Sikeston Vacation Packages 2026 from $405

Sikeston flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Motel 6 Rolla, MO

$405

per person

Sep 11 - Sep 18

found 20 hours ago

Roundtrip flight included

Cleveland (CLE) to St. Louis (STL)

A restaurant, free self parking, and a 24-hour front desk are among this motel's amenities. WiFi in public areas is free. A snack bar/deli is also provided.

Hermann Grain Bins BNB

Save 100% on your flight

$1,290

per person

Sep 11 - Sep 18

found 20 hours ago

Roundtrip flight included

Cleveland (CLE) to St. Louis (STL)

This bed & breakfast features free WiFi in public areas, barbecue grills, and free self parking. Enjoy the free full breakfast each morning. A garden and a picnic area are also provided.

The Wildwood Hotel

$587

per person

Aug 28 - Aug 31

found 23 hours ago

Roundtrip flight included

Los Angeles (LAX) to St. Louis (STL)

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.

Super 8 by Wyndham Cuba

$439

per person

Sep 11 - Sep 18

found 20 hours ago

Roundtrip flight included

Cleveland (CLE) to St. Louis (STL)

This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business center. A picnic area, a computer station, and laundry facilities are also on offer.

Super 8 by Wyndham Rolla

$408

per person

Sep 11 - Sep 18

found 20 hours ago

Roundtrip flight included

Cleveland (CLE) to St. Louis (STL)

This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business center. Enjoy the indoor pool and conveniences like a 24-hour front desk and laundry facilities.

Top Sikeston hotels deals

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

Free Cancellation

Reserve now, pay when you stay

$111 nightly

$128 total

Jul 28 - Jul 29

Total with taxes and fees

This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and free perks like buffet breakfast and free self parking.

Pool

Breakfast included

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

Free Cancellation

Reserve now, pay when you stay

$91 nightly

$104 total

Jul 26 - Jul 27

Total with taxes and fees

This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. A 24-hour business center, a grocery/convenience store, and express check-out are also on offer.

Pool

Breakfast included

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

Free Cancellation

Reserve now, pay when you stay

$67 nightly

$77 total

Aug 9 - Aug 10

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the 3 onsite conference rooms. Enjoy the gym and conveniences like a 24-hour front desk and laundry facilities.

Breakfast included

Pet friendly

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

Free Cancellation

Reserve now, pay when you stay

$102 nightly

$115 total

Aug 23 - Aug 24

Total with taxes and fees

This hotel features an indoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. A 24-hour business center, a snack bar/deli, and express check-out are also on offer.

Pool

Breakfast included

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO

Free Cancellation

$85 nightly

$96 total

Aug 23 - Aug 24

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Pool

Breakfast included

Fairfield Inn & Suites by Marriott Sikeston

1239 Commerce Drive Sikeston MO

Free Cancellation

Reserve now, pay when you stay

$110 nightly

$125 total

Jul 30 - Jul 31

Total with taxes and fees

This hotel features an indoor pool, a gym, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Relax with a drink at the bar/lounge and enjoy free perks like buffet breakfast and free self parking.

Pool

Breakfast included

Don't see what you're looking for?

See all available properties in Sikeston

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Sikeston attractions

Sikeston Depot Museum

7.6/10 (57 reviews)

You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.

See properties

Frequently asked questions

How much are vacation packages to Sikeston?

Starting from as little as $405, flight and hotel packages are a fabulous way to make your travel budget stretch further. Sikeston, here you come!

How long should my Sikeston vacation be?

Generally, visitors stay 2 nights in Sikeston. Although, that might not be enough time for you. If you aim to explore some of the region's hidden treasures, why not add another few nights to your travel schedule?

Where can I get the best vacation package deals for Sikeston?

With around 400 airlines and 1,000,000 hotels across the world, it's hard to beat Travelocity. Make the most of our impressive range and create your dream Sikeston vacation package. Don't you love it when planning a trip is that easy?

Why should I purchase my Sikeston vacation bundle via Travelocity?

You'll not only enjoy big savings, but you can also access our 24/7 customer support, high-quality service and a Price Match Guarantee. Journey across the globe, discover hidden gems and make lifelong memories — we'll take care of the important details.

Can I save money on my Sikeston car rental if I book it with my hotel or flight?

Absolutely — combine your flight, hotel and car into a Sikeston vacation package and you can save a tidy sum. With so much to see and do in the Sikeston area, that rental car will come in handy. Once you've buckled yourself in, turn up the stereo and make your way to Orpheum Theatre, a famous sight roughly 120 mi from Sikeston.

Which airport is best for Sikeston?

Many vacationers arrive at Cape Girardeau Municipal Airport (CGI). After you've landed and grabbed your luggage, you'll need to head 25 mi south to reach downtown Sikeston. Barkley Regional Airport (PAH) is another option, 45 mi from the center of the city.

What is there to do in Sikeston?

There's an undeniable magic as you wander the streets of Sikeston. The Book Bug and Central Park are just a couple of famous sights that make this city such a sought-after destination, so put them at the top of your travel itinerary.

Where should I stay when visiting Sikeston?

The Pear Tree Inn Sikeston is recommended by many visitors. Book as soon as possible to avoid missing out.

Where to stay in Sikeston: Best areas for travelers

Miner: If you're in the mood for some sightseeing in this neighborhood, head straight for The Book Bug. It's just one reason many visitors stay here. We suggest checking out the rates and reviews of the Drury Inn & Suites Sikeston, MO, the Motel 6 Sikeston MO and the Pear Tree Inn Sikeston.
Charleston: This is a great neighborhood for your next getaway — not the busiest place around, but still highly rated by many travelers. For an enjoyable stay, make a reservation at the Quality Inn Charleston I-57 or the Super 8 by Wyndham Charleston MO.