Explore top 2026 4 Star Hotels in Santa Cruz

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Top Santa Cruz 4 Star hotels

TRYP by Wyndham Santa Cruz

Av. San Martin, Calle 9 Este Santa Cruz

$87 total

per night

Sep 14 - Sep 15

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Enjoy the gym and free perks like buffet breakfast and free self parking. There's a sauna ...

9.2/10 Wonderful! (177 reviews)

"We had a great stay here. The rooms were clean and comfortable. Will return!"

Reviewed on Sep 9, 2026

Camino Real Hotel

Av. San Martín y 4to. Anillo Santa Cruz

$127 total

per night

Oct 12 - Oct 13

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. There's fun for all ages with a children's pool and a waterslide, ...

9/10 Wonderful! (441 reviews)

"The food is excellent quality and delicious! Friendly staff"

Reviewed on Sep 7, 2026

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

San Martin Avenue Esq Street E - E Santa Cruz

$74 total

per night

Oct 2 - Oct 3

This hotel features a restaurant, a gym, and a bar/lounge. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...

9.2/10 Wonderful! (286 reviews)

"The room was very clean and the breakfast was fantastic. Overall it was a great experience."

Reviewed on Sep 5, 2026

Swissôtel Santa Cruz De La Sierra

5to anillo Avenida La Salle # 4500 Santa Cruz

$131 total

per night

Oct 2 - Oct 3

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...

9.2/10 Wonderful! (89 reviews)

"Hospedagem muito boa, hotel limpo e bem cuidado, café da manhã bom, funcionários atenciosos e prestativos. Recomendo."

Reviewed on Jul 13, 2026

Hotel Maywa

2do anillo av.santacruz #1007 Santa Cruz Santa Cruz Department

This hotel features a 24-hour gym and a rooftop terrace. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and airport ...

9.2/10 Wonderful! (10 reviews)

"The structure and service was fantastic"

Reviewed on Sep 17, 2025

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Buganvillas Hotel Suites & Spa

Av. Roca y Coronado No. 901 Santa Cruz

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool and barbecue grills. Enjoy the gym and perks ...

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Royal Lodge Hotel

Avenida San Martin 200 Santa Cruz

This hotel features an outdoor pool, a gym, and a restaurant. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Santa Cruz

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Santa Cruz 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Santa Cruz will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Santa Cruz, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.