Book Hotels in Jefferson, SC

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Jefferson hotels

Springhill Suites by Marriott Cheraw

Springhill Suites by Marriott Cheraw

3 out of 5
201 Front Street Cheraw SC
$127 nightly
The price is $142 total per night from Jul 19 to Jul 20
$142 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like full breakfast and WiFi in public areas. ...
"The room was very clean. I did not like that the bed was so low to the floor as it felt like I was sleeping on the floor. The electric blinds were broke so we couldn’t lower them to darken the room. The shower leaked like a pond into the bathroom if you used the detachable shower head. The bar a ..."

Reviewed on Jul 13, 2026

Opens in a new windowSpringhill Suites by Marriott Cheraw
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

2.5 out of 5
203 East Carolina Ave. Hartsville SC
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $155 total per night from Jul 31 to Aug 1
$155 total
Jul 31 - Aug 1
Total with taxes and fees
This hotel features an outdoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A 24-hour ...
"We found the rooms to be spacious and comfortable With staff who were pleasant and welcoming upon arrival and throughout."

Reviewed on Jul 7, 2026

Opens in a new windowHampton Inn & Suites Hartsville
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

3 out of 5
200 S 4th St Hartsville SC
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $115 total per night from Jul 20 to Jul 21
$115 total
Jul 20 - Jul 21
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"The hotel needed better management as far as cleanliness and they lack the ability to make the guest aware of their amenities. We were looking forward to using the pool but they fail to mention that the pool wasn’t available due to maintenance issues. This was disappointing and I had to ask if they ..."

Reviewed on Jul 13, 2026

Opens in a new windowFairfield Inn by Marriott Hartsville
Quality Inn Cheraw

Quality Inn Cheraw

2.5 out of 5
885 Chesterfield Hwy Cheraw SC
Fully refundable
$69 nightly
The price is $78 total per night from Aug 2 to Aug 3
$78 total
Aug 2 - Aug 3
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
"The room was nice and clean. The pool needed a little bit of work, but it was still very relaxing.."

Reviewed on Jul 14, 2026

Opens in a new windowQuality Inn Cheraw
Baymont by Wyndham Cheraw

Baymont by Wyndham Cheraw

2.5 out of 5
710 Market St Cheraw SC
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $86 total per night from Jul 19 to Jul 20
$86 total
Jul 19 - Jul 20
Total with taxes and fees
A 24-hour gym is featured at this motel, along with free self parking. Guests will appreciate free perks like self-serve breakfast and WiFi in public areas. ...
"The staff was sweet and friendly; the room was clean."

Reviewed on Jul 12, 2026

Opens in a new windowBaymont by Wyndham Cheraw
Super 8 by Wyndham Lancaster

Super 8 by Wyndham Lancaster

2 out of 5
1201 Highway 9 Byp W Lancaster SC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Aug 2 to Aug 3
$76 total
Aug 2 - Aug 3
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"The wifi sig was too weak to use my Roku tv. I worked nights and during the day house keeping was really noisy with the cleaning cart, woke me every day. And no pool as advertised."

Reviewed on Jun 28, 2026

Opens in a new windowSuper 8 by Wyndham Lancaster
Days Inn by Wyndham Monroe NC

Days Inn by Wyndham Monroe NC

1.5 out of 5
1608 E. Roosevelt Blvd. Monroe NC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Aug 2 to Aug 3
$76 total
Aug 2 - Aug 3
Total with taxes and fees
A bar/lounge and a 24-hour front desk are featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast ...
"Horrible!!!! Nothing worked, room smelled awful, dead bugs in the room, refrigerator didn’t work. A waste of my money"

Reviewed on Jun 28, 2026

Opens in a new windowDays Inn by Wyndham Monroe NC
Rodeway Inn Monroe

Rodeway Inn Monroe

2 out of 5
611 W Roosevelt Blvd Monroe NC
Fully refundableReserve now, pay when you stay
$51 nightly
The price is $57 total per night from Jul 21 to Jul 22
$57 total
Jul 21 - Jul 22
Total with taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. Staff at the 24-hour ...
Opens in a new windowRodeway Inn Monroe
The Mantissa Hotel

The Mantissa Hotel

3 out of 5
130 East Carolina Ave Hartsville SC
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $202 total per night from Jul 20 to Jul 21
$202 total
Jul 20 - Jul 21
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...
Opens in a new windowThe Mantissa Hotel
Don't see what you're looking for?
See all available properties in Jefferson
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in Jefferson?
Family getaways are where amazing memories are made, but it's no secret that traveling with little ones can be a challenge. These kid-friendly Jefferson hotels offer perks that aim to keep young and old alike relaxed and happy: Your entourage will enjoy staying at Guest Lodge Pageland. Express check-out services and a picnic area are just a few of the things that help make this place a sought-after option. Also check out the deals at Remodeled historic house, near Pageland, with WI-FI and parking FREE. It comes with extra bedding, clothes washing facilities and lots of opportunities for precious family time.
Where can I find cheap hotels in Jefferson?
At Travelocity you'll find really nice hotels in Jefferson at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Jefferson rather than in Jefferson. We may find you even better rates, too.
How do I find the best Jefferson hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Jefferson then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Jefferson?
The cheapest hotel in Jefferson is $57. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Jefferson?
There are 85 hotels in Jefferson on Travelocity.
What are the best hotels in Jefferson?
Jefferson has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Jefferson for you!
When is the best time to visit Jefferson?
If you want the joy of a fun-filled trip in peak season, visit Jefferson during May, August and September. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Jefferson?
Based on historic data is usually the cheapest month to visit Jefferson. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Jefferson?
There are multiple hotels in Jefferson that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Jefferson. We have plenty of kid-friendly hotels in Jefferson to choose from on Travelocity!
Why book a hotel in Jefferson through Travelocity?
Because we have the top hotels in Jefferson! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Jefferson on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Jefferson hotel reviews by fellow wanderers

Quality Inn Cheraw

Quality Inn Cheraw

5 out of 5
Posted 21 hours ago
Travelocity Verified Review
"The room was nice and clean. The pool needed a little bit of work, but it was still very relaxing.."
A verified traveler stayed at Quality Inn Cheraw
Quality Inn Cheraw

Explore More Ways to Travel with Travelocity