Explore 12 Luxury Hotels in South Indianapolis

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Best Luxury Hotels in South Indianapolis

Comfort Inn Indianapolis South I-65

Comfort Inn Indianapolis South I-65

3514 S Keystone Avenue Indianapolis IN
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $91 total per night from Dec 2 to Dec 3
$91 total
Dec 2 - Dec 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
7.8/10 Good! (1,001 reviews)
"My family stays here whenever we are in the area. The rooms were clean. Because we were at a night when there was a school group that stayed at the same time, the hallways were a bit noisy to no fault of the hotel management. It quieted down after somebody told them to keep it down. I don’t know ..."

Reviewed on Nov 2, 2026

Opens in a new windowComfort Inn Indianapolis South I-65
Red Roof Inn Indianapolis South

Red Roof Inn Indianapolis South

5221 Victory Dr Indianapolis IN
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $65 total per night from Nov 8 to Nov 9
$65 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Staff at the 24-hour front desk can provide around-the-clock ...
7.4/10 Good! (776 reviews)
"Clean space with the essential elements. Staff were very helpful and friendly."

Reviewed on Nov 2, 2026

Opens in a new windowRed Roof Inn Indianapolis South
Country Inn & Suites by Radisson, Indianapolis South, IN

Country Inn & Suites by Radisson, Indianapolis South, IN

4325 Southport Crossings Way Indianapolis IN
Fully refundable
$84 nightly
The price is $98 total per night from Nov 29 to Nov 30
$98 total
Nov 29 - Nov 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
Opens in a new windowCountry Inn & Suites by Radisson, Indianapolis South, IN
Baymont by Wyndham Indianapolis South

Baymont by Wyndham Indianapolis South

4402 E Creek View Rd Indianapolis IN
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $80 total per night from Nov 11 to Nov 12
$80 total
Nov 11 - Nov 12
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Opens in a new windowBaymont by Wyndham Indianapolis South
La Quinta Inn & Suites by Wyndham Indianapolis South

La Quinta Inn & Suites by Wyndham Indianapolis South

5120 Victory Drive Indianapolis IN
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $100 total per night from Nov 8 to Nov 9
$100 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Relax with ...
Opens in a new windowLa Quinta Inn & Suites by Wyndham Indianapolis South
Super 8 by Wyndham Indianapolis/Southport Rd

Super 8 by Wyndham Indianapolis/Southport Rd

4033 East Southport Rd Indianapolis IN
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $64 total per night from Nov 11 to Nov 12
$64 total
Nov 11 - Nov 12
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Opens in a new windowSuper 8 by Wyndham Indianapolis/Southport Rd
Hilton Garden Inn Indianapolis South/Greenwood

Hilton Garden Inn Indianapolis South/Greenwood

5255 Noggle Way Indianapolis IN
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Nov 22 to Nov 23
$138 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
Opens in a new windowHilton Garden Inn Indianapolis South/Greenwood
Motel 6 Indianapolis, IN - Southport

Motel 6 Indianapolis, IN - Southport

4345 Southport Crossing Way Indianapolis IN
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $80 total per night from Nov 9 to Nov 10
$80 total
Nov 9 - Nov 10
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
Opens in a new windowMotel 6 Indianapolis, IN - Southport
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in South Indianapolis

5 star hotels in South Indianapolis

South Indianapolis Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the South Indianapolis luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in South Indianapolis to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in South Indianapolis will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in South Indianapolis, and plan your next opulent escape.


South Indianapolis hotels essential information

Accommodation
2,630 hotels
Lowest Price
$64
Highest Price
$256
Popular hotels
Country Inn & Suites by Radisson, Indianapolis South, IN, Comfort Inn Indianapolis South I-65, Baymont by Wyndham Indianapolis South, La Quinta Inn & Suites by Wyndham Indianapolis South, Super 8 by Wyndham Indianapolis/Southport Rd, Red Roof Inn Indianapolis South, Hilton Garden Inn Indianapolis South/Greenwood, Motel 6 Indianapolis, IN - Southport

Popular Luxury Stays in South Indianapolis

Recent South Indianapolis Hotel Reviews By Fellow Wanderers