Book Hotels in Jefferson, SC
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Top Jefferson hotels

Springhill Suites by Marriott Cheraw
201 Front Street Cheraw SC
$118 nightly
The price is $132 total per night from Nov 30 to Dec 1
$132 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and free perks like full breakfast and WiFi in public areas. ...
yes
Reviewed on Nov 5, 2025

Hampton Inn & Suites Hartsville
203 East Carolina Ave., Hartsville, SC
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $134 total per night from Dec 5 to Dec 6
$134 total
Dec 5 - Dec 6
Total with taxes and fees
This hotel features an outdoor pool and a gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A 24-hour ...
Convenient location with large rooms and free breakfast!
Reviewed on Nov 4, 2025

The Mantissa Hotel
130 East Carolina Ave, Hartsville, SC
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $181 total per night from Nov 24 to Nov 25
$181 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Enjoy the a rooftop terrace and free perks like on-the-go breakfast and free self parking. A business ...
The location was conviene and the area was quite.
Reviewed on Oct 26, 2025

Fairfield Inn by Marriott Hartsville
200 S 4th St, Hartsville, SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $95 total per night from Nov 24 to Nov 25
$95 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
Wonderful staff and clean room
Reviewed on Nov 15, 2025

Baymont by Wyndham Cheraw
710 Market St Cheraw SC
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $84 total per night from Nov 18 to Nov 19
$84 total
Nov 18 - Nov 19
Total with taxes and fees
A 24-hour gym is featured at this motel, along with free self parking. Guests will appreciate free perks like self-serve breakfast and WiFi in public areas. ...
Rooms are modern and very clean! Staff was super friendly, and besides being the cheapest in a 50 mile radius, very well managed..alot of construction crews stay here, and very safe!
Reviewed on Oct 30, 2025

Quality Inn Lancaster
114 Commerce Blvd, Lancaster, SC
$89 nightly
The price is $100 total per night from Nov 23 to Nov 24
$100 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
Staff was friendly
Reviewed on Nov 11, 2025

Super 8 by Wyndham Lancaster
1201 Highway 9 Byp W, Lancaster, SC
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $81 total per night from Nov 28 to Nov 29
$81 total
Nov 28 - Nov 29
Total with taxes and fees
A restaurant and a seasonal outdoor pool are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Room was clean and ready. The staff was friendly.
Reviewed on Oct 31, 2025

Red Roof Inn & Suites Monroe, NC
608 West Roosevelt Blvd, STE E, Monroe, NC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $71 total per night from Nov 24 to Nov 25
$71 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the business center and onsite ...
Clean room and kind people at check in.
Reviewed on Oct 26, 2025

Quality Inn
903 S 5th Street, Hartsville, SC
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $64 total per night from Nov 30 to Dec 1
$64 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Business travelers can take advantage of the laundry ...
yes
Reviewed on Oct 30, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Jefferson hotel reviews by fellow wanderers

Fairfield Inn by Marriott Hartsville
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Wonderful staff and clean room"
A verified traveler stayed at Fairfield Inn by Marriott Hartsville
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