Explore 10 Luxury Hotels in Little Italy

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Best Luxury Hotels in Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

1646 Front St San Diego CA
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $176 total per night from Nov 19 to Nov 20
$176 total
Nov 19 - Nov 20
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
9/10 Wonderful! (1,127 reviews)
"Staff was excellent! Great location too."

Reviewed on Nov 3, 2026

Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown

San Diego CA
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $170 total per night from Nov 17 to Nov 18
$170 total
Nov 17 - Nov 18
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, and express check-in. ...
8.2/10 Very Good! (2,809 reviews)
"Room was clean and comfortable. Breakfast was great!"

Reviewed on Nov 3, 2026

Opens in a new windowHampton Inn San Diego-Downtown
Harborview Inn & Suites San Diego Harbor

Harborview Inn & Suites San Diego Harbor

550 West Grape St San Diego CA
$79 nightly
The price is $90 total per night from Nov 5 to Nov 6
$90 total
Nov 5 - Nov 6
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-in. Express ...
7.6/10 Good! (1,006 reviews)
"Staff is SUPER friendly"

Reviewed on Nov 3, 2026

Opens in a new windowHarborview Inn & Suites San Diego Harbor
Porto Vista Hotel Downtown

Porto Vista Hotel Downtown

1835 Columbia St San Diego CA
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $121 total per night from Dec 2 to Dec 3
$121 total
Dec 2 - Dec 3
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, conference space, ...
7.4/10 Good! (1,411 reviews)
"Staff was super friendly and our upgrade to a suite was perfect! This was our second stay here"

Reviewed on Nov 3, 2026

Opens in a new windowPorto Vista Hotel Downtown
Found Hotel San Diego

Found Hotel San Diego

505 West Grape Street San Diego CA
Free WiFi in public areas, a terrace, and a garden are available at this hotel. A picnic area and luggage storage are also provided.
6.8/10 (997 reviews)
"It was just ok"

Reviewed on Jun 5, 2023

Opens in a new windowFound Hotel San Diego
Urban Boutique Hotel

Urban Boutique Hotel

1654 Columbia Street San Diego CA
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $147 total per night from Dec 3 to Dec 4
$147 total
Dec 3 - Dec 4
Total with taxes and fees
Free WiFi in public areas, a picnic area, and luggage storage are available at this hotel. Enjoy the free continental breakfast each morning. There's a safe ...
Opens in a new windowUrban Boutique Hotel
Motel 6 San Diego Airport - Harbor

Motel 6 San Diego Airport - Harbor

2353 Pacific Highway San Diego CA
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $88 total per night from Nov 9 to Nov 10
$88 total
Nov 9 - Nov 10
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
Opens in a new windowMotel 6 San Diego Airport - Harbor
La Pensione Hotel

La Pensione Hotel

606 West Date Street San Diego CA
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...
Opens in a new windowLa Pensione Hotel
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More 4 star hotels in Little Italy

5 star hotels in Little Italy

Little Italy Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Little Italy luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Little Italy to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Little Italy will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Little Italy, and plan your next opulent escape.


Little Italy hotels essential information

Accommodation
8,622 hotels
Lowest Price
$88
Highest Price
$724
Popular hotels
Harborview Inn & Suites San Diego Harbor, Urban Boutique Hotel, Motel 6 San Diego Airport - Harbor, La Pensione Hotel, Found Hotel San Diego, Porto Vista Hotel Downtown, Hampton Inn San Diego-Downtown, Courtyard by Marriott San Diego Downtown Little Italy

Popular Luxury Stays in Little Italy

Recent Little Italy Hotel Reviews By Fellow Wanderers