
$256 Cheap American Airlines flights from Des Moines to McAllen (DSM to MFE)
Find The Best Day To Fly from Des Moines to McAllen
Amazing American Airlines DSM to MFE Flight Deals
The cheapest flights to Miller Intl. found within the past 7 days were $284 round trip and $256 one way. Prices and availability subject to change. Additional terms may apply.
MFE From DSM Economy Coach Packages on Similar Airlines



Frequently asked questions
Discover our best American Airlines flight from Des Moines DSM to McAllen MFE
To find the best deals on flights to Des Moines from McAllen with American Airlines, just enter your travel dates, filter by American Airlines, and hit search. You’ll find flights to choose from and can sort by price, flight duration, and arrival or departure time.
Return flights from Des Moines DSM to McAllen MFE with American Airlines
If you’re planning a round trip, booking return flights with American Airlines is usually the most cost-effective option. With airfares ranging from $284 to $348, it’s easy to find a flight that suits your budget. Prices and availability subject to change. Additional terms may apply.
Book one-way American Airlines flights from Des Moines DSM to McAllen MFE
A one-way ticket gives you much greater flexibility—allowing you to choose your return date, destination, and time whenever you’re ready. By booking in advance you can find great deals on one-way tickets too. Right now, a one-way American Airlines flight from Des Moines to McAllen costs from $256. Prices and availability subject to change. Additional terms may apply.
The easy way to find cheap flights to McAllen MFE from Des Moines DSM with American Airlines
To find a cheap American Airlines flight from Des Moines DSM to McAllen MFE, sort your search results by price or filter by budget. Thanks to Travelocity’s Price Match Promise, if you find a better airfare deal anywhere else within 24 hours, we’ll credit or refund the difference.
How to find our best airfare deals on American Airlines flights from Des Moines DSM to McAllen MFE
If you’re looking for cheap flights, it helps to be flexible when it comes to your travel dates. You’ll usually find lower cost tickets when you travel during quieter months such as May, or if you book a flight with a stopover.
Find nonstop flights from Des Moines DSM to McAllen MFE with American Airlines
If you’re keen to be on McAllen soil fast, don’t waste time with a stopover—filter your search results to show direct American Airlines flights only. The journey takes around hour(s) min(s) – so you’ll be there before you know it.
Flexible airline tickets for American Airlines flights from Des Moines DSM to McAllen MFE
Make sure you’re not out of pocket if plans change by choosing a flexible ticket with penalty-free amendment and cancellation options. Use our ‘no change fee’ filter to see which flights have this option.
There are a lot of reasons to book your flights to McAllen MFE from Des Moines DSM with American Airlines on Travelocity
At Travelocity our vast and up-to-the-minute inventory puts all of our best flight deals in one place. So, whether you’re traveling on business or jetting off with friends and family, you can trust Travelocity to get you there.
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
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More Ways To Wander
Popular American Airlines Flight Routes from DSM
Top American Airlines Flight Routes from MFE
Top Flights for American Airlines originating from DSM
Domestic
- San Francisco to Tokyo (SFO - HND)
- San Juan to Orlando (SJU - MCO)
- New York to San Juan (JFK - SJU)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)
- Chicago to Las Vegas (ORD - LAS)
- Seattle to Tokyo (SEA - NRT)
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- Newark Liberty Intl. Airport to Miami (EWR - MIA)
- San Francisco to Tokyo (SFO - NRT)
- Philadelphia to Orlando (PHL - MCO)
International
- New York to Montego Bay (JFK - MBJ)
- Lisbon to Toronto (LIS - YYZ)
- Seattle to Tokyo (SEA - HND)
- New York to Santiago (JFK - STI)
- Seattle to Tokyo (SEA - NRT)
- San Juan to Orlando (SJU - MCO)
- Newark Liberty Intl. Airport to Santiago (EWR - STI)
- New York to San Juan (JFK - SJU)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Newark Liberty Intl. Airport to Orlando (EWR - MCO)