Book Hotels in Panacea, FL

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Top Panacea hotels

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

Alligator Point
$1,799 nightly
The price is $1,964 total per night from Nov 18 to Nov 19
$1,964 total
Nov 18 - Nov 19
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
Love this house! Plenty of beds, great views and the house was stocked as well as I’ve ever seen in a rental property (I’m serious!!!). Thank you!

Reviewed on Oct 12, 2025

Opens in a new window7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!

NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!

Panacea
A hot tub is featured at this vacation home, along with laundry facilities and barbecue grills.
This property was perfect. So fresh and awesome views. The best mattresses and pillows we have slept on in a long time. Very pet friendly. Great place to walk my dog. Wonderful kitchen.

Reviewed on Oct 19, 2025

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Opens in a new windowNEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!
PRIVATE LUXURY BEACHFRONT HOME!

PRIVATE LUXURY BEACHFRONT HOME!

Alligator Point
This vacation home featured laundry facilities and barbecue grills.
Great house. Great view.

Reviewed on Oct 25, 2025

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Opens in a new windowPRIVATE LUXURY BEACHFRONT HOME!
5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

Panacea
This vacation home features a garden, laundry facilities, and barbecue grills.
The property was absolutely wonderful!! The host communications was very responsive and timely. I would definitely recommend to anyone and would book again if ever in the area. My overall experience was a 5 out of 5!!!

Reviewed on Oct 26, 2025

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Opens in a new window5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch
"Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8

"Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8

Alligator Point
This vacation home features a garden, laundry facilities, and barbecue grills.
This is our 2nd time visiting. We absolutely love this house and the view!

Reviewed on Nov 5, 2025

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Opens in a new window"Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8
Coastal Getaway on canal-steps to the beach

Coastal Getaway on canal-steps to the beach

Panacea
This vacation home features a garden, laundry facilities, and barbecue grills.
All is good

Reviewed on Oct 27, 2025

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Opens in a new windowCoastal Getaway on canal-steps to the beach
Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

Alligator Point
This vacation home featured laundry facilities and barbecue grills.
Host was very hospitable, quick to respond. and very accommodating. Great views, clean home, amenities are exactly what were advertised. Great theme for a home in a beautiful relaxing area on the gulf. Highly recommend

Reviewed on Nov 11, 2025

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Opens in a new windowTiki House is a Unique Beach Front gathering spot for family, friends and PUPs.
Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Panacea
$363 nightly
The price is $397 total per night from Nov 18 to Nov 19
$397 total
Nov 18 - Nov 19
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
There are so many wonderful things at this property that I hate to say anything bad! But there are maintenance issues that need to be addressed.

Reviewed on Oct 24, 2025

Opens in a new windowSkipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock
The Panacea Motel

The Panacea Motel

2 out of 5
1545 Coastal Hwy, Panacea, FL
$107 nightly
The price is $120 total per night from Nov 23 to Nov 24
$120 total
Nov 23 - Nov 24
Total with taxes and fees
Stay at this motel in Panacea. Enjoy free WiFi, free parking, and hiking/biking on site. Popular attractions Panacea Springs and Woolley Park are located ...
Everything was perfect. It was funky and cool. Loved it.

Reviewed on Nov 9, 2025

Opens in a new windowThe Panacea Motel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Panacea?
Family vacations are where the best memories are made, but it's no secret that traveling with youngsters can be difficult. These kid-friendly Panacea hotels come with perks designed to keep young and old alike comfortable and happy: Put your bags down at Tide Creek Lookout. It comes with a nearby beach, animal viewing activities and a talent for making families feel welcome. Also check out Gated Water View Pool Home on Dickerson Bay. It offers a swimming pool, a travel crib and plenty of opportunities for family time.
Where can I find cheap hotels in Panacea?
At Travelocity you'll find really nice hotels in Panacea at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Panacea rather than in Panacea. We may find you even better rates, too.
How do I find the best Panacea hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Panacea then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Panacea?
The cheapest hotel in Panacea is $120. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Panacea?
There are 502 hotels in Panacea on Travelocity.
What are the best hotels in Panacea?
Panacea has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Panacea for you!
When is the best time to visit Panacea?
If you want the joy of a fun-filled trip in peak season, visit Panacea during February, April and September. If you'd prefer the peace of off-season, book a stay during quieter months, such as July, October and November.
When is the cheapest time to stay in Panacea?
Based on historic data is usually the cheapest month to visit Panacea. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Panacea?
There are multiple hotels in Panacea that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Panacea. We have plenty of kid-friendly hotels in Panacea to choose from on Travelocity!
Why book a hotel in Panacea through Travelocity?
Because we have the top hotels in Panacea! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Panacea on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Panacea hotel reviews by fellow wanderers

Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

5 out of 5
Posted 6 days ago
Travelocity Verified Review
"Host was very hospitable, quick to respond. and very accommodating. Great views, clean home, amenities are exactly what were advertised. Great theme for a home in a beautiful relaxing area on the gulf. Highly recommend "
A verified traveler stayed at Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.
Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

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