Hotels with Restaurants in Santee from $68
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Top Santee Hotels with Restaurants
Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
$134 nightly
The price is $149 total per night
$149 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business ...
Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
Free Cancellation
Reserve now, pay when you stay
$118 nightly
The price is $131 total per night
$131 total
Dec 30 - Dec 31
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Holiday Inn Santee by IHG
139 Bradford Blvd Santee SC
Free Cancellation
$108 nightly
The price is $120 total per night
$120 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Comfort Inn & Suites Santee
221 Britain St Santee SC
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $114 total per night
$114 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
Baymont by Wyndham Santee
249 Britain Street Santee SC
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $89 total per night
$89 total
Dec 25 - Dec 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
Travelodge by Wyndham Santee
9117 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
$61 nightly
The price is $68 total per night
$68 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Free self parking is available and the hotel's front desk is staffed around-the-clock. Guests will appreciate free perks like continental breakfast and WiFi ...
Super 8 by Wyndham Santee
9125 Old Highway 6 Santee SC
Free Cancellation
Reserve now, pay when you stay
$75 nightly
The price is $83 total per night
$83 total
Dec 25 - Dec 26
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $78 total per night
$78 total
Dec 25 - Dec 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Econo Lodge
9112 Old 6 Highway Santee SC
Free Cancellation
Reserve now, pay when you stay
$63 nightly
The price is $70 total per night
$70 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, luggage storage, and barbecue grills are also on offer.
Ramada by Wyndham Santee I-95
123 Mall Street Santee SC
$80 nightly
The price is $88 total per night
$88 total
Dec 30 - Dec 31
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santee hotels essential information
Accommodation | 305 hotels |
|---|---|
Lowest Price | $68 |
Highest Price | $149 |
Popular hotels | Best Western Plus Santee Inn, Hampton Inn Santee-I-95, Holiday Inn Santee by IHG, Red Roof Inn Santee, Comfort Inn & Suites Santee, Baymont by Wyndham Santee, Super 8 by Wyndham Santee, Travelodge by Wyndham Santee, Econo Lodge, Ramada by Wyndham Santee I-95 |
Recent Santee hotel reviews by fellow wanderers
Best Western Plus Santee Inn
5 out of 5
Posted 5 days ago
Travelocity Verified Review
"The staff makes you feel at home. And the place is spotless."
A verified traveler stayed at Best Western Plus Santee Inn
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