City center stay.With a stay at this well-placed vacation home, you'll be half a mile (1 km) from Ohio River Valley and within 3 miles (5 km) of KFC Yum Center. Falls of the Ohio Interpretive State Park and Ohio River are also within half a mile (1 km).
~ Deaconess Guesthouse — Historic Elegance on the Ohio River, Minutes from Louisville & Jeffersonville ~
★ Where History Meets Modern Luxury: Step into timeless sophistication at Deaconess Guesthouse, a masterfully reimagined 1800s landmark that once served as Jeffersonville’s first public hospital. Painstakingly restored by Charming Vacation Homes, this distinguished estate blends rich history with refined, boutique-style living. Overlooking the serene Ohio River and just minutes from downtown Louisville, the Bourbon Trail, and Jeffersonville’s lively riverfront district, it offers an experience that is both captivating and unforgettable.
★ Designed for Connection & Celebration: With 8 beautifully appointed bedrooms and 6 spa-inspired bathrooms across four private suites, the estate accommodates up to 24 guests in absolute comfort. Perfect for family reunions, executive retreats, weddings, and milestone celebrations, the home’s thoughtful layout provides an ideal balance of gathering spaces and peaceful privacy. Every corner—from the grand living areas to the artfully curated décor—has been designed to inspire conversation, laughter, and lasting memories.
★ Signature Amenities & Exclusive Touches: 1. Private Hot Tub & Fire Pit – Relax under the stars in your own riverfront sanctuary 2. Wraparound Porches & Scenic Balconies – Begin your day with sunrise coffee, end with sunset cocktails 3. Stargazing Dome Experience – A whimsical retreat for dreamers of all ages 4. Ample On-Site Parking – Effortless access for large groups, luxury vehicles, and VIP transport
★ The Perfect Location: - Walk to Downtown Jeffersonville – Boutique shopping, acclaimed dining, and vibrant riverfront entertainment - 2.5 Miles to Downtown Louisville – Discover bourbon distilleries, Churchill Downs, world-class museums, and live music - Adventure Awaits – Kayaking, biking trails, waterfront festivals, and outdoor concerts just steps away
★ Your Private Riverfront Retreat: From tranquil mornings on the porch to fireside evenings beneath the stars, Deaconess Guesthouse invites you to slow down, reconnect, and indulge in life’s finer moments. Its historic legacy, stunning river views, and luxury amenities create an experience that transcends the ordinary—a stay where every detail tells a story.
Reserve your stay today and experience Jeffersonville’s most iconic riverfront estate—where history, luxury, and unforgettable memories meet.
★ CONVENIENT LOCATION The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins) - Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins) - Churchill Downs (DERBY) - 7.7 miles (15 mins) - KFC Yum Center - 2.3 miles (7 mins) - Waterfront Park - 3.4 miles (9 mins) - Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins) - University of Louisville - 6.5 miles (12 mins) - Kentucky Fairgrounds - 6.5 miles (10 min) - Kentucky Exposition Center - 6.7 miles (11 mins) - Kentucky Kingdom - 7.4 miles (13 mins) - Louisville Airport - 8.6 miles (10 mins) - Highland Festival Grounds - 8.5 miles (12 mins) - Louisville Mega Cavern - 10.2 miles (19 mins) - Ford LAP Plant - 10.9 miles (16 mins) - UPS Worldport - 11.2 miles (20 mins) - Waverly Hills Sanatorium - 17 miles (30 mins) - Valhalla Golf Club - 19 miles (27 mins)
PROPERTY HIGHLIGHTS ★ Exclusive Riverfront Retreat near Downtown Louisville/Jeffersonville: Experience an extraordinary blend of historic elegance and modern sophistication at this rare architectural masterpiece—ideally located just minutes from Louisville, Jeffersonville, New Albany and Clarksville. ★ Prime Ohio Riverfront Setting: Wake up to breathtaking panoramic views of the Ohio River and stroll to Jeffersonville’s vibrant downtown, filled with boutique shopping, fine dining, live entertainment and local festivals. ★ Historic Charm Meets Modern Luxury: This meticulously restored landmark showcases timeless craftsmanship, curated interiors and designer finishes—creating an atmosphere that’s both refined and deeply inviting. ★ Scenic Views & Inviting Spaces: Enjoy your morning coffee or evening wine on covered porches and private balconies overlooking the river’s shimmering waters—perfect for unwinding and taking in the view. ★ Designed for Comfort & Connection: With 8 elegant bedrooms and 6 spa-inspired bathrooms, this home is designed for both relaxation and togetherness, offering