Hotels with Restaurants in Southeast Missouri from $62
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Southeast Missouri Hotels with Restaurants

Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Cape Girardeau MO
This apartment featured laundry facilities and barbecue grills.

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $85 total per night
$85 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
$100 nightly
The price is $113 total per night
$113 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd Poplar Bluff MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $102 total per night
$102 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...

Hampton Inn Poplar Bluff
2420 Crestwood Dr Poplar Bluff MO
Free Cancellation
Reserve now, pay when you stay
$91 nightly
The price is $102 total per night
$102 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business ...

Drury Inn & Suites Hayti Caruthersville
1317 E Highway 84 Hayti MO
Free Cancellation
Reserve now, pay when you stay
$98 nightly
The price is $112 total per night
$112 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
$72 nightly
The price is $81 total per night
$81 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$74 nightly
The price is $85 total per night
$85 total
Dec 3 - Dec 4
Total with taxes and fees
This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour ...

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $108 total per night
$108 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...

Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
$98 nightly
The price is $110 total per night
$110 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
Free Cancellation
Reserve now, pay when you stay
$54 nightly
The price is $62 total per night
$62 total
Nov 10 - Nov 11
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

Holiday Inn Poplar Bluff by IHG
2781 N Westwood Blvd Poplar Bluff MO
Free Cancellation
$79 nightly
The price is $89 total per night
$89 total
Dec 5 - Dec 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Missouri hotels essential information
Accommodation | 698 hotels |
|---|---|
Lowest Price | $62 |
Highest Price | $113 |
Popular hotels | Drury Inn & Suites Hayti Caruthersville, Drury Inn & Suites Jackson MO, Drury Inn & Suites Sikeston, MO, Hampton Inn Cape Girardeau I 55 East, Drury Inn & Suites Poplar Bluff, Baymont Inn and Suites by Wyndham Farmington, MO, Holiday Inn Poplar Bluff by IHG, Best Western Plus Sikeston I-55, Pear Tree Inn Cape Girardeau West, Drury Plaza Hotel Cape Girardeau Conference Center, Hampton Inn Poplar Bluff, Historical 'Kage House' Short Term Rental located in "Old Town Cape" |
Recent Southeast Missouri hotel reviews by fellow wanderers

Hampton Inn Poplar Bluff
5 out of 5
Posted 9 hours ago
Travelocity Verified Review
"Met ll expectations for a clean and comfortable room. Breakfast was excellent, with cheese omelets, bacon, biscuits, and gravy. Staff was excellent."
A verified traveler stayed at Hampton Inn Poplar Bluff
More ways to wander Southeast Missouri
Flights to Southeast Missouri
The best fares to get you there
Southeast Missouri Hotels
Southeast Missouri Vacation Rentals
Great Deals on Alternative Accommodations
Southeast Missouri Car Rentals
Affordable cars to get you around town
Southeast Missouri Vacations
Save more by combining flights, hotels and cars
Things to do in Southeast Missouri


