Book Hotels in Santa Clara

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Top Santa Clara hotels

The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
Fully refundable
$82 nightly
The price is $90 total per night from Feb 20 to Feb 21
$90 total
Feb 20 - Feb 21
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Great location and the staff was really accommodating

Reviewed on Jan 25, 2026

Opens in a new windowThe Executive Hotel
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $151 total per night from Feb 8 to Feb 9
$151 total
Feb 8 - Feb 9
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Hotel and rooms where keep clean. The staff was very nice and welcoming

Reviewed on Jan 23, 2026

Opens in a new windowHotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $243 total per night from Feb 21 to Feb 22
$243 total
Feb 21 - Feb 22
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
awesome location, great staff

Reviewed on Jan 12, 2026

Opens in a new windowWaldorf Astoria Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $154 total per night from Feb 15 to Feb 16
$154 total
Feb 15 - Feb 16
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center ...
Good place to stay for medical services as Paitilla Medical Center, Paitilla Hospital and Royal Center Medical Offices are all within 5 minutes walking. Sushi restaurant on the entry level is excellent.

Reviewed on Jan 18, 2026

Opens in a new windowLas Americas Golden Tower Panama
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
Fully refundableReserve now, pay when you stay
$207 nightly
The price is $228 total per night from Feb 7 to Feb 8
$228 total
Feb 7 - Feb 8
Total with taxes and fees
This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the ...
Suite was spacious, clean, and the staff was exceptional.

Reviewed on Jan 16, 2026

Opens in a new windowW Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $95 total per night from Feb 3 to Feb 4
$95 total
Feb 3 - Feb 4
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
The room was kept so clean daily and the location was easy for day tours to pick me up from The hotel floors were quiet and so clean and always smelt delicious

Reviewed on Jan 20, 2026

Opens in a new windowWaymore Hotel Spa & Casino
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from Feb 13 to Feb 14
$148 total
Feb 13 - Feb 14
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
Great staff

Reviewed on Jan 15, 2026

Opens in a new windowSheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Feb 2 to Feb 3
$119 total
Feb 2 - Feb 3
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
All very good and great value! Great location too.

Reviewed on Jan 12, 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$432 nightly
The price is $432 total per night from Feb 24 to Feb 25
$432 total
Feb 24 - Feb 25
Total with taxes and fees
A full-service spa, a nightclub, and 4 outdoor pools are all featured at this all-inclusive property. Spend a day at the beach kayaking, or relax with free beach ...
Everything was great very relaxing hotel staff very nice.

Reviewed on Jan 21, 2026

Opens in a new windowDreams Playa Bonita Panama - All Inclusive
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Santa Clara?
Take some of the trials out of traveling with kids by booking a family-friendly Santa Clara hotel. From thoughtful amenities to more services, these stays come with perks that'll help make your getaway run like a dream: Jungle Land Panama Lodge will help make your getaway the best one yet. It offers a host of conveniences geared toward families, such as complimentary breakfast and a picnic area. Otherwise, spend your nights in Santa Clara at Casa en Gamboa al lado Canal de Panama. Make the most of a nearby beach, a beach shuttle and more here.
Where can I find cheap hotels in Santa Clara?
At Travelocity you'll find really nice hotels in Santa Clara at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Santa Clara rather than in Santa Clara. We may find you even better rates, too.
How do I find the best Santa Clara hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Santa Clara then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Santa Clara?
The cheapest hotel in Santa Clara is $90. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Santa Clara?
There are 1,697 hotels in Santa Clara on Travelocity.
What are the best hotels in Santa Clara?
Santa Clara has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Santa Clara for you!
When is the best time to visit Santa Clara?
If you want the joy of a fun-filled trip in peak season, visit Santa Clara during February, March and April. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, October and December.
When is the cheapest time to stay in Santa Clara?
Based on historic data is usually the cheapest month to visit Santa Clara. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Santa Clara?
There are multiple hotels in Santa Clara that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Santa Clara. We have plenty of kid-friendly hotels in Santa Clara to choose from on Travelocity!
Why book a hotel in Santa Clara through Travelocity?
Because we have the top hotels in Santa Clara! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Santa Clara on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Santa Clara hotel reviews by fellow wanderers