open, light-filled spaces ideal for family and friends. ★ Chef-Inspired Living: Featuring four gourmet kitchens with premium appliances and upscale touches, this home provides the perfect canvas for culinary experiences and memorable gatherings. ★ Family & Pet Friendly: From cozy reading nooks to kid-friendly zones and pet accommodations, every detail is thoughtfully designed so everyone—two-legged or four—feels perfectly at home. ★ Private Outdoor Oasis: Unwind in the hot tub, gather by the fire pit, relax under the Hyperdome or gazebo and enjoy outdoor dining and lawn games under the starlit sky. ★ Entertainment for Every Occasion: Stay entertained with Smart Roku TVs in every bedroom, indoor and outdoor games and multiple lounge spaces that make every stay as fun as it is relaxing. ★ Perfect for Groups & Celebrations: Ideal for family reunions, retreats, and extended stays, the property offers 4 washer/dryer sets, parking for 8 and flexible gathering spaces designed to bring people together. ★ Your Riverfront Escape Awaits: Discover the ultimate fusion of history, luxury, and location—a one-of-a-kind getaway where every moment feels like a celebration on the banks of the Ohio River.
★ TOP 2025 UPCOMING EVENTS -Jack O’ Lantern Spectacular: Oct 2025 -Halloween Weekends Louisville South KOA Holiday: Oct 2025
★ OTHER 2025 UPCOMING EVENTS (Including TRADE SHOWS) -Equipment Expo: Oct 21th to 24th, 2025 -North American International Livestock Exposition: Nov 6th to 20th, 2025
NOTE: 1) Must be 25 or older to book. 2) Please review house rules before booking. Rental Agreement & Security Hold: Guests must e-sign our rental agreement and Must submit a $500 off-platform security hold that will be collected upon signing rental agreement but it will not be placed until 2 days prior to arrival and released 7 days after departure, if no damages are reported. Please note we are API Connected to a hotel-style software called OwnerRez to safely and securely take off-platform security deposits. 3) ** STRICT CANCELLATION for DERBY/ Bourbon & Beyond ** 4) Visitors are not permitted unless you make a special request to the host and receive approval. 5) We have exterior surveillance with voice and recording capabilities of the parking area and front door. They are in place for security of guests and the home. We do NOT have interior cameras nor camera in the backyard. 6) The Dome is not recommended for use during hot summer months. We suggest enjoying the other amenities during warmer months for optimal comfort. 7) We cannot accommodate early check-ins or late check-outs for same-day turnarounds. 8) For days without same-day turnarounds, we offer early check-ins and late check-outs at the following rates: $100 for up to 2 hours, $250 for 2 to 4 hours, and a full day's rate for more than 4 hours. 9) Please note that for cancellations of bookings made on platforms other than Airbnb, a Stripe card processing fee of 3% will be deducted from the total refund.
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANK YOU!
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If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Area rugs in public areas
Handrails in hallways
Handrails in stairways
Hardwood flooring in public areas
Smooth flooring in public areas
Thin carpet in public areas
Tile flooring in public areas
Well-lit path to entrance
Smoking not allowed
Services and conveniences
Iron/ironing board
Location highlights
In the city center
Near a hospital
Near a zoo
Near the marina
On a river
On the waterfront
Things to do
Arcade/game room
Water park
Casino nearby
Fishing nearby
Golfing nearby
Kayaking nearby
Motor boating nearby
Theme park nearby
Winery tours nearby
Safety features
Carbon monoxide detector (host has indicated there is a carbon monoxide detector on the property)
Smoke detector (host has indicated there is a smoke detector on the property)
First aid kit
Fire extinguisher
Deadbolt lock
General
At least 80% lighting from LEDs
Garden
Recycling
Unit size: 5,800 square feet
Water-efficient showers
Water-efficient toilets
Policies
Check-in
Check-in time starts at 4:00 PM
Contactless check-in available
Minimum check-in age: 25
Check-out
Check-out before 10:00 AM
Special check-in instructions
You will receive an email from the host with check-in and check-out instructions
Rules
Must sign rental agreement upon booking which will be sent via email
A $500 security hold will be placed 2 days prior to arrival and released 7 days after departure, if no damages are reported
Must follow all house rules listed in the end of the description and also on the rental agreement.
