Book Hotels in Santa Clara

Start date: Check-in selected.
To Date
End date: Check-out

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top Santa Clara hotels

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $126 total per night from Nov 9 to Nov 10
$126 total
Nov 9 - Nov 10
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Great hotel for the price. Nice pool and the included breakfast was a plus. It was clean and staff was nice except for the service desk who appeared to be annoyed with me asking for wash cloths everyday since they failed at leaving any or not enough for me and my daughter. Other than that I had no ...

Reviewed on Oct 20, 2025

Opens in a new windowHotel Riu Plaza Panama
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from Nov 7 to Nov 8
$148 total
Nov 7 - Nov 8
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
Great service and property

Reviewed on Oct 21, 2025

Opens in a new windowMarriott Panama Hotel
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Plaza de la Independencia Casco Viejo, Panama City, Panama
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $217 total per night from Oct 26 to Oct 27
$217 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in ...
Great hotel, clean, pretty , located right in the middle of Old Panama. Great experience. Staff more than friendly

Reviewed on Oct 20, 2025

Opens in a new windowCentral Hotel Panama Casco Viejo
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $198 total per night from Nov 1 to Nov 2
$198 total
Nov 1 - Nov 2
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
Upon arrival to the Waldorf, Edgar was right there to assist us with our luggage to the room. It was at that moment I knew the W.A. hospitality was about to be extraordinary.

Reviewed on Oct 22, 2025

Opens in a new windowWaldorf Astoria Panama
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina, Panama City, Panama
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $55 total per night from Nov 9 to Nov 10
$55 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
The staff was very helpful and accommodating. There’s a 24/7 convenience store next door. My room was clean and looked just like the photos. Only thing was laggy WiFi and I really wish they put a mini fridge in the rooms. Other than that, perfect for my short stay.

Reviewed on Oct 22, 2025

Opens in a new windowPrincipe Hotel and Suites
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50, Bella Vista, Panama City
Fully refundableReserve now, pay when you stay
$191 nightly
The price is $210 total per night from Nov 7 to Nov 8
$210 total
Nov 7 - Nov 8
Total with taxes and fees
This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the ...
Will stay again.

Reviewed on Oct 20, 2025

Opens in a new windowW Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $138 total per night from Nov 9 to Nov 10
$138 total
Nov 9 - Nov 10
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
Good

Reviewed on Oct 23, 2025

Opens in a new windowMegapolis Hotel Panamá
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5 out of 5
Km 6 Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $183 total per night from Nov 5 to Nov 6
$183 total
Nov 5 - Nov 6
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and 4 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. There's ...
Staff was very nice and helpful.

Reviewed on Oct 23, 2025

Opens in a new windowThe Westin Playa Bonita Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
$290 nightly
The price is $290 total per night from Nov 18 to Nov 19
$290 total
Nov 18 - Nov 19
Total with taxes and fees
A full-service spa, a nightclub, and 4 outdoor pools are all featured at this all-inclusive property. Spend a day at the beach kayaking, or relax with free beach ...
Had a great stay. I would definitely recommend it to others. On the downside, the rooms could use an upgrade and cleaning of the rooms could be better.

Reviewed on Oct 21, 2025

Opens in a new windowDreams Playa Bonita Panama - All Inclusive
Don't see what you're looking for?
See all available properties in Santa Clara
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Clara?
Take some of the trials out of traveling with kids by booking a family-friendly Santa Clara hotel. From thoughtful amenities to more services, these stays come with perks that'll help make your getaway run like a dream: Jungle Land Panama Lodge will help make your getaway the best one yet. It offers a host of conveniences geared toward families, such as complimentary breakfast and a picnic area. Otherwise, spend your nights in Santa Clara at Casa en Gamboa al lado Canal de Panama. Make the most of a nearby beach, a beach shuttle and more here.
Where can I find cheap hotels in Santa Clara?
At Travelocity you'll find really nice hotels in Santa Clara at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Clara rather than in Santa Clara. We may find you even better rates, too.
How do I find the best Santa Clara hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Clara then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Clara?
The cheapest hotel in Santa Clara is $55. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Clara?
There are 1,523 hotels in Santa Clara on Travelocity.
What are the best hotels in Santa Clara?
Santa Clara has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Clara for you!
When is the best time to visit Santa Clara?
If you want the joy of a fun-filled trip in peak season, visit Santa Clara during February, March and April. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, October and December.
When is the cheapest time to stay in Santa Clara?
Based on historic data is usually the cheapest month to visit Santa Clara. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Clara?
There are multiple hotels in Santa Clara that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Clara. We have plenty of kid-friendly hotels in Santa Clara to choose from on Travelocity!
Why book a hotel in Santa Clara through Travelocity?
Because we have the top hotels in Santa Clara! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Clara on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Clara hotel reviews by fellow wanderers