Book Hotels in Jefferson, SC
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Top Jefferson hotels

Springhill Suites by Marriott Cheraw
201 Front Street, Cheraw, SC
$114 nightly
The price is $128 total per night from Oct 5 to Oct 6
$128 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like full breakfast and WiFi in public areas. ...
"Great room and hotel. Would definitely recommend and stay again."
Reviewed on Sep 26, 2025

Hampton Inn & Suites Hartsville
203 East Carolina Ave., Hartsville, SC
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $161 total per night from Oct 5 to Oct 6
$161 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features an outdoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A 24-hour ...
"Nice clean hotel. Comfortable beds, nice amenities."
Reviewed on Sep 28, 2025

The Mantissa Hotel
130 East Carolina Ave, Hartsville, SC
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $181 total per night from Oct 5 to Oct 6
$181 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...
"Room was clean, but had a funny smell. Rooftop bar is a plus!"
Reviewed on Sep 8, 2025

Fairfield Inn by Marriott Hartsville
200 S 4th St, Hartsville, SC
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from Oct 18 to Oct 19
$110 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"Staff was very friendly and helpful. The property is older, but for the most part has been maintained well."
Reviewed on Sep 13, 2025

Baymont by Wyndham Cheraw
710 Market St, Cheraw, SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $78 total per night from Sep 30 to Oct 1
$78 total
Sep 30 - Oct 1
Total with taxes and fees
A 24-hour gym is featured at this motel, along with free self parking. Guests will appreciate free perks like self-serve breakfast and WiFi in public areas. ...
"Nice"
Reviewed on Sep 10, 2025

Quality Inn Cheraw
885 Chesterfield Hwy, Cheraw, SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from Oct 12 to Oct 13
$71 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests ...
"Pool was dirty.. wouldn't swim in, curtains don't close... breakfast area was clean, rooms were rough.. ceiling in bathroom falling in. Personnel was nice"
Reviewed on Aug 24, 2025

Quality Inn Lancaster
114 Commerce Blvd, Lancaster, SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Oct 19 to Oct 20
$106 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
"I had to stay out of town for work and I believe it was the best I could find in that area"
Reviewed on Sep 17, 2025

The Landmark Inn
1301 South 4th Street, Hartsville, SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $93 total per night from Sep 30 to Oct 1
$93 total
Sep 30 - Oct 1
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Great staff"
Reviewed on Sep 16, 2025

Quality Inn
903 S 5th Street, Hartsville, SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from Oct 21 to Oct 22
$71 total
Oct 21 - Oct 22
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Business travelers can take advantage of the laundry ...
"Nice staff pet friendly!"
Reviewed on Sep 5, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Jefferson hotel reviews by fellow wanderers

Hampton Inn & Suites Hartsville
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Nice clean hotel. Comfortable beds, nice amenities."
A verified traveler stayed at Hampton Inn & Suites Hartsville
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