
$199 Cheap American Airlines flights from Portland to Key West (PWM to EYW)
Find The Best Day To Fly from Portland to Key West
Amazing American Airlines PWM to EYW Flight Deals
The cheapest flights to Key West Intl. found within the past 7 days were $294 round trip and $199 one way. Prices and availability subject to change. Additional terms may apply.
EYW From PWM Economy Coach Packages on Similar Airlines



Frequently asked questions
Discover our best American Airlines flight from Portland PWM to Key West EYW
To find the best deals on flights to Portland from Key West with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Portland PWM to Key West EYW with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $294 to $359, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Portland PWM to Key West EYW
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Portland to Key West costs from $199. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to Key West EYW from Portland PWM with American Airlines
To find a cheap American Airlines flight from Portland PWM to Key West EYW, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Portland PWM to Key West EYW
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as December, or if you book a flight with a stopover.
Find nonstop flights from Portland PWM to Key West EYW with American Airlines
If you’re keen to be on Key West soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Portland PWM to Key West EYW
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to Key West EYW from Portland PWM with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Key West

Reviewed on Jul 9, 2025

Reviewed on Jul 9, 2025

Reviewed on Jul 9, 2025
Popular American Airlines Flight Routes from PWM
- American Airlines PWM to TPA
- American Airlines PWM to BWI
- American Airlines PWM to ORD
- American Airlines PWM to SJU
- American Airlines PWM to PHX
- American Airlines PWM to BNA
- American Airlines PWM to MBJ
- American Airlines PWM to RIC
- American Airlines PWM to RDU
- American Airlines PWM to IAH
- American Airlines PWM to PNS
Top American Airlines Flight Routes from EYW
Top Flights for American Airlines originating from PWM
Domestic
- Newark Liberty Intl. Airport to Fort Lauderdale (EWR - FLL)
- Chicago to Mexico City (ORD - MEX)
- New York to Santiago (JFK - STI)
- Chicago to Las Vegas (ORD - LAS)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Philadelphia to Orlando (PHL - MCO)
- New York to San Juan (JFK - SJU)
- San Juan to Orlando (SJU - MCO)
- Los Angeles to San Salvador (LAX - SAL)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
International
- New York to Santiago (JFK - STI)
- Newark Liberty Intl. Airport to Fort Lauderdale (EWR - FLL)
- New York to Santiago (JFK - STI)
- Newark Liberty Intl. Airport to Santo Domingo (EWR - SDQ)
- San Juan to Orlando (SJU - MCO)
- San Juan to Orlando (SJU - MCO)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Dallas to Las Vegas (DFW - LAS)
- Atlanta to Las Vegas (ATL - LAS)
- Chicago to Orlando (ORD - MCO)
Most Popular
- Atlanta to Miami (ATL - MIA)
- Philadelphia to Miami (PHL - MIA)
- JetBlue Airways Boston (BOS) to Orlando (MCO) flights
- JetBlue Airways Orlando (MCO) to Las Vegas (LAS) flights
- Boston to Miami (BOS - MIA)
- New York to Fort Lauderdale (JFK - FLL)
- New York to Tampa (JFK - TPA)
- Raleigh to Orlando (RDU - MCO)
- Baltimore to Orlando (BWI - MCO)
- Chicago to Orlando (ORD - MCO)
- Los Angeles to Orlando (LAX - MCO)
- Los Angeles to Miami (LAX - MIA)
- Minneapolis to Orlando (MSP - MCO)
- Dallas to Orlando (DFW - MCO)
- Detroit to Miami (DTW - MIA)
- Orlando to San Juan (MCO - SJU)
- JetBlue Airways Boston (BOS) to Fort Lauderdale (FLL) flights
- Baltimore to Miami (BWI - MIA)
- New York to Orlando (JFK - MCO)
- New York to Miami (JFK - MIA)
- Hawaiian Airlines Orlando (MCO) to Honolulu (HNL) flights
- Philadelphia to Tampa (PHL - TPA)
- Philadelphia to Orlando (PHL - MCO)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Orlando to Atlanta (MCO - ATL)
- Detroit to Orlando (DTW - MCO)
- Dallas to Miami (DFW - MIA)
- Hartford to Orlando (BDL - MCO)
- Cleveland to Orlando (CLE - MCO)
- Atlanta to Orlando (ATL - MCO)