Deals on vacations and trips to Depew

Save when you book Depew package deals

Choose two or more items and save on your trip:

Depew flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
Price was $493, price is now $349 per person
$349
per person
May 18 - May 22
found 2 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Buffalo (BUF)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy free perks like free self parking and an area shuttle.
The Mansion On Delaware Ave

The Mansion On Delaware Ave

4 out of 5
Downtown Buffalo
Save 100% on your flight
Price was $976, price is now $691 per person
$691
per person
May 18 - May 22
found 2 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Buffalo (BUF)
This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like cooked-to-order breakfast and free self parking.
Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel

5 out of 5
Downtown Buffalo
Save 100% on your flight
Price was $1,042, price is now $781 per person
$781
per person
May 18 - May 22
found 2 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Buffalo (BUF)
This smoke-free hotel features a full-service spa, hot springs, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like continental breakfast and free self parking.
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Downtown Buffalo
Price was $611, price is now $462 per person
$462
per person
May 18 - May 22
found 2 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Buffalo (BUF)
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.
Home2 Suites by Hilton Buffalo Airport / Galleria Mall

Home2 Suites by Hilton Buffalo Airport / Galleria Mall

3 out of 5
Price was $644, price is now $489 per person
$489
per person
May 18 - May 22
found 2 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Buffalo (BUF)
This hotel features an indoor pool and a gym. Free perks include buffet breakfast, free self parking, and a roundtrip airport shuttle. You'll appreciate the free area shuttle, free WiFi in public areas, and dry cleaning.

Top Depew hotels deals

Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
Free Cancellation
Reserve now, pay when you stay
$85 nightly
The price is $97 total per night
$97 total
Apr 30 - May 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy free perks like free self parking and an area shuttle.
Free airport shuttle
Parking included
Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 out of 5
2761 Long Road Grand Island NY
Free Cancellation
$109 nightly
The price is $124 total per night
$124 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like on-the-go breakfast and free self parking.
Pool
Breakfast included
M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
Free Cancellation
Reserve now, pay when you stay
$125 nightly
The price is $142 total per night
$142 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Relax with a drink at the bar/lounge and enjoy free perks like buffet breakfast and free self parking.
Pool
Breakfast included
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
Free Cancellation
Reserve now, pay when you stay
$79 nightly
The price is $90 total per night
$90 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features a 24-hour gym and a sauna. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. Free train station pick-up is offered as well.
Free airport shuttle
Pet friendly
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza Buffalo NY
$161 nightly
The price is $188 total per night
$188 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A bar/lounge, a 24-hour front desk, and a coffee shop are also provided.
Pool
Pet friendly
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
Free Cancellation
$73 nightly
The price is $83 total per night
$83 total
Apr 28 - Apr 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free self parking, and a free airport shuttle. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a gym on site, and laundry facilities and free newspapers are also offered.
Breakfast included
Free airport shuttle
Don't see what you're looking for?
See all available properties in Depew
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

University At Buffalo - North Campus

University At Buffalo - North Campus

4.5/5(110 reviews)

Enjoy the collegiate vibe when you visit University At Buffalo - North Campus, during your trip to Amherst. Experience the area's acclaimed theater scene and great live music.

University At Buffalo - North Campus
Highmark Stadium

Highmark Stadium

4/5(409 reviews)

Catch an event at Highmark Stadium during your trip to Orchard Park. Experience the area's great live music and entertainment choices.

Highmark Stadium
Downtown Buffalo NY

KeyBank Center

4.5/5(527 reviews)

Catch an event at KeyBank Center during your trip to Buffalo. Experience the area's great live music and entertainment choices.

KeyBank Center

Frequently asked questions

How much are vacation packages to Depew?
You'll find an excellent flight and hotel bundle for an affordable $349. With one of our Travelocity vacation packages, a stay in Depew has never been more tempting! Save some time and money and get an early start with packing your suitcases.
Where can I get the best vacation package deals for Depew?
It's hard to look past Travelocity when it comes to putting together your Depew package deal. There are at least 400 air carriers and 1,000,000 properties worldwide to choose from. Lock in your trip now and get ready to tick another amazing destination off your travel bucket list.
Why should I book my Depew vacation bundle with Travelocity?
Because you'll never roam alone if you book through us, and we offer 24/7 support and top-notch service to boot. Add to that our Price Match Guarantee and a huge range of destinations and experiences to pick from. We're here to help you have the vacation of a lifetime.
Will I save money on my Depew car rental if I bundle it with my hotel or flight?
Combining your hotel, flight and car into a Depew vacation package is the best way to score an amazing deal. Plus, having your own car rental gives you total freedom to find your way to all those amazing sights you're eager to see. Sitting 120 mi away from Depew, Conneaut Railroad Museum is one place that should be on your must-do list. Load up the car and make a day trip of it.
What is the best time of year to go to Depew?
If you'd prefer to avoid expensive airfares, tourist hordes and a lack of vacancy, arrange your trip outside of June, July and August. The quietest time to be in Depew is December, January and February. You'll find the highest hotel prices in and the most economical in .
Which airport is best for Depew?
For many wanderers, a trip to Depew means coming in to land at Buffalo Niagara Intl. Airport (BUF). This busy airport sits 3 mi northwest of the downtown area. You could also opt to fly into Greater Rochester Intl. Airport (ROC) (55 mi away from central Depew) or Chautauqua County Airport (JHW) (60 mi away from central Depew).
Where should I stay when visiting Depew?
Many visitors choose to stay at the Firemans Park Quarters. It's an excellent base for your Depew escape.

Photos of local treasures

Browse Depew vacation photos for more inspiration