Book Hotels in Keowee, SC
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Top Keowee hotels

The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $221 total per night from Apr 12 to Apr 13
$221 total
Apr 12 - Apr 13
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
Limited menu available on site but many places nearby in walking distance.
Reviewed on Apr 1, 2026

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
299 Outpost Rd Seneca SC
$139 nightly
The price is $153 total per night from Apr 6 to Apr 7
$153 total
Apr 6 - Apr 7
Total with taxes and fees
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
Great spot for couples wanting to connect or a solo trip.
Reviewed on Apr 2, 2026

The Inn at Patrick Square
115 Market Street Clemson SC
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $176 total per night from Apr 6 to Apr 7
$176 total
Apr 6 - Apr 7
Total with taxes and fees
A 24-hour gym is featured at this hotel, along with free self parking. WiFi in public areas is free. Staff at the 24-hour front desk can provide around-the-clock ...
Clean room and lobby, friendly staff.
Reviewed on Apr 2, 2026

Clemson University's James F. Martin Inn
240 Madren Center Drive Clemson SC
$149 nightly
The price is $165 total per night from Apr 6 to Apr 7
$165 total
Apr 6 - Apr 7
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...
Love this place. We stay here every time we come to the area.
Reviewed on Apr 2, 2026

Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Apr 7 to Apr 8
$135 total
Apr 7 - Apr 8
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
Room was spacious and clean. Great pool. Close to campus.
Reviewed on Apr 4, 2026

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Apr 12 to Apr 13
$112 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Clean rooms, nice staff, free breakfast
Reviewed on Apr 3, 2026

Inn @ Clemson
1303 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $101 total per night from Apr 6 to Apr 7
$101 total
Apr 6 - Apr 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Breakfast was not so good. Have had better breakfast and breakfast choices!
Reviewed on Apr 3, 2026

Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
Fully refundable
$104 nightly
The price is $115 total per night from Apr 26 to Apr 27
$115 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
The room was fine. Nothing fancy but clean. The staff was very friendly and accommodating and the breakfast was great!!
Reviewed on Mar 27, 2026

Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Apr 12 to Apr 13
$65 total
Apr 12 - Apr 13
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Nice place to stay large rooms comfortable beds, I would strongly recommend this place to anybody passing through I85.
Reviewed on Apr 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Keowee hotel reviews by fellow wanderers

Days Inn by Wyndham Anderson
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Nice place to stay large rooms comfortable beds, I would strongly recommend this place to anybody passing through I85."
A verified traveler stayed at Days Inn by Wyndham Anderson
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