
$180 Cheap American Airlines flights from Columbia to San Diego (CAE to SAN)
Find The Best Day To Fly from Columbia to San Diego
Amazing American Airlines CAE to SAN Flight Deals
The cheapest flights to San Diego Intl. found within the past 7 days were $333 round trip and $180 one way. Prices and availability subject to change. Additional terms may apply.
CAE
Columbia
SAN
San Diego
$333 Roundtrip, found 1 day ago
$333
Roundtrip
found 1 day ago
CAE
Columbia
SAN
San Diego
$357 Roundtrip, found 1 day ago
$357
Roundtrip
found 1 day ago
Frequently asked questions
Travelers ❤️ these 🏨 after their flight to San Diego

Sheraton San Diego Resort
1380 Harbor Island Dr, San Diego, CA
A marina, 5 restaurants, and 3 outdoor pools are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi ...
8/10 Very Good! (2,821 reviews)
"I would go back"
Reviewed on Jul 14, 2025

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, express check-out, and ...
8.2/10 Very Good! (5,705 reviews)
"Great property. Convenient to walk and go to places"
Reviewed on Jul 16, 2025

Handlery Hotel
950 Hotel Cir N, San Diego, CA
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
8/10 Very Good! (1,881 reviews)
"Really enjoyed our stay. Great service and very clean"
Reviewed on Jul 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular American Airlines Flight Routes from CAE
Top American Airlines Flight Routes from SAN
Domestic
- New York to Las Vegas (JFK - LAS)
- Dallas to Las Vegas (DFW - LAS)
- Atlanta to Las Vegas (ATL - LAS)
- Chicago to Las Vegas (ORD - LAS)
- Philadelphia to Orlando (PHL - MCO)
- Los Angeles to Honolulu (LAX - HNL)
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Los Angeles to Honolulu (LAX - HNL)
- San Juan to Orlando (SJU - MCO)
- Dallas to Las Vegas (DFW - LAS)
International
- Newark Liberty Intl. Airport to Las Vegas (EWR - LAS)
- Newark Liberty Intl. Airport to San Juan (EWR - SJU)
- Los Angeles to Honolulu (LAX - HNL)
- Orlando to San Juan (MCO - SJU)
- Los Angeles to San Salvador (LAX - SAL)
- Boston to Orlando (BOS - MCO)
- Orlando to San Juan (MCO - SJU)
- New York to Las Vegas (JFK - LAS)
- New York to Santiago (JFK - STI)
- Philadelphia to Orlando (PHL - MCO)
Most Popular
Flights
- PHL to MIA Flights
- JetBlue Airways Boston (BOS) to Orlando (MCO) flights
- LAX to ORD Flights
- LAX to LHR Flights
- BOS to MIA Flights
- JetBlue Airways Boston (BOS) to Las Vegas (LAS) flights
- DFW to ATL Flights
- LAX to CDG Flights
- LAX to MCO Flights
- BOS to LAX Flights
- LAX to MIA Flights
- LAX to HNL Flights
- Delta Atlanta (ATL) to Las Vegas (LAS) flights
- DFW to MCO Flights
- LAX to DFW Flights
- LAX to JFK Flights
- SFO to LAX Flights
- JFK to LAX