Book Hotels in Panacea, FL
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Top Panacea hotels

New Listing! Waterfront, Tiki Hut, Elevator
Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
Quiet and relaxing! A great place on the canal !
Reviewed on Jul 27, 2025

Secluded Florida Beach Bungalow-best of both worlds-BEACH TIME & FISHING TIME!!
Panacea FL
$364 nightly
The price is $397 total per night from Apr 26 to Apr 27
$397 total
Apr 26 - Apr 27
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
Loved the cottage. Only drawback is the seclusion. I’m sure in the busy season things are livelier. But we were looking for quiet and that’s what we got!
Reviewed on Mar 24, 2026

Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.
Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
This was a nice relaxing stay. The area including the beaches is quiet. The house was perfect right on the water and had everything we needed. The hosts were very helpful leading up to our stay giving us some information on the area. We hope to be able to come stay again.
Reviewed on Apr 8, 2026

Beautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis
Alligator Point FL
This vacation home features an outdoor pool and a hot tub. Laundry facilities and barbecue grills are also provided.
This was our 2nd stay and we will be back. This completely renovated townhome provides a luxurious and relaxing environment. Perfect waterfront location and fantastic Host! Heather was very responsive and provided an extensive list of local resources, restaurants, activities and events in the area. ...
Reviewed on Apr 12, 2026

Hideaway Beach Cottage on waterfront with amazing views.
Panacea FL
This cottage features a garden, laundry facilities, and barbecue grills.
Everything about ours stay was absolutely amazing! We had a group of four, one being in a wheelchair. The house was completely accessible to her except for the bathtub. However she could get in there and we used a shower chair. She was even able to put her feet in the water at the beach. The cottage ...
Reviewed on Apr 10, 2026

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch
Panacea FL
This vacation home features a garden, laundry facilities, and barbecue grills.
The sunrise from this porch is breath taking. The house is well equipped and the the porch is simply amazing. Host was quick to respond and we will be renting this home again!
Reviewed on Dec 19, 2025

Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations
Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
Our second stay at the house and will return again. A wonderful place to be on the beach.
Reviewed on Apr 12, 2026

Best deal at Alligator Point
Alligator Point FL
This vacation home includes a garden and laundry facilities.
We found the house extremely clean and the host was very helpful with fishing tips and suggestions for nearby restaurants!Spectacular views of the water and our pup really enjoyed the fenced yard!
Reviewed on Apr 11, 2026

The Panacea Motel
1545 Coastal Hwy Panacea FL
$111 nightly
The price is $124 total per night from May 13 to May 14
$124 total
May 13 - May 14
Total with taxes and fees
Stay at this motel in Panacea. Enjoy free WiFi, free parking, and hiking/biking on site. Popular attractions Panacea Springs and Woolley Park are located ...
This property is retro and fun. 1950-60's style is well done. No frills, but adequate amenities. Was there for the Worm Gruntin' Festival and found a plastic worm placed on the car windshield. Cool touch!
Reviewed on Apr 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Panacea hotel reviews by fellow wanderers

The Panacea Motel
4 out of 5
Posted 10 hours ago
Travelocity Verified Review
"This property is retro and fun. 1950-60's style is well done. No frills, but adequate amenities. Was there for the Worm Gruntin' Festival and found a plastic worm placed on the car windshield. Cool touch!"
A verified traveler stayed at The Panacea Motel
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