Pets
Pets are welcome
Service animals are exempt from fees
Note from host: Up to 2 pets 50lbs max.
Children and extra beds
Children are welcome.
Events
No events allowed
Smoking
Smoking is not permitted
Important information
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
Onsite parties or group events are strictly prohibited
Host has indicated there is a carbon monoxide detector on the property
Host has indicated there is a smoke detector on the property
Safety features at this property include a fire extinguisher, a first aid kit, and a deadbolt lock
This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. Onsite parties or group events are strictly prohibited. For guests' safety, the property includes a carbon monoxide detector, a fire extinguisher, a smoke detector, a first aid kit, and a deadbolt lock in each accommodation.
Property is also known as
orp5b65a95x
Frequently asked questions
How close is 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities to the airport?
This vacation home is 9.3 mi (16-min drive) away from the Louisville, KY (LOU-Bowman Field) airport, the closest popular airport to the property.
Does 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities have an airport shuttle?
Airport shuttle services are not available at this vacation home.
Does 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities offer free breakfast?
This vacation home does not offer free breakfast.
Is there a casino at 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities?
No, there is no casino at this vacation home, but Horseshoe Southern Indiana Casino (25-min drive) is nearby.
What time is check-in at 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities?
Check-in begins at 4:00 PM.
Is there free parking at 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities?
Free parking is not available at this vacation home.
Does 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities have a pool?
This vacation home does not have a pool.
Does 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities have a spa?
There are no spa services available at this vacation home.
How close is 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities to downtown Jeffersonville?
This vacation home is 0.9 mi away from Jeffersonville.
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.
10/10
Cleanliness
Rating 10 - Excellent. 14 out of 14 reviews
10 - Excellent
14
Rating 8 - Good. 0 out of 14 reviews
8 - Good
0
Rating 6 - Okay. 0 out of 14 reviews
6 - Okay
0
Rating 4 - Poor. 0 out of 14 reviews
4 - Poor
0
Rating 2 - Terrible. 0 out of 14 reviews
2 - Terrible
0
Reviews
10/10 Excellent
Kurtis Z.
Oct 6, 2025
Liked: Cleanliness
The home is terrific and the location is great in terms of views of the Ohio River and proximity to downtown Louisville.
Kurtis Z.
Stayed 3 nights in Oct 2025
10/10 Excellent
Stuart P.
Sep 29, 2025
Liked: Cleanliness
Amazing property with great location near downtown Louisville. Very seamless process all around. Highly recommend!
Stuart P.
Stayed 4 nights in Sep 2025
10/10 Excellent
Jonathon C.
Jul 19, 2025
Liked: Cleanliness
Large family vacation
We have a large (16 person) family that was looking to vacation in the Louisville area. We found this place that could accommodate everyone under one roof. The location was great as it was only minutes from downtown Louisville. The pictures and description of the property were as advertised. The only issue we ran into were the lack of venthoods in the kitchens made cooking a little smokey at times. We would have loved to use the back yard but we were unable to due to the time of year (heat and mosquitoes). Overall the property was as advertised and we would definitely recommend for larger parties like ours.
Jonathon C.
Stayed 4 nights in Jul 2025
10/10 Excellent
Kristen F.
Jul 11, 2025
Liked: Cleanliness
Wedding Getaway
We rented all four units of this home for a getaway with 19 people. We fit beyond perfectly in the rooms and the two sofa beds, which a friend of mine said she hasn’t slept that well in months. Having the four kitchens, extra bathrooms and fun outdoor area was the extra bonus. Location is great and there’s tons of parking. Kapil was easy to communicate with the entire weekend!
Kristen F.
Stayed 3 nights in Jul 2025
10/10 Excellent
Cindy C.
Jul 1, 2025
Liked: Cleanliness
Great family time
This property is essentially 4 separate apartments that are connected with a center hallway. It was a great set up for our family reunion.
Cindy C.
Stayed 3 nights in Jun 2025
10/10 Excellent
Corey T., Ottawa, Canada
Jun 27, 2025
Liked: Cleanliness
Nice space, place, hospitality
Great communications, nice spaces for a group, clean, and was a nice time.
Corey T.
Stayed 5 nights in Jun 2025
10/10 Excellent
katherine k.
Jun 15, 2025
Liked: Cleanliness
Awesome location for enjoying the barges on the river, walking to the Big Four walking bridge, and dinner in Jeffersonville! We spent most of our time on the riverside porch with a breeze! The Deaconess Guest House is well cared for and we felt welcomed by the clean, well appointed living spaces.
katherine k.
Stayed 3 nights in Jun 2025
10/10 Excellent
derald g.
Apr 15, 2025
Liked: Cleanliness
Care Free
From the time of Booking Kapil was great at communicating. He was very professional and polite through out our stay, checking in and allowing us to reach out at our convenance. The property was as advertised. A quite location on the river with local bars and restaurants within walking distance. Our group enjoyed the backyard in the evenings playing corn hole and sitting around the fire. The place was very clean inside and out and all things where in working order. I would highly recommend for large groups as there is plenty of space to hangout or take a few minutes away from the group when you need it. I have stayed in a ton of VRBOs and this one is in my top 10 for overall value, host performance, and cleanliness.
derald g.
Stayed 5 nights in Apr 2025
10/10 Excellent
Amanda C.
Apr 6, 2025
Liked: Cleanliness
Great location!
This house was perfect for our company. We were able to spread out and have our own rooms. The host was amazing! We unfortunately had scary weather while we were there and Kapil went above and beyond to make sure we were safe. Would definitely stay here again!
Amanda C.
Stayed 5 nights in Apr 2025
10/10 Excellent
Jeannine G.
Mar 17, 2025
Liked: Cleanliness
JG
The house was perfect for our group. It was clean and the decor was beautiful. Judy s short ride to all of our Louisville destinations. The host was very responsive. We look forward to staying at this property again!
Jeannine G.
Stayed 3 nights in Mar 2025
10/10 Excellent
Tammy W.
Dec 12, 2024
Liked: Cleanliness
Wonderful in every way!
Fantastic experience! The property was exactly as described and the booking experience smooth and easy. All of my questions were answers promptly. Check-in was a breeze with fantastic lighting outside when arriving after dark. The propertly is beautiful and our corporate group enjoyed the stay immensely. The property met every need we had from the private spaces, group gathering and meeting spaces and comfortable outdoor areas. The views along the river are gorgeous and sunrise over the river was spectacular. The kitchens met our needs when we cooked in and there are also great dining options nearby for eating out or carrying out. Will definately book here again!
Tammy W.
Stayed 3 nights in Dec 2024
10/10 Excellent
Troy W.
Dec 4, 2024
Liked: Cleanliness
Awesome, spacious, beautiful spot!!
Kapil was a great host. Went out of the way to make sure we had everything we needed for a perfect trip! Enjoyed the location, backyard, space and game room upstairs. Thanks for everything, would definitely stay here again!
Troy W.
Stayed 4 nights in Nov 2024
10/10 Excellent
Brian M., Columbia, IL
Sep 12, 2024
Liked: Cleanliness
Company Management Retreat
Property is fantastic. Very nicely appointed and equipped. The view of the Ohio River is fantastic and the backyard is set up for entertaining and fun! Great property and great owner communication.
Brian M.
Stayed 2 nights in Sep 2024
10/10 Excellent
Mike P.
Aug 12, 2024
Liked: Cleanliness
Great spot for Louisville!
We had a great time- the property was perfect for our group of 14. Would stay here again!