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Top hotels in Santa Cruz

Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

4 out of 5
Calle Farnesio 6 Seville Seville
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $186 total per night from Jun 14 to Jun 15
$186 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Enjoy the a rooftop terrace and perks like free WiFi. Self parking, a coffee shop, and ...
"What a beautiful hotel, well maintained with mozart’s music playing in the background! Loved it!"

Reviewed on May 19, 2026

Opens in a new windowHotel Amadeus Sevilla
Hotel Rey Alfonso X

Hotel Rey Alfonso X

4 out of 5
Calle Ximenez De Enciso, 35 Seville Seville
$187 nightly
The price is $205 total per night from Jun 7 to Jun 8
$205 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a restaurant, a seasonal outdoor pool, and a bar/lounge. Enjoy the a rooftop terrace and perks like free WiFi. There's a poolside bar on ...
"Hotel location is super convenient and breakfast menu is very good for us to have many choices."

Reviewed on May 19, 2026

Opens in a new windowHotel Rey Alfonso X
Hotel Murillo Reinoso

Hotel Murillo Reinoso

2 out of 5
Lope de Rueda, 16 Seville Seville
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Jun 10 to Jun 11
$135 total
Jun 10 - Jun 11
Total with taxes and fees
An outdoor pool is featured at this hotel, along with free WiFi in public areas and a garden. Dry cleaning, luggage storage, and concierge services are also ...
"Ideally located for all the main attractions. The staff were friendly and helpful. Isabel was especially accommodating. Would highly recommend the hotel."

Reviewed on May 19, 2026

Opens in a new windowHotel Murillo Reinoso
Hotel Fernando III

Hotel Fernando III

4 out of 5
San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $195 total per night from Jun 18 to Jun 19
$195 total
Jun 18 - Jun 19
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
"Great location and lovely clean hotel"

Reviewed on May 17, 2026

Opens in a new windowHotel Fernando III
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

4 out of 5
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $186 total per night from May 31 to Jun 1
$186 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a full-service spa and a seasonal outdoor pool. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...
"Fabulous location. Nice, spacious rooms but dated interior - could do with some minor updates to guest rooms (we had three for comparison). The rooftop bar, hotel employees and location can’t be beat. Wonderful place!"

Reviewed on May 19, 2026

Opens in a new windowLas Casas de la Judería, Sevilla Historic City Center
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

5 out of 5
San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
$670 nightly
The price is $737 total per night from Jun 3 to Jun 4
$737 total
Jun 3 - Jun 4
Total with taxes and fees
This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...
"The breakfast bar offered a nice selection of foods. For dinner, I had the best Flan I’ve ever eaten"

Reviewed on May 17, 2026

Opens in a new windowHotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Doña Maria

Hotel Doña Maria

4 out of 5
Don Remondo 19 Seville Seville
Fully refundableReserve now, pay when you stay
$177 nightly
The price is $195 total per night from Jun 17 to Jun 18
$195 total
Jun 17 - Jun 18
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and a seasonal outdoor pool. Enjoy the a rooftop terrace and perks like free WiFi. A coffee shop, a terrace, ...
"We loved the location even though it was very far from parking. The internet was terrible and I worked from the lobby, but the staff was accommodating and being steps from the cathedral was very special. The place is like a museum!"

Reviewed on May 19, 2026

Opens in a new windowHotel Doña Maria
Hotel Murillo

Hotel Murillo

2 out of 5
Calle Lope de Rueda, 7-9 Seville Seville
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Jun 7 to Jun 8
$93 total
Jun 7 - Jun 8
Total with taxes and fees
A rooftop terrace is featured at this hotel, along with free WiFi in public areas and a library. Families will appreciate the onsite laundry facilities and babysitting. ...
"Nice hotel in a great location . Definitely I will return."

Reviewed on May 19, 2026

Opens in a new windowHotel Murillo
EME Catedral Mercer Hotel

EME Catedral Mercer Hotel

5 out of 5
Calle Alemanes 27 Seville Seville
Fully refundableReserve now, pay when you stay
$224 nightly
The price is $247 total per night from Jun 15 to Jun 16
$247 total
Jun 15 - Jun 16
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Enjoy the gym and perks like free WiFi. Enjoy the a rooftop ...
"This was my second time staying at EME Catedral, and funny enough, I was assigned the exact same room as my previous stay, which made the experience feel oddly familiar in a nice way. The location remains unbeatable, and the hotel still has that stylish atmosphere that makes it such a great option ..."

Reviewed on May 17, 2026

Opens in a new windowEME Catedral Mercer Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Cruz Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Santa Cruz area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Santa Cruz to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Santa Cruz are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Santa Cruz hotel reviews by fellow wanderers

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