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Top hotels in East Side Pioneers

Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

Newly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.

Rochester MN
This vacation home features laundry facilities.
It was very comfortable and laundry on site awesome. Would definitely rent again for my mayo treatments..Updated throughout!!! MJ

Reviewed on Nov 27, 2025

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Opens in a new windowNewly remodeled "Beach" Themed home that is close to downtown and Mayo Clinic.
SUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO

SUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO

Rochester MN
This vacation home includes a garden and laundry facilities.
Host was amazing to work with. Nice older home but remodeled with modern twist. Loved the course proximity to Mayo.

Reviewed on Nov 26, 2025

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Opens in a new windowSUNNY 3BD, 2BA…ONLY BLOCKS FROM MAYO
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

3.5 out of 5
10 East Center Street Rochester MN
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $197 total per night from Dec 25 to Dec 26
$197 total
Dec 25 - Dec 26
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
Very courteous staff, loved the valet guy!

Reviewed on Dec 10, 2025

Opens in a new windowHilton Rochester Mayo Clinic Area
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

3 out of 5
15 1st Street Southeast Rochester MN
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $166 total per night from Dec 26 to Dec 27
$166 total
Dec 26 - Dec 27
Total with taxes and fees
This apartment features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's a hot tub ...
Great location. Kitchen is great.

Reviewed on Oct 29, 2025

Opens in a new windowBroadway Plaza, Trademark Collection by Wyndham
Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

Discounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!

Rochester MN
$173 nightly
The price is $199 total per night from Dec 23 to Dec 24
$199 total
Dec 23 - Dec 24
Total with taxes and fees
This vacation home featured laundry facilities and barbecue grills.
Lovely place to stay, before or after surgery. John was so nice answering questions and even stopping over when we needed something silly.

Reviewed on Nov 3, 2025

Opens in a new windowDiscounted Oasis! 5 Star-3 Bedroom Showstopping Duplex 4 Minutes to Mayo Clinic!
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$80 nightly
The price is $92 total per night from Dec 25 to Dec 26
$92 total
Dec 25 - Dec 26
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The room was nice, staff were friendly and the skyway to the Civic Center was great & very convenient! Would stay here again!

Reviewed on Dec 17, 2025

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Discounted Charming 2-bedroom house in Rochester

Discounted Charming 2-bedroom house in Rochester

Rochester MN
$168 nightly
The price is $193 total per night from Dec 20 to Dec 21
$193 total
Dec 20 - Dec 21
Total with taxes and fees
This vacation home features laundry facilities.
This is a lovely home … very clean and stocked with everything you need. It is shared with an upstairs and downstairs rental, which we did not know from the description. It was not a problem, but would have been nice to know. We accidentally opened the door on the side of the house to bring our stuff ...

Reviewed on Nov 5, 2025

Opens in a new windowDiscounted Charming 2-bedroom house in Rochester
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $172 total per night from Dec 20 to Dec 21
$172 total
Dec 20 - Dec 21
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Room was clean, rooftop, pool, and sauna was a great spot to relax. The convenience of walking around underground in the winter to get to stores and restaurants is genius! Check out at noon too! Only issue was we have a large truck

Reviewed on Dec 11, 2025

Opens in a new windowKahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $178 total per night from Dec 20 to Dec 21
$178 total
Dec 20 - Dec 21
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
We had a clean room, friendly staff and a large selection for breakfast.

Reviewed on Dec 15, 2025

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

East Side Pioneers Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on East Side Pioneers area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near East Side Pioneers to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near East Side Pioneers are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent East Side Pioneers hotel reviews by fellow wanderers

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"The room was nice, staff were friendly and the skyway to the Civic Center was great & very convenient! Would stay here again!"
A verified traveler stayed at Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG