Book Hotels in Panacea, FL
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Panacea hotels

Your Private Slice of the Forgotten Coast—Steps to Sand
Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
"We enjoyed our stay here so much and we were very sad to go! The place was AMAZING! It is family friendly and pet friendly. The beach and ocean are right where you can see them and easy to access. Utilize the outdoor shower to helo with sand tracking in and out. The laundry room is located down stairs ..."
Reviewed on Aug 1, 2026

Hideaway Beach Cottage on waterfront with amazing views.
Panacea FL
This cottage features a garden, laundry facilities, and barbecue grills.
"Great hidden gem, perfect for families wanting to vacation with their dog."
Reviewed on Aug 3, 2026

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front
Alligator Point FL
$1,980 nightly
The price is $2,169 total per night from Aug 16 to Aug 17
$2,169 total
Aug 16 - Aug 17
Total with taxes and fees
This vacation home features a garden, laundry facilities, and barbecue grills.
"The house was perfect for our family, especially my mom who has trouble walking. The elevator worked perfectly, the boardwalk was short and close to the ocean. She and my dad loved sitting on the deck and watching us all on the beach. Communication was great, including updates on the tropical storm. ..."
Reviewed on Jul 25, 2026

Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations
Alligator Point FL
This vacation home featured laundry facilities and barbecue grills.
"We’ve spent many years on Alligator Point, and this has to be our new favorite house to stay in. The guys fished from under the house most of the time. It was a wonderful trip!!"
Reviewed on Aug 8, 2026

5 Bedroom Beach House Slps 12 - Private Beach - Shells - Fishing -Screened porch
Panacea FL
This vacation home features a garden, laundry facilities, and barbecue grills.
"Everyone had great time, house was very nice and accommodating for the whole family. Beds were very comfortable. Would definitely recommend mosquito spray though. Screened porch was a big plus for sitting outside at night. Overall a very peaceful place."
Reviewed on Aug 2, 2026

NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!
Panacea FL
A hot tub is featured at this vacation home, along with laundry facilities and barbecue grills.
"Fantastic views of the water! Right on the beach! The house was immaculately done! The rooms were big especially the master bedroom! Kitchen had everything and more than needed! Can’t say enough of how much fun we had at this very well put together luxury accommodation!!! Beds were exceptional! Would ..."
Reviewed on Jul 18, 2026

40% off for monthly rate, Views of the gulf & bay, 4 porches w/panoramic views.
Alligator Point FL
This vacation home includes a garden and laundry facilities.
"Nice views"
Reviewed on Jul 31, 2026

The Panacea Motel
1545 Coastal Hwy Panacea FL
$119 nightly
The price is $133 total per night from Aug 13 to Aug 14
$133 total
Aug 13 - Aug 14
Total with taxes and fees
Stay at this motel in Panacea. Enjoy free WiFi, free parking, and hiking/biking on site. Popular attractions Panacea Springs and Woolley Park are located ...

Coastal Getaway on canal-steps to the beach
Panacea FL
This vacation home features a garden, laundry facilities, and barbecue grills.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Panacea hotel reviews by fellow wanderers

Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"We’ve spent many years on Alligator Point, and this has to be our new favorite house to stay in. The guys fished from under the house most of the time. It was a wonderful trip!!"
A verified traveler stayed at Gulf Breeze – Pet-Friendly 3BR Beachfront Stay with Stunning Views & Renovations
Explore More Ways to Travel with Travelocity
- Cottages in Crawfordville
- Condos in Crawfordville
- Hotels in St Marks
- Hotels in St George Island
- Buccaneer Inn
- Beach in St George Island
- Hotels in Sopchoppy
- Cabins in Sopchoppy
- Motels in Saint Teresa
- Hotels in Saint Teresa
- Cottages in Saint Teresa
- Hotels in Wakulla Beach
- Hotels near Tallahassee Memorial Medical Center
- Hotels near Tallahassee FL
- Hotels in Tallahassee
- Cabins in Wakulla County
- Hotels in Wakulla Springs
- Hotels near Wakulla Springs State Park
- Hotels in Woodville
- The Lodge At Wakulla Springs
- Pet Friendly in Tallahassee
- Motel 6 Tallahassee Fl - Downtown
- Luxury in Tallahassee
- Loyalty Inn Tallahassee
- Cabins in Panacea
- Condos in Panacea
- Aparthotels in Panacea
- Guesthouses in Panacea
- AWESOME VIEW On Private Gulf of Mexico Beach Majestic Views
- CONDO Water front bay breeze fishing paradise and family friendly 2 bedroom
- Bayfront Condo with Boat Slip
- Hotels in Crawfordville
- Pet Friendly in Crawfordville
- Golf in Crawfordville
- Beach in Crawfordville
- Aparthotels in Crawfordville
- Hotels near St Marks Lighthouse
- Hotels near St Marks National Wildlife Refuge
- Aparthotels in Tallahassee
- Bayside Retreat Panacea FL Bay Front Dock 2 Large Porches No Pets Wifi
- Beach in Panacea
- Beachfront Alligator Point Vacation Rental
- Turtles Nest BACK TO SCHOOL SPECIAL FOR AUGUST 23 2026-AUGUST 29 2026
- Best deal at Alligator Point
- Alligator Point Old Florida Beachfront Cottage
- Enchanted Cottage Beachfront Charming Retreat by the Sea
- Historical in Panacea
- Legasea Old Florida Beachfront Charm with Two Screen Porches Sleeps 7
- Ocean View in Panacea
- Pet Friendly in Panacea
- SALT AIR AND SERENDIPITY Unit B
- Hotels near Cascades Park
- Hotels in Carrabelle
- Franklin Inn
- Hotels near Bobby Bowden Field at Doak Campbell Stadium
- Hotels near Bald Point State Park
- Hotels near Apalachicola National Forest
- Hotels in Apalachicola
- Privatevacationhomes in Alligator Point
- Motels in Alligator Point
- Hotels in Alligator Point
- Condos in Alligator Point
- Apartments in Crawfordville
- Cabins in Crawfordville
- Sardegna- pool dock home by Mashes Sands Beach
- Shifting Sands Private Beach Front 3 Bd 2 Bath sleeps 8
- The Panacea Motel
- Pelican Perch
- Secluded Florida Beach Bungalow AUGUST SPECIAL-BOOK ANYTIME 8 7-8 19 20 OFF
- Motels in Panacea
- Privatevacationhomes in Panacea
- Hotels in Quincy
- Condos in Saint Teresa
- Budget in Tallahassee
- Kitchenette in Tallahassee
- Hotels near Ochlockonee River State Park
- Hotels in Ochlockonee Bay
- Hotels near Florida State University
- Hotels near Florida State Capitol Building
- Hotels near Florida A&M University
- Hotels near Donald L Tucker Civic Center
- Privatevacationhomes in Dog Island
- Beach in Wakulla County
- Motels in Crawfordville
- Flights to Saint Teresa
- Flights to Panacea
- Flights to Tallahassee
- Flights from Tampa (TPA) to Tallahassee (TLH)
- Flights from West Palm Beach (PBI) to Tallahassee (TLH)
- Flights from Miami (MIA) to Tallahassee (TLH)
- Flights from Orlando (MCO) to Tallahassee (TLH)
- Flights from Fort Lauderdale (FLL) to Tallahassee (TLH)
- Flights from Tallahassee FL






