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Top Panacea hotels

 Secluded Florida Beach Bungalow-best of both worlds-BEACH TIME & FISHING TIME!!

Secluded Florida Beach Bungalow-best of both worlds-BEACH TIME & FISHING TIME!!

Panacea FL
$364 nightly
The price is $397 total per night from Apr 26 to Apr 27
$397 total
Apr 26 - Apr 27
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
Loved the cottage. Only drawback is the seclusion. I’m sure in the busy season things are livelier. But we were looking for quiet and that’s what we got!

Reviewed on Mar 24, 2026

Opens in a new window Secluded Florida Beach Bungalow-best of both worlds-BEACH TIME & FISHING TIME!!
Beautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis

Beautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis

Alligator Point FL
This vacation home features an outdoor pool and a hot tub. Laundry facilities and barbecue grills are also provided.
This place was perfect!!!! Host was amazing, super clean and so so so cute!! We can't wait to come back and stay again!

Reviewed on Mar 25, 2026

Opens in a new windowBeautiful Waterfront, Pool, Private Hot Tub, Golf Cart, Kayaks, Bikes & Tennis
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

Alligator Point FL
$2,028 nightly
The price is $2,214 total per night from Apr 4 to Apr 5
$2,214 total
Apr 4 - Apr 5
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
Beautiful house with awesome views of the gulf and the bay from all rooms. Fenced in yard was perfect for our dog. Location is very relaxing. I can't wait to go back.

Reviewed on Mar 16, 2026

Opens in a new window7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs.

Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
We LOVED our stay at the Tiki House. The location is on our favorite part of Alligator Point (Mud Cove). Our son loves to cast the net for the Mullet and Shrimp that come into the Mud Cove area during this time of year. Loved the large kitchen bar that was perfect for our traditional Thanksgiving ...

Reviewed on Dec 2, 2025

Opens in a new windowTiki House is a Unique Beach Front gathering spot for family, friends and PUPs.
5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

Panacea FL
This vacation home features a garden, laundry facilities, and barbecue grills.
The sunrise from this porch is breath taking. The house is well equipped and the the porch is simply amazing. Host was quick to respond and we will be renting this home again!

Reviewed on Dec 19, 2025

Opens in a new window5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch
Best deal at Alligator Point

Best deal at Alligator Point

Alligator Point FL
This vacation home includes a garden and laundry facilities.
A clean and well equipped home. Great waterfront view. We were greeted by lady host, we were told owner was right next door, feel free to stop by with questions, or issues. When Wifi didn't connect, I walked over to get suggestions on getting a connection, and was chewed out for disturbing ...

Reviewed on Mar 15, 2026

Opens in a new windowBest deal at Alligator Point
The Panacea Motel

The Panacea Motel

2 out of 5
1545 Coastal Hwy Panacea FL
$109 nightly
The price is $122 total per night from Apr 5 to Apr 6
$122 total
Apr 5 - Apr 6
Total with taxes and fees
Stay at this motel in Panacea. Enjoy free WiFi, free parking, and hiking/biking on site. Popular attractions Panacea Springs and Woolley Park are located ...
Parking was easy, right outside the room. The room was tiny but wonderful and really nice for what it was. AC kept the room comfortable and is extremely quiet. Great communication from the staff about the only issue with the tv but beyond their control. Definitely will book again when we go back ...

Reviewed on Mar 22, 2026

Opens in a new windowThe Panacea Motel
Coastal Getaway on canal-steps to the beach

Coastal Getaway on canal-steps to the beach

Panacea FL
This vacation home features a garden, laundry facilities, and barbecue grills.
Opens in a new windowCoastal Getaway on canal-steps to the beach
Hideaway Beach Cottage on waterfront with amazing views.

Hideaway Beach Cottage on waterfront with amazing views.

Panacea FL
This cottage features a garden, laundry facilities, and barbecue grills.
Opens in a new windowHideaway Beach Cottage on waterfront with amazing views.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Panacea?
Family vacations are where the best memories are made, but it's no secret that traveling with youngsters can be difficult. These kid-friendly Panacea hotels come with perks designed to keep young and old alike comfortable and happy: Put your bags down at Tide Creek Lookout. It comes with a nearby beach, animal viewing activities and a talent for making families feel welcome. Also check out Gated Water View Pool Home on Dickerson Bay. It offers a swimming pool, a travel crib and plenty of opportunities for family time.
Where can I find cheap hotels in Panacea?
At Travelocity you'll find really nice hotels in Panacea at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Panacea rather than in Panacea. We may find you even better rates, too.
How do I find the best Panacea hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Panacea then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Panacea?
The cheapest hotel in Panacea is $122. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Panacea?
There are 546 hotels in Panacea on Travelocity.
What are the best hotels in Panacea?
Panacea has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Panacea for you!
When is the best time to visit Panacea?
If you want the joy of a fun-filled trip in peak season, visit Panacea during February, April and September. If you'd prefer the peace of off-season, book a stay during quieter months, such as July, October and November.
When is the cheapest time to stay in Panacea?
Based on historic data is usually the cheapest month to visit Panacea. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Panacea?
There are multiple hotels in Panacea that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Panacea. We have plenty of kid-friendly hotels in Panacea to choose from on Travelocity!
Why book a hotel in Panacea through Travelocity?
Because we have the top hotels in Panacea! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Panacea on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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