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Top Santa Clara hotels

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
$172 nightly
The price is $192 total per night from Aug 29 to Aug 30
$192 total
Aug 29 - Aug 30
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in ...
"Clean rooms"

Reviewed on Jul 28, 2026

Opens in a new windowCentral Hotel Panama Casco Viejo
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $136 total per night from Aug 25 to Aug 26
$136 total
Aug 25 - Aug 26
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"My stay was excellent"

Reviewed on Jul 29, 2026

Opens in a new windowHotel Riu Plaza Panama
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $62 total per night from Jul 30 to Jul 31
$62 total
Jul 30 - Jul 31
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
"It’s more like a stop over place , near to the metro station, it’s in a good location tho, accessible to grocery store as well."

Reviewed on Jul 29, 2026

Opens in a new windowPrincipe Hotel and Suites
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
$208 nightly
The price is $229 total per night from Jul 30 to Jul 31
$229 total
Jul 30 - Jul 31
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
"It’s was bad"

Reviewed on Jul 27, 2026

Opens in a new windowMegapolis Hotel Panamá
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $124 total per night from Aug 10 to Aug 11
$124 total
Aug 10 - Aug 11
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
"Good"

Reviewed on Jul 27, 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$255 nightly
The price is $255 total per night from Jul 30 to Jul 31
$255 total
Jul 30 - Jul 31
Total with taxes and fees
This all-inclusive property features a full-service spa, a nightclub, and 7 restaurants. Spend a day at the beach kayaking, or relax with free beach cabanas ...
"The room was quite clean visibly, but there was a musty smell. The staff were always kind and helpful. To top it off, breakfast was delicious!"

Reviewed on Jul 28, 2026

Opens in a new windowDreams Playa Bonita Panama - All Inclusive
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$275 nightly
The price is $303 total per night from Aug 29 to Aug 30
$303 total
Aug 29 - Aug 30
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
Opens in a new windowWaldorf Astoria Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $116 total per night from Aug 1 to Aug 2
$116 total
Aug 1 - Aug 2
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Relax with a drink at the bar/lounge and enjoy free ...
Opens in a new windowWaymore Hotel Spa & Casino
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $130 total per night from Aug 8 to Aug 9
$130 total
Aug 8 - Aug 9
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowCourtyard by Marriott Panama Multiplaza Mall
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Clara?
Take some of the trials out of traveling with kids by booking a family-friendly Santa Clara hotel. From thoughtful amenities to more services, these stays come with perks that'll help make your getaway run like a dream: Jungle Land Panama Lodge will help make your getaway the best one yet. It offers a host of conveniences geared toward families, such as complimentary breakfast and a picnic area. Otherwise, spend your nights in Santa Clara at Casa en Gamboa al lado Canal de Panama. Make the most of a nearby beach, a beach shuttle and more here.
Where can I find cheap hotels in Santa Clara?
At Travelocity you'll find really nice hotels in Santa Clara at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Clara rather than in Santa Clara. We may find you even better rates, too.
How do I find the best Santa Clara hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Clara then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Clara?
The cheapest hotel in Santa Clara is $62. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Clara?
There are 1,788 hotels in Santa Clara on Travelocity.
What are the best hotels in Santa Clara?
Santa Clara has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Clara for you!
When is the best time to visit Santa Clara?
If you want the joy of a fun-filled trip in peak season, visit Santa Clara during February, March and April. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, October and December.
When is the cheapest time to stay in Santa Clara?
Based on historic data is usually the cheapest month to visit Santa Clara. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Clara?
There are multiple hotels in Santa Clara that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Clara. We have plenty of kid-friendly hotels in Santa Clara to choose from on Travelocity!
Why book a hotel in Santa Clara through Travelocity?
Because we have the top hotels in Santa Clara! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Clara on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Clara hotel reviews by fellow wanderers

Principe Hotel and Suites

Principe Hotel and Suites

5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"It’s more like a stop over place , near to the metro station, it’s in a good location tho, accessible to grocery store as well."
A verified traveler stayed at Principe Hotel and Suites
Principe Hotel and Suites