Book Hotels in Saint Charles, IA
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Top Saint Charles hotels

Des Lux Hotel
800 Locust St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $189 total per night from Oct 26 to Oct 27
$189 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Enjoy ...
"Decided to do something different besides stay one of the big chain hotels. Hotel was very clean, staff was very nice, hotel had a very cozy feel. Room was pleasantly large and very comfortable. Was there for work but stopped at their bar when I got back because it looks so inviting."
Reviewed on Oct 16, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St, Des Moines, IA
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $155 total per night from Nov 2 to Nov 3
$155 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. WiFi in public areas is free. Valet parking, a business center, and a coffee shop are also ...
"One of my favorite places to stay. The room is clean and comfy always. Wonderful atmosphere."
Reviewed on Oct 14, 2025

Home2 Suites by Hilton Des Moines at Drake University
2650 University Ave., Des Moines, IA
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $118 total per night from Oct 26 to Oct 27
$118 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
"The property was clean and the staff was friendly and helpful. The shower gel and conditioner were empty."
Reviewed on Oct 18, 2025

Holiday Inn Express & Suites Des Moines Downtown by IHG
333 SW 11th St, Des Moines, IA
Fully refundable
$108 nightly
The price is $121 total per night from Oct 27 to Oct 28
$121 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Staff was very helpful when we checked in and helped us with the shuttle to our party"
Reviewed on Oct 18, 2025

Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr, West Des Moines, IA
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $103 total per night from Oct 26 to Oct 27
$103 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"Very comfortable bed, breakfast boil in bag food, not awful. Easy to get back on I 80."
Reviewed on Oct 20, 2025

Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave, Des Moines, IA
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $83 total per night from Oct 23 to Oct 24
$83 total
Oct 23 - Oct 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Would have like some different meat for breakfast, like bacon, or sausage. Not just biscuits and sausage."
Reviewed on Oct 18, 2025

Holiday Inn Downtown - Mercy Area by IHG
1050 6th Ave, Des Moines, IA
Fully refundable
$116 nightly
The price is $130 total per night from Oct 28 to Oct 29
$130 total
Oct 28 - Oct 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the gym and perks like free WiFi and a free airport shuttle. A 24-hour business center, ...
"Average room. Great location"
Reviewed on Oct 15, 2025

AmericInn by Wyndham Des Moines Airport
1920 Hackley Ave, Des Moines, IA
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $78 total per night from Oct 26 to Oct 27
$78 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free full breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage ...
"Good price! We'd stay again."
Reviewed on Oct 12, 2025

Motel 6 West Des Moines, IA
7655 Office Plaza Dr N, West Des Moines, IA
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $56 total per night from Nov 5 to Nov 6
$56 total
Nov 5 - Nov 6
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A terrace, a snack bar/deli, and laundry facilities are also on ...
"The room each huge but it was clean and I got a good sleep there. Worth it for the price."
Reviewed on Oct 12, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Saint Charles hotel reviews by fellow wanderers

Fairfield Inn and Suites by Marriott Des Moines West
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Very comfortable bed, breakfast boil in bag food, not awful. Easy to get back on I 80."
A verified traveler stayed at Fairfield Inn and Suites by Marriott Des Moines West
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