Deals on vacations and trips to Depew

Save when you book Depew package deals

Choose two or more items and save on your trip:

Depew flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Downtown Buffalo
Price was $350, price is now $260 per person
$260
per person
Nov 8 - Nov 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to Buffalo (BUF)
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
Price was $394, price is now $279 per person
$279
per person
Dec 7 - Dec 9
found 1 day ago
Roundtrip flight included
Boston (BOS) to Buffalo (BUF)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy free perks like free self parking and an area shuttle.
THE 1023 With Private Yard & Parking, Near Falls & Casino by Niagara Hospitality

THE 1023 With Private Yard & Parking, Near Falls & Casino by Niagara Hospitality

3.5 out of 5
Save 100% on your flight
Price was $1,449, price is now $1,063 per person
$1,063
per person
Nov 27 - Nov 30
found 19 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Buffalo (BUF)
Free WiFi in public areas is available at this vacation home. Take advantage of the free self parking.
Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY

2.5 out of 5
Price was $446, price is now $335 per person
$335
per person
Dec 7 - Dec 9
found 1 day ago
Roundtrip flight included
Boston (BOS) to Buffalo (BUF)
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.
Niagara Crossing Hotel & Spa

Niagara Crossing Hotel & Spa

3.5 out of 5
Price was $756, price is now $577 per person
$577
per person
Nov 11 - Nov 17
found 4 hours ago
Roundtrip non-stop flight included
Houston (IAH) to Buffalo (BUF)
A full-service spa is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. A terrace, a lobby fireplace, and a computer station are also on offer.

Top Depew hotels deals

M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave, Buffalo, NY
Free Cancellation
Reserve now, pay when you stay
$81 nightly
The price is $92 total per night
$92 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Relax with a drink at the bar/lounge and enjoy free perks like buffet breakfast and free self parking.
Pool
Breakfast included
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St, Buffalo, NY
Free Cancellation
Reserve now, pay when you stay
$110 nightly
The price is $125 total per night
$125 total
Oct 6 - Oct 7
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy free perks like free self parking and an area shuttle.
Free airport shuttle
Parking included
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road, Buffalo, NY
Free Cancellation
Reserve now, pay when you stay
$105 nightly
The price is $120 total per night
$120 total
Nov 3 - Nov 4
Total with taxes and fees
This hotel features a 24-hour gym and a sauna. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Free train station pick-up is offered as well.
Free airport shuttle
Pet friendly
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza, Buffalo, NY
Free Cancellation
Reserve now, pay when you stay
$106 nightly
The price is $124 total per night
$124 total
Nov 3 - Nov 4
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.
Pool
Pet friendly
Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 out of 5
2761 Long Road, Grand Island, NY
Free Cancellation
$112 nightly
The price is $127 total per night
$127 total
Nov 3 - Nov 4
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.
Pool
Breakfast included
Comfort Inn & Suites Niagara Falls Blvd USA

Comfort Inn & Suites Niagara Falls Blvd USA

2.5 out of 5
6115 Niagara Falls Blvd, Niagara Falls, NY
Free Cancellation
Reserve now, pay when you stay
$84 nightly
The price is $96 total per night
$96 total
Nov 3 - Nov 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Depew
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

A nice day for a walk in the fall by the pillars. #universityatbuffalo#buffalo #ub #college #hiking #lake #berries #fall

University At Buffalo - North Campus

Explore the campus of University At Buffalo - North Campus, a top college in Amherst. Experience the area's entertainment choices and acclaimed theater scene.

University At Buffalo - North Campus
NFL Salute to Service Buffalo Bills Ralph Wilson Stadium

Highmark Stadium

Catch an event at Highmark Stadium during your trip to Orchard Park. Experience the area's great live music and entertainment choices.

Highmark Stadium
Buffalo Zoo

Buffalo Zoo

See more than 1,200 animals at this small zoo in Buffalo’s Delaware Park. Explore the rainforest building or see the big cats of the African plains.

Buffalo Zoo

Frequently asked questions

How much are vacation packages to Depew?
You'll find an excellent flight and hotel bundle for an affordable $260. With one of our Travelocity vacation packages, a stay in Depew has never been more tempting! Save some time and money and get an early start with packing your suitcases.
Where can I get the best vacation package deals for Depew?
It's hard to look past Travelocity when it comes to putting together your Depew package deal. There are at least 400 air carriers and 1,000,000 properties worldwide to choose from. Lock in your trip now and get ready to tick another amazing destination off your travel bucket list.
Why should I book my Depew vacation bundle with Travelocity?
Because you'll never roam alone if you book through us, and we offer 24/7 support and top-notch service to boot. Add to that our Price Match Guarantee and a huge range of destinations and experiences to pick from. We're here to help you have the vacation of a lifetime.
Will I save money on my Depew car rental if I bundle it with my hotel or flight?
Combining your hotel, flight and car into a Depew vacation package is the best way to score an amazing deal. Plus, having your own car rental gives you total freedom to find your way to all those amazing sights you're eager to see. Sitting 120 mi away from Depew, Conneaut Railroad Museum is one place that should be on your must-do list. Load up the car and make a day trip of it.
What is the best time of year to go to Depew?
If you'd prefer to avoid expensive airfares, tourist hordes and a lack of vacancy, arrange your trip outside of June, July and August. The quietest time to be in Depew is December, January and February. You'll find the highest hotel prices in and the most economical in .
Which airport is best for Depew?
For many wanderers, a trip to Depew means coming in to land at Buffalo Niagara Intl. Airport (BUF). This busy airport sits 3 mi northwest of the downtown area. You could also opt to fly into Greater Rochester Intl. Airport (ROC) (55 mi away from central Depew) or Chautauqua County Airport (JHW) (60 mi away from central Depew).
Where should I stay when visiting Depew?
Many visitors choose to stay at the Firemans Park Quarters. It's an excellent base for your Depew escape.

Photos of local treasures

Browse Depew vacation photos for more inspiration