Book Hotels in Santa Clara

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Top Santa Clara hotels

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Jan 2 to Jan 3
$119 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Breakfast is the best part. Hotel is dated and needs a refresh. The staff are ok and you get the impression they are lazy unless the boss is around

Reviewed on Dec 6, 2025

Opens in a new windowPlaza Paitilla Inn Hotel
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $135 total per night from Dec 15 to Dec 16
$135 total
Dec 15 - Dec 16
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Excellence.

Reviewed on Dec 7, 2025

Opens in a new windowHotel Riu Plaza Panama
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $156 total per night from Dec 12 to Dec 13
$156 total
Dec 12 - Dec 13
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
This hotel accommodated my husband and I at the last minute. Due to the prior booking we had to relocate. The staff was friendly and helpful. The location was a bit further from Panama City then we would like. But we were grateful to find somewhere to stay due to it being a 3-day holiday. Would definitely ...

Reviewed on Dec 9, 2025

Opens in a new windowMarriott Panama Hotel
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $175 total per night from Jan 9 to Jan 10
$175 total
Jan 9 - Jan 10, 2026
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center ...
clean and new rooms, the customer service was perfect.

Reviewed on Dec 9, 2025

Opens in a new windowLas Americas Golden Tower Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $198 total per night from Dec 16 to Dec 17
$198 total
Dec 16 - Dec 17
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
I loved everything about my stay

Reviewed on Nov 29, 2025

Opens in a new windowWaldorf Astoria Panama
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $55 total per night from Dec 27 to Dec 28
$55 total
Dec 27 - Dec 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Great hotel, location, food. Highly recommend the sushi restaurant next door.. One of the best ever.

Reviewed on Dec 2, 2025

Opens in a new windowPrincipe Hotel and Suites
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $144 total per night from Dec 18 to Dec 19
$144 total
Dec 18 - Dec 19
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
Front desk people and their Amenities are amazing!

Reviewed on Dec 7, 2025

Opens in a new windowMegapolis Hotel Panamá
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $193 total per night from Dec 19 to Dec 20
$193 total
Dec 19 - Dec 20
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and 4 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. There's ...
Nice enough place. Westin is always reliable.

Reviewed on Dec 3, 2025

Opens in a new windowThe Westin Playa Bonita Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$272 nightly
The price is $272 total per night from Dec 19 to Dec 20
$272 total
Dec 19 - Dec 20
Total with taxes and fees
A full-service spa, a nightclub, and 4 outdoor pools are all featured at this all-inclusive property. Spend a day at the beach kayaking, or relax with free beach ...
Everything was great especially the view and food

Reviewed on Dec 8, 2025

Opens in a new windowDreams Playa Bonita Panama - All Inclusive
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Clara?
Take some of the trials out of traveling with kids by booking a family-friendly Santa Clara hotel. From thoughtful amenities to more services, these stays come with perks that'll help make your getaway run like a dream: Jungle Land Panama Lodge will help make your getaway the best one yet. It offers a host of conveniences geared toward families, such as complimentary breakfast and a picnic area. Otherwise, spend your nights in Santa Clara at Casa en Gamboa al lado Canal de Panama. Make the most of a nearby beach, a beach shuttle and more here.
Where can I find cheap hotels in Santa Clara?
At Travelocity you'll find really nice hotels in Santa Clara at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Clara rather than in Santa Clara. We may find you even better rates, too.
How do I find the best Santa Clara hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Clara then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Clara?
The cheapest hotel in Santa Clara is $55. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Clara?
There are 1,682 hotels in Santa Clara on Travelocity.
What are the best hotels in Santa Clara?
Santa Clara has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Clara for you!
When is the best time to visit Santa Clara?
If you want the joy of a fun-filled trip in peak season, visit Santa Clara during February, March and April. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, October and December.
When is the cheapest time to stay in Santa Clara?
Based on historic data is usually the cheapest month to visit Santa Clara. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Clara?
There are multiple hotels in Santa Clara that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Clara. We have plenty of kid-friendly hotels in Santa Clara to choose from on Travelocity!
Why book a hotel in Santa Clara through Travelocity?
Because we have the top hotels in Santa Clara! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Clara on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Clara hotel reviews by fellow wanderers

Marriott Panama Hotel

Marriott Panama Hotel

5 out of 5
Posted 17 hours ago
Travelocity Verified Review
"This hotel accommodated my husband and I at the last minute. Due to the prior booking we had to relocate. The staff was friendly and helpful. The location was a bit further from Panama City then we would like. But we were grateful to find somewhere to stay due to it being a 3-day holiday. Would definitely stay there again. Everything you need is in this one location."
A verified traveler stayed at Marriott Panama Hotel
Marriott Panama Hotel

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