Explore top 2026 5 Star Hotels in Mediterranean Region

Name: Barceló Torre de Madrid
Price range: $229 total
Rating: 9.4

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Top Mediterranean Region 5 Star hotels

Grand Hyatt Athens

115, Syngrou Avenue Athens Attica

Fully refundableReserve now, pay when you stay

$102 nightly

$121 total

Mar 16 - Mar 17

Total with taxes and fees

A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

8.8/10 Excellent! (1,090 reviews)

The rooftop pool was closed and were not able to make it to the spa or pool downstairs.

Reviewed on Mar 9, 2026

Sofitel Athens Airport

Athens International Airport Spata-Artemida Attiki

Fully refundableReserve now, pay when you stay

$266 nightly

$307 total

Mar 12 - Mar 13

Total with taxes and fees

A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.4/10 Exceptional! (2,646 reviews)

Didn’t park Didn’t use the Spa

Reviewed on Mar 9, 2026

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Avenida Catedral, 7 Barcelona

Fully refundable

$234 nightly

$277 total

Mar 11 - Mar 12

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, ...

9.4/10 Exceptional! (1,851 reviews)

Great location but NO air conditioning! Be prepared for a very warm room.

Reviewed on Mar 6, 2026

Electra Metropolis Athens

15 Mitropoleos Street Athens Attiki

Fully refundable

$239 nightly

$277 total

Mar 22 - Mar 23

Total with taxes and fees

A full-service spa, 2 restaurants, and an indoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...

9.8/10 Exceptional! (1,114 reviews)

Hospitality, quality, attentiveness…I could go on. They couldn’t do enough for you. The staff make this place the most enjoyable experience. The rooms were clean and well looked after with nice little touches and chocolate treat every day on your bed. Thank you. I will come again when I am in Athens. ...

Reviewed on Mar 8, 2026

Corinthia Lisbon

Avenida Columbano Bordalo Pinheiro, 105 Lisbon

Fully refundableReserve now, pay when you stay

$232 nightly

$256 total

Mar 11 - Mar 12

Total with taxes and fees

A full-service spa, 3 restaurants, and an indoor pool are all featured at this luxury hotel. Families will appreciate the children's pool, kid-friendly dining, ...

9.6/10 Exceptional! (1,237 reviews)

My stay at the Corinthia Lisbon was absolutely wonderful. From the moment I arrived, everything felt elegant, comfortable, and welcoming. The service was exceptional and the staff made sure every detail was taken care of. One of the highlights of my stay was the breakfast — it was truly outstanding. ...

Reviewed on Mar 6, 2026

Avenida Palace

Rua 1 De Dezembro 123 Lisbon

Fully refundableReserve now, pay when you stay

$300 nightly

$328 total

Mar 17 - Mar 18

Total with taxes and fees

This hotel features a gym and a bar/lounge. Guests will appreciate free perks like valet parking and WiFi in public areas. Free self parking, a business center, ...

9.8/10 Exceptional! (1,004 reviews)

A beautiful place to stay with wonderful staff and evening live piano music!

Reviewed on Feb 19, 2026

Grand Hyatt Barcelona

Plaza de Pio XII, 4 Barcelona

Fully refundableReserve now, pay when you stay

$198 nightly

$237 total

Mar 27 - Mar 28

Total with taxes and fees

A full-service spa, 2 restaurants, and a hot tub are all featured at this luxury hotel. Enjoy the gym and perks like free WiFi. You'll appreciate the seasonal ...

9.2/10 Wonderful! (1,500 reviews)

Amazing staff. Great energy and very thoughtful. It’s a beautiful hotel in a beautiful location. The food was great, the atmosphere was great … and did I mention the the staff was excellent 👌

Reviewed on Mar 8, 2026

Only YOU Hotel Sevilla

Avenida De Kansas City No.7 Seville Seville

Fully refundableReserve now, pay when you stay

$285 nightly

$314 total

Apr 6 - Apr 7

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9.8/10 Exceptional! (672 reviews)

This was the most perfect hotel I have stayed at. We traveled to Sevilla to visit our son who is studying there. The hotel was in close proximity to his housing and in walking distance to a shopping center as well as a football stadium. Our room was ready when we checked in, and were greeted with ...

Reviewed on Mar 9, 2026

Nobu Hotel Barcelona

Avenida de Roma 2-4 Barcelona Barcelona

Fully refundableReserve now, pay when you stay

$237 nightly

$279 total

Apr 8 - Apr 9

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi. ...

9/10 Wonderful! (1,239 reviews)

not go

Reviewed on Mar 8, 2026

Barceló Torre de Madrid

Plaza de España, 18 Madrid

Fully refundableReserve now, pay when you stay

$208 nightly

$229 total

Mar 15 - Mar 16

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...

9.4/10 Exceptional! (2,382 reviews)

It was ok

Reviewed on Mar 8, 2026

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Mediterranean Region Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Mediterranean Region to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Mediterranean Region 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Mediterranean Region before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.