Book Hotels in Panacea, FL

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Top Panacea hotels

NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!

NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!

Panacea FL
A hot tub is featured at this vacation home, along with laundry facilities and barbecue grills.
Shawna and John are excellent hosts. They responded immediately to any of our questions. The house is amazing. If you are looking for a quiet and relaxing luxury stay for the whole family. This is your spot.

Reviewed on Dec 14, 2025

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Opens in a new windowNEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!
PRIVATE LUXURY BEACHFRONT HOME!

PRIVATE LUXURY BEACHFRONT HOME!

Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
The location is perfect! It’s close to everything and anywhere you would want to go . The home has a beautiful kitchen space . The beach is steps away from the back door . The views are amazing!! The upstairs balcony is the perfect space to read a book or watch the sunsets .

Reviewed on Dec 16, 2025

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Opens in a new windowPRIVATE LUXURY BEACHFRONT HOME!
"Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8

"Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8

Alligator Point FL
This vacation home features a garden, laundry facilities, and barbecue grills.
This is our 2nd time visiting. We absolutely love this house and the view!

Reviewed on Nov 5, 2025

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Opens in a new window"Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8
5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

Panacea FL
This vacation home features a garden, laundry facilities, and barbecue grills.
The sunrise from this porch is breath taking. The house is well equipped and the the porch is simply amazing. Host was quick to respond and we will be renting this home again!

Reviewed on Dec 19, 2025

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Opens in a new window5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch
Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
We LOVED our stay at the Tiki House. The location is on our favorite part of Alligator Point (Mud Cove). Our son loves to cast the net for the Mullet and Shrimp that come into the Mud Cove area during this time of year. Loved the large kitchen bar that was perfect for our traditional Thanksgiving ...

Reviewed on Dec 2, 2025

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Opens in a new windowTiki House is a Unique Beach Front gathering spot for family, friends and PUPs.
Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock

Panacea FL
$383 nightly
The price is $418 total per night from Jan 3 to Jan 4
$418 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
We really enjoyed our time at Skipper! It's location on the west end of Alligator Point is perfect for walking the beach for miles in either direction. With so many shells to search for and so many dolphins to watch, our time there was so relaxing that we can't wait to go back!

Reviewed on Dec 3, 2025

Opens in a new windowSkipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock
Beach Getaway Just Refreshed, Sleeps 8 <4 br> EV level 2 charging- views

Beach Getaway Just Refreshed, Sleeps 8 <4 br> EV level 2 charging- views

Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
We really enjoyed our stay. I was a bit off put when we arrived and the yard and under the carport area were very messy. First impression was not a good one. The outside of the house and lawn need maintenance. The inside of the house was fine. The beds were comfortable, clean, and there were plenty ...

Reviewed on Nov 5, 2025

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Opens in a new windowBeach Getaway Just Refreshed, Sleeps 8 <4 br> EV level 2 charging- views
BEACHFRONT! Million Dollar Views! Panoramic views of the Gulf! Fall Discounts!

BEACHFRONT! Million Dollar Views! Panoramic views of the Gulf! Fall Discounts!

Alligator Point FL
This vacation home features laundry facilities.
Absolutely perfect! Amazing views! Our favorite vacation spot for sure. We usually stay on the other end of Alligator Point, we needed more space this year. I will say, if you are taking older folks, it is a lot of stairs. Other then that, perfect!

Reviewed on Oct 9, 2025

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Opens in a new windowBEACHFRONT! Million Dollar Views! Panoramic views of the Gulf! Fall Discounts!
The Panacea Motel

The Panacea Motel

2 out of 5
1545 Coastal Hwy Panacea FL
$117 nightly
The price is $131 total per night from Dec 29 to Dec 30
$131 total
Dec 29 - Dec 30
Total with taxes and fees
Stay at this motel in Panacea. Enjoy free WiFi, free parking, and hiking/biking on site. Popular attractions Panacea Springs and Woolley Park are located ...
Yes

Reviewed on Nov 19, 2025

Opens in a new windowThe Panacea Motel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Panacea?
Family vacations are where the best memories are made, but it's no secret that traveling with youngsters can be difficult. These kid-friendly Panacea hotels come with perks designed to keep young and old alike comfortable and happy: Put your bags down at Tide Creek Lookout. It comes with a nearby beach, animal viewing activities and a talent for making families feel welcome. Also check out Gated Water View Pool Home on Dickerson Bay. It offers a swimming pool, a travel crib and plenty of opportunities for family time.
Where can I find cheap hotels in Panacea?
At Travelocity you'll find really nice hotels in Panacea at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Panacea rather than in Panacea. We may find you even better rates, too.
How do I find the best Panacea hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Panacea then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Panacea?
The cheapest hotel in Panacea is $131. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Panacea?
There are 502 hotels in Panacea on Travelocity.
What are the best hotels in Panacea?
Panacea has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Panacea for you!
When is the best time to visit Panacea?
If you want the joy of a fun-filled trip in peak season, visit Panacea during February, April and September. If you'd prefer the peace of off-season, book a stay during quieter months, such as July, October and November.
When is the cheapest time to stay in Panacea?
Based on historic data is usually the cheapest month to visit Panacea. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Panacea?
There are multiple hotels in Panacea that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Panacea. We have plenty of kid-friendly hotels in Panacea to choose from on Travelocity!
Why book a hotel in Panacea through Travelocity?
Because we have the top hotels in Panacea! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Panacea on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Panacea hotel reviews by fellow wanderers

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

5 out of 5
Posted 6 days ago
Travelocity Verified Review
"The sunrise from this porch is breath taking. The house is well equipped and the the porch is simply amazing. Host was quick to respond and we will be renting this home again! "
A verified traveler stayed at 5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch
5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

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