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Top Panacea hotels

Your Fall Escape: FSU Football & Scalloping

Your Fall Escape: FSU Football & Scalloping

Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
"We enjoyed our stay here so much and we were very sad to go! The place was AMAZING! It is family friendly and pet friendly. The beach and ocean are right where you can see them and easy to access. Utilize the outdoor shower to helo with sand tracking in and out. The laundry room is located down stairs ..."

Reviewed on Aug 1, 2026

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Opens in a new windowYour Fall Escape: FSU Football & Scalloping
5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch

Panacea FL
This vacation home features a garden, laundry facilities, and barbecue grills.
"Everyone had great time, house was very nice and accommodating for the whole family. Beds were very comfortable. Would definitely recommend mosquito spray though. Screened porch was a big plus for sitting outside at night. Overall a very peaceful place."

Reviewed on Aug 2, 2026

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Opens in a new window5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front

Alligator Point FL
$1,942 nightly
The price is $2,121 total per night from Sep 25 to Sep 26
$2,121 total
Sep 25 - Sep 26
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
"We had an amazing week. Best equipped home we have ever stayed. The privacy and peacefulness was just want we needed. Host was very responsive."

Reviewed on Aug 15, 2026

Opens in a new window7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Great sunrise view from dining area and decks. Easy beach access.

Great sunrise view from dining area and decks. Easy beach access.

Panacea FL
This vacation home featured laundry facilities and barbecue grills.
"When we arrived there was construction happening in front of the property (building a house directly in front of this one). Unfortunately it was blocking the unobstructed ocean view that was advertised. The construction was going to take place during the entire time of our stay. I contacted the host ..."

Reviewed on Sep 20, 2026

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Opens in a new windowGreat sunrise view from dining area and decks. Easy beach access.
Hideaway Beach Cottage on waterfront with amazing views.

Hideaway Beach Cottage on waterfront with amazing views.

Panacea FL
This cottage features a garden, laundry facilities, and barbecue grills.
"Booking this stay was incredibly easy. Hosts are responsive and very accommodating. Price was great, especially considering that we thought the property was even better in person. Pictures truly don’t do it justice. The small town of Panacea is a breath of fresh air. Not your typical touristy beach ..."

Reviewed on Sep 23, 2026

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Opens in a new windowHideaway Beach Cottage on waterfront with amazing views.
Coastal Getaway on canal-steps to the beach

Coastal Getaway on canal-steps to the beach

Panacea FL
This vacation home features a garden, laundry facilities, and barbecue grills.
"Awesome weekend staying at this location. We was within walking distance to the beach and fishing. Loved that it had a complete bathroom downstairs when we came in from fishing all day and night. Great communication with the host. Very prompt responding to questions. Will recommend to family and ..."

Reviewed on Sep 13, 2026

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Opens in a new windowCoastal Getaway on canal-steps to the beach
Lighthouse- enjoy the water, bask in the view

Lighthouse- enjoy the water, bask in the view

Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
"Every was great.. Most definitely would rent again."

Reviewed on Sep 19, 2026

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Opens in a new windowLighthouse- enjoy the water, bask in the view
BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.

Panacea FL
$571 nightly
The price is $624 total per night from Oct 20 to Oct 21
$624 total
Oct 20 - Oct 21
Total with taxes and fees
An outdoor pool is featured at this vacation home, along with a garden and laundry facilities.
"Charming beach house just steps away from the beach. The beach was quiet which is a great alternative to crowded beaches. Robin was very responsive and helpful. Would love to come back!"

Reviewed on Aug 1, 2026

Opens in a new windowBEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.
The Panacea Motel

The Panacea Motel

2 out of 5
1545 Coastal Hwy Panacea FL
$109 nightly
The price is $121 total per night from Oct 25 to Oct 26
$121 total
Oct 25 - Oct 26
Total with taxes and fees
Stay at this motel in Panacea. Enjoy free WiFi, free parking, and hiking/biking on site. Popular attractions Panacea Springs and Woolley Park are located ...
"Other than everything close perfect spot"

Reviewed on Sep 18, 2026

Opens in a new windowThe Panacea Motel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Panacea?
Family vacations are where the best memories are made, but it's no secret that traveling with youngsters can be difficult. These kid-friendly Panacea hotels come with perks designed to keep young and old alike comfortable and happy: Put your bags down at Tide Creek Lookout. It comes with a nearby beach, animal viewing activities and a talent for making families feel welcome. Also check out Gated Water View Pool Home on Dickerson Bay. It offers a swimming pool, a travel crib and plenty of opportunities for family time.
Where can I find cheap hotels in Panacea?
At Travelocity you'll find really nice hotels in Panacea at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Panacea rather than in Panacea. We may find you even better rates, too.
How do I find the best Panacea hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Panacea then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Panacea?
The cheapest hotel in Panacea is $121. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Panacea?
There are 556 hotels in Panacea on Travelocity.
What are the best hotels in Panacea?
Panacea has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Panacea for you!
When is the best time to visit Panacea?
If you want the joy of a fun-filled trip in peak season, visit Panacea during February, April and September. If you'd prefer the peace of off-season, book a stay during quieter months, such as July, October and November.
When is the cheapest time to stay in Panacea?
Based on historic data is usually the cheapest month to visit Panacea. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Panacea?
There are multiple hotels in Panacea that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Panacea. We have plenty of kid-friendly hotels in Panacea to choose from on Travelocity!
Why book a hotel in Panacea through Travelocity?
Because we have the top hotels in Panacea! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Panacea on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Panacea hotel reviews by fellow wanderers

Hideaway Beach Cottage on waterfront with amazing views.

Hideaway Beach Cottage on waterfront with amazing views.

5 out of 5
Posted 6 hours ago
Travelocity Verified Review
"Booking this stay was incredibly easy. Hosts are responsive and very accommodating. Price was great, especially considering that we thought the property was even better in person. Pictures truly don’t do it justice. The small town of Panacea is a breath of fresh air. Not your typical touristy beach town. We wanted to have a slow, low stim vacation with our young kids and that’s exactly what we got. There are still enough restaurants to choose from if you want to eat out every night in the town and even more within a 20 minute drive. If you want to stay in and cook, the kitchen has plenty of room and is stocked well. Large dining table with more than enough room. The living area large and comfy. We didn’t use the second bedroom beds because our kids are still in pack and plays. Two fit in the room just fine. The master bedroom mattress was genuinely one of the most comfortable beds I’ve slept in. Screened in porch was amazing to relax in and let in 0 bugs somehow. So impressed. Our absolute favorite part though was the yard and little beach on the bay. Our kids can’t stand to be inside and they played for HOURS in the good sized yard. We watched stingrays, fish, and birds in the bay. The only thing I’d tell people to consider is that the beach can be a drive. The closest beach, Mashes Sands, had almost no shoreline so you’ll need to drive \- 20 minutes for a beach. This didn’t bother us at all. There is virtually no traffic and tons of options."
A verified traveler stayed at Hideaway Beach Cottage on waterfront with amazing views.
Hideaway Beach Cottage on waterfront with amazing views.

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