Book Hotels in Santa Rosa
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Santa Rosa hotels

The Executive Hotel
Calle 52 Panama City Panama
Fully refundable
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Good customer service
Reviewed on Feb 13, 2026

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $133 total per night from Mar 3 to Mar 4
$133 total
Mar 3 - Mar 4
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Awesome stay without any issues. Very friendly staff throughout the entire Hotel.
Reviewed on Feb 16, 2026

W Panama
Calle Aquilino de la Guardia & Calle 50 Panama City
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $202 total per night from Mar 7 to Mar 8
$202 total
Mar 7 - Mar 8
Total with taxes and fees
This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the ...
Room
Reviewed on Feb 10, 2026

Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Feb 19 to Feb 20
$109 total
Feb 19 - Feb 20
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
Staff was friendly, room was clean and for the price, it was worth it.
Reviewed on Feb 12, 2026

Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $243 total per night from Mar 7 to Mar 8
$243 total
Mar 7 - Mar 8
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
Staff was friendly and helpful. Amenities were great and location was perfect.
Reviewed on Feb 10, 2026

Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $194 total per night from Feb 25 to Feb 26
$194 total
Feb 25 - Feb 26
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Well managed luxury hotel
Reviewed on Feb 10, 2026

Principe Hotel and Suites
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $58 total per night from Feb 26 to Feb 27
$58 total
Feb 26 - Feb 27
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Amazing staff, very helpfull.
Reviewed on Feb 12, 2026

Sheraton Grand Panama
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from Feb 27 to Feb 28
$148 total
Feb 27 - Feb 28
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
Beautiful hotel the only one I stayed at when I was in Panama that provided washcloths. Was very clean. Things were a little more expensive here, but I could see why very good breakfast buffet.
Reviewed on Feb 16, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Feb 23 to Feb 24
$119 total
Feb 23 - Feb 24
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
The room was cleaned every day, but the bathtub is very old and nasty because there's so much filth accumulated that it can't be removed no matter what they do Room service and front desk was outstanding and very patient I will book my next stay in Panamá right here
Reviewed on Feb 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Santa Rosa hotel reviews by fellow wanderers

Hotel Riu Plaza Panama
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Awesome stay without any issues. Very friendly staff throughout the entire Hotel."
A verified traveler stayed at Hotel Riu Plaza Panama
Explore More Ways to Travel with Travelocity
- Hotels near Gamboa Rainforest Resort
- Castles in Maria Chiquita
- Adults Only Resorts & in Maria Chiquita
- Hotels with Pools in Maria Chiquita
- Maria Chiquita Hotels
- Limón Hotels
- Hotels near Colon Free Zone
- Mechi Hotels
- Apartments in Gamboa
- Hostels in Gamboa
- Hotel Wedding Venues Hotels in Gamboa
- Gamboa Hotels
- Cativa Hotels
- Hotels near Playa La Angosta
- Portobelo Hotels
- Fort Sherman Hotels
- Rio Gatun Hotels
- Lodges in Buena Vista
- All Inclusive Resorts & in Colón
- Beach Resorts & in Colón
- Colón Hotels
- 3 Star Hotels in Colon
- 4 Star Hotels in Colon
- B&B in Colon
- Hostels in Colon
- Adults Only Resorts & in Colon
- All Inclusive Resorts & in Colon
- Beach Resorts & in Colon
- Historic Hotels in Colon
- Hotels with Restaurants in Colon
- Oceanfront Hotels in Colon
- Pet Friendly Hotels in Colon
- Hotel Wedding Venues Hotels in Colon
- Colon Hotels
- Motels in Colon
- Vacation Homes in Colon
- Resorts in Colon
- Villas in Colon
- Sabanitas Hotels
- Buenaventura Hotels






