Explore 10 Luxury Hotels in Little Italy

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Best Luxury Hotels in Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

1646 Front St San Diego CA
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $155 total per night from Apr 5 to Apr 6
$155 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet ...
9/10 Wonderful! (431 reviews)
Cute and local

Reviewed on Mar 15, 2026

Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
Urban Boutique Hotel

Urban Boutique Hotel

1654 Columbia Street San Diego CA
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $183 total per night from Apr 6 to Apr 7
$183 total
Apr 6 - Apr 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
8.6/10 Excellent! (1,271 reviews)
If you are looking for an affordable place to stay in little italy, this is right in the middle of everything. however the hotel is just a little run down and the walls were so thin that we couldn’t get any sleep due to our neighbors TV blasting. Also check-in was at 3 pm but our room wasn’t ready ...

Reviewed on Mar 10, 2026

Opens in a new windowUrban Boutique Hotel
La Pensione Hotel

La Pensione Hotel

606 West Date Street San Diego CA
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $169 total per night from Apr 1 to Apr 2
$169 total
Apr 1 - Apr 2
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...
8.6/10 Excellent! (1,918 reviews)
Room 1019, and bed very comfy and clean. TV makes weird LOUD noise when turning on and off. Maid didn't come day 2 despite taking off Do Not Disturb sign.

Reviewed on Mar 15, 2026

Opens in a new windowLa Pensione Hotel
Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown

San Diego CA
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $147 total per night from Apr 7 to Apr 8
$147 total
Apr 7 - Apr 8
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, and express check-in. ...
8/10 Very Good! (2,422 reviews)
Very bad hotel

Reviewed on Mar 15, 2026

Opens in a new windowHampton Inn San Diego-Downtown
Harborview Inn & Suites San Diego Harbor

Harborview Inn & Suites San Diego Harbor

550 West Grape St San Diego CA
$86 nightly
The price is $98 total per night from Mar 22 to Mar 23
$98 total
Mar 22 - Mar 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-in. Express ...
7.2/10 Good! (1,006 reviews)
Roaches in the room and it smelled

Reviewed on Mar 13, 2026

Opens in a new windowHarborview Inn & Suites San Diego Harbor
Motel 6 San Diego Airport - Harbor

Motel 6 San Diego Airport - Harbor

2353 Pacific Highway San Diego CA
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $104 total per night from Mar 22 to Mar 23
$104 total
Mar 22 - Mar 23
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. Staff at the 24-hour front desk can provide ...
7.2/10 Good! (1,002 reviews)
motel 6 was great

Reviewed on Mar 14, 2026

Opens in a new windowMotel 6 San Diego Airport - Harbor
Porto Vista Hotel Downtown

Porto Vista Hotel Downtown

1835 Columbia St San Diego CA
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $193 total per night from Mar 18 to Mar 19
$193 total
Mar 18 - Mar 19
Total with taxes and fees
A restaurant and a rooftop terrace are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
7/10 Good! (1,238 reviews)
The room was clean and the windows faced a side street. The bed was firm and comfortable. The hand soap and shampoo dispensers definitely needed to be replaced, so we did not use them at all. Housekeeping was only on request, and parking is Valet only and now costs $55/night for regular cars/ $65 ...

Reviewed on Mar 10, 2026

Opens in a new windowPorto Vista Hotel Downtown
The Pacific

The Pacific

1655 Pacific Hwy San Diego CA
An outdoor pool, free self parking, and concierge services are featured at this hotel. A terrace, express check-out, and luggage storage are also on offer.
6/10 (396 reviews)
We never went to The Pacific!! We got a text from Expedia telling us the Pacific was closed due to renovations and we were booked at Motel 6 Chula Vista. We paid $50. to take us there only to find out we did not have a reservation. So Expedia has our $274. and we have no accommodations. We rebooked ...

Reviewed on Oct 8, 2022

Opens in a new windowThe Pacific
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More 4 star hotels in Little Italy

5 star hotels in Little Italy

Little Italy Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Little Italy luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Little Italy to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Little Italy will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Little Italy, and plan your next opulent escape.


Little Italy hotels essential information

Accommodation
8,375 hotels
Lowest Price
$98
Highest Price
$793
Popular hotels
Harborview Inn & Suites San Diego Harbor, Urban Boutique Hotel, Motel 6 San Diego Airport - Harbor, La Pensione Hotel, Porto Vista Hotel Downtown, Hampton Inn San Diego-Downtown, Courtyard by Marriott San Diego Downtown Little Italy, The Pacific

Popular Luxury Stays in Little Italy

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