotels in Southern Illinois, IL from $63

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top Southern Illinois Convention Center Hotels

Holiday Inn Express & Suites Effingham by IHG

Holiday Inn Express & Suites Effingham by IHG

2.5 out of 5
1604 West Fayette Avenue, Effingham, IL
Free Cancellation
$103 nightly
The price is $116 total per night
$116 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St, Marion, IL
Free Cancellation
Reserve now, pay when you stay
$65 nightly
The price is $78 total per night
$78 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57

2.5 out of 5
2403 Black Diamond Dr, Marion, IL
Free Cancellation
Reserve now, pay when you stay
$108 nightly
The price is $130 total per night
$130 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Harrah's Metropolis Hotel & Casino

Harrah's Metropolis Hotel & Casino

3.5 out of 5
100 E Front St, Metropolis, IL
$113 nightly
The price is $125 total per night
$125 total
Nov 11 - Nov 12
Total with taxes and fees
This hotel features a casino and 2 restaurants. Relax with a drink at the bar/lounge and enjoy perks like free self parking and free WiFi. A snack bar/deli, ...
Red Roof Inn St Louis - Troy, IL

Red Roof Inn St Louis - Troy, IL

2 out of 5
2030 Formosa Road, Troy, IL
Free Cancellation
Reserve now, pay when you stay
$68 nightly
The price is $75 total per night
$75 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Radisson Hotel Fairview Heights - St. Louis

Radisson Hotel Fairview Heights - St. Louis

3 out of 5
319 Fountains Pkwy, Fairview Heights, IL
Free Cancellation
$80 nightly
The price is $90 total per night
$90 total
Oct 15 - Oct 16
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Super 8 by Wyndham Mattoon

Super 8 by Wyndham Mattoon

2 out of 5
205 Mcfall Rd, Mattoon, IL
Free Cancellation
Reserve now, pay when you stay
$67 nightly
The price is $75 total per night
$75 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Econo Lodge Inn & Suites Fairview Heights - St. Louis

Econo Lodge Inn & Suites Fairview Heights - St. Louis

2 out of 5
305 Salem Pl, Fairview Heights, IL
Free Cancellation
Reserve now, pay when you stay
$64 nightly
The price is $72 total per night
$72 total
Nov 11 - Nov 12
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Super 8 by Wyndham Belleville St. Louis Area

Super 8 by Wyndham Belleville St. Louis Area

2 out of 5
600 East Main Street, Hwy 159 and E Main St, Belleville, IL
Free Cancellation
Reserve now, pay when you stay
$61 nightly
The price is $70 total per night
$70 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. A computer station ...
Days Inn by Wyndham Collinsville/St. Louis

Days Inn by Wyndham Collinsville/St. Louis

2.5 out of 5
12 Commerce Drive, I-55/70 and IL 157, Collinsville, IL
Free Cancellation
Reserve now, pay when you stay
$59 nightly
The price is $67 total per night
$67 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Multilingual staff at the 24-hour front desk ...
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

3 out of 5
6 Gateway Dr, Collinsville, IL
Free Cancellation
Reserve now, pay when you stay
$82 nightly
The price is $95 total per night
$95 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Super 8 by Wyndham Collinsville St. Louis

Super 8 by Wyndham Collinsville St. Louis

2 out of 5
2 Gateway Dr, Collinsville, IL
Free Cancellation
Reserve now, pay when you stay
$55 nightly
The price is $63 total per night
$63 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Don't see what you're looking for?
See all available properties in Southern Illinois
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Conference Hotels in Southern Illinois

Is your boss sending you off to Southern Illinois for an important business meeting? Or maybe you're in town to attend a big conference? Travelocity's wide range of Southern Illinois conference hotels are here to fulfill all of your business travel needs.

Whether you're planning a large, company-wide meeting or a small board meeting, the Southern Illinois business hotels have you covered. These properties cater to business travelers with in-room Wi-Fi, work desks, and meeting rooms of varying sizes. Grab a drink at the lobby bar to mingle with co-workers you only see once a year or buy a drink for a potential new client. You can also use the on property fitness center to blow off some steam before your big presentation. You're guaranteed to impress your boss when you book a stay at one of Travelocity's Southern Illinois conference hotels.

Relax in the comfortable rooms and crush your work presentation knowing you got the best deal on your business hotel in Southern Illinois. Book your accommodations today and experience the value and customer service of Travelocity.

Southern Illinois hotels essential information

Accommodation
1,083 hotels
Lowest Price
$63
Highest Price
$130
Popular hotels
Drury Inn & Suites Marion, Radisson Hotel Fairview Heights - St. Louis, Harrah's Metropolis Hotel & Casino, Super 8 by Wyndham Mattoon, Super 8 by Wyndham Collinsville St. Louis, Red Roof Inn St Louis - Troy, IL, Econo Lodge Inn & Suites Fairview Heights - St. Louis, Super 8 by Wyndham Belleville St. Louis Area, Comfort Inn & Suites Marion I-57, Days Inn by Wyndham Collinsville/St. Louis, Holiday Inn Express & Suites Effingham by IHG, La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Recent Southern Illinois hotel reviews by fellow wanderers

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Everything sparkled. "
A verified traveler stayed at Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon

Explore More Ways to Travel with Travelocity