Find a Hotel in East Side Pioneers

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top hotels in East Side Pioneers

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

3.5 out of 5
10 East Center Street Rochester MN
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $197 total per night from Apr 3 to Apr 4
$197 total
Apr 3 - Apr 4
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
The room was lovely!

Reviewed on Mar 24, 2026

Opens in a new windowHilton Rochester Mayo Clinic Area
Aspen Suites

Aspen Suites

3 out of 5
1211 2nd Street Rochester MN
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Apr 2 to Apr 3
$175 total
Apr 2 - Apr 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Clean room, friendly staff. We would stay here again.

Reviewed on Mar 21, 2026

Opens in a new windowAspen Suites
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$93 nightly
The price is $107 total per night from Apr 4 to Apr 5
$107 total
Apr 4 - Apr 5
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Yes

Reviewed on Mar 23, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

Rochester MN
$198 nightly
The price is $228 total per night from Apr 12 to Apr 13
$228 total
Apr 12 - Apr 13
Total with taxes and fees
This vacation home featured laundry facilities and barbecue grills.
The house stunk of cigarette smoke and Marijuana when we arrived. It was not clean, and the host has been incredibly rude. I would strongly recommend avoiding this place.

Reviewed on Feb 14, 2026

Opens in a new windowDiscounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Rochester MN
$169 nightly
The price is $194 total per night from Mar 30 to Mar 31
$194 total
Mar 30 - Mar 31
Total with taxes and fees
This vacation home features laundry facilities.
Everything was perfect, couldn't ask for a better place to stay

Reviewed on Jan 5, 2026

Opens in a new windowDiscounted Charming 2-bedroom main-level TRIPLEX in Rochester
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $172 total per night from Mar 29 to Mar 30
$172 total
Mar 29 - Mar 30
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
You can walk to Mayo with out going outside. There is also a convenient store on the Subway level a few step from the elevater that has snacks, cold beverages and fresh popcorn. Walk a little farther and you can get Starbucks coffee. You can also get some Italian food from the best Italian restaurant ...

Reviewed on Mar 24, 2026

Opens in a new windowKahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $178 total per night from Mar 26 to Mar 27
$178 total
Mar 26 - Mar 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Great breakfast!

Reviewed on Mar 24, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

3 out of 5
15 1st Street Southeast Rochester MN
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $185 total per night from Apr 3 to Apr 4
$185 total
Apr 3 - Apr 4
Total with taxes and fees
This apartment features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's a hot tub ...
Opens in a new windowBroadway Plaza, Trademark Collection by Wyndham
Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

Rochester MN
This vacation home features laundry facilities.
Opens in a new windowNewly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
Don't see what you're looking for?
See all available properties in East Side Pioneers
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

East Side Pioneers Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on East Side Pioneers area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near East Side Pioneers to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near East Side Pioneers are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent East Side Pioneers hotel reviews by fellow wanderers