Explore 10 Luxury Hotels in Little Italy

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Best Luxury Hotels in Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

1646 Front St San Diego CA
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $187 total per night from May 25 to May 26
$187 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
9/10 Wonderful! (582 reviews)
This property was great came in town for an outpatient surgery right across the border. My appointment wasn’t until two pm, I booked a king room however it wasn’t ready when I arrived at noon so they allowed me to check into a double queen early. When I got in the room the woman from the front desk ...

Reviewed on May 9, 2026

Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
Urban Boutique Hotel

Urban Boutique Hotel

1654 Columbia Street San Diego CA
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $147 total per night from May 10 to May 11
$147 total
May 10 - May 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
8.6/10 Excellent! (1,290 reviews)
It was perfect for us. Staff was friendly and got us discount on tickets for zoo. Bed was fine and breakfast was good and had some protein choices. Would stay again when in area, great location.

Reviewed on May 9, 2026

Opens in a new windowUrban Boutique Hotel
La Pensione Hotel

La Pensione Hotel

606 West Date Street San Diego CA
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $139 total per night from May 19 to May 20
$139 total
May 19 - May 20
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...
8.6/10 Excellent! (1,974 reviews)
The room was tiny with the basics and modern amenities. We were put in room 202 directly across from the elevator. The sink was outside the bathroom. The one ceiling light over the sink was dim yellow light and off-center so it was difficult to see yourself clearly when getting ready. The mirror ...

Reviewed on May 8, 2026

Opens in a new windowLa Pensione Hotel
Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown

San Diego CA
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $153 total per night from May 25 to May 26
$153 total
May 25 - May 26
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, and express check-in. ...
8.2/10 Very Good! (2,508 reviews)
Little older hotel but rooms were really clean. Walking distance to the harbour.

Reviewed on May 8, 2026

Opens in a new windowHampton Inn San Diego-Downtown
Harborview Inn & Suites San Diego Harbor

Harborview Inn & Suites San Diego Harbor

550 West Grape St San Diego CA
$83 nightly
The price is $94 total per night from May 10 to May 11
$94 total
May 10 - May 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-in. Express ...
7.2/10 Good! (1,005 reviews)
Parking great

Reviewed on May 5, 2026

Opens in a new windowHarborview Inn & Suites San Diego Harbor
Motel 6 San Diego Airport - Harbor

Motel 6 San Diego Airport - Harbor

2353 Pacific Highway San Diego CA
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $92 total per night from May 10 to May 11
$92 total
May 10 - May 11
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
7.2/10 Good! (1,013 reviews)
Very close to the airport and Little Italy

Reviewed on May 7, 2026

Opens in a new windowMotel 6 San Diego Airport - Harbor
Porto Vista Hotel Downtown

Porto Vista Hotel Downtown

1835 Columbia St San Diego CA
$114 nightly
The price is $132 total per night from May 10 to May 11
$132 total
May 10 - May 11
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...
7/10 Good! (1,278 reviews)
No desayumos ahi

Reviewed on May 8, 2026

Opens in a new windowPorto Vista Hotel Downtown
The Pacific

The Pacific

1655 Pacific Hwy San Diego CA
An outdoor pool, free self parking, and concierge services are featured at this hotel. A terrace, express check-out, and luggage storage are also on offer.
6/10 (396 reviews)
We never went to The Pacific!! We got a text from Expedia telling us the Pacific was closed due to renovations and we were booked at Motel 6 Chula Vista. We paid $50. to take us there only to find out we did not have a reservation. So Expedia has our $274. and we have no accommodations. We rebooked ...

Reviewed on Oct 8, 2022

Opens in a new windowThe Pacific
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More 4 star hotels in Little Italy

5 star hotels in Little Italy

Little Italy Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Little Italy luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Little Italy to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Little Italy will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Little Italy, and plan your next opulent escape.


Little Italy hotels essential information

Accommodation
8,452 hotels
Lowest Price
$92
Highest Price
$792
Popular hotels
Harborview Inn & Suites San Diego Harbor, Urban Boutique Hotel, Motel 6 San Diego Airport - Harbor, La Pensione Hotel, Porto Vista Hotel Downtown, Hampton Inn San Diego-Downtown, Courtyard by Marriott San Diego Downtown Little Italy, The Pacific

Popular Luxury Stays in Little Italy

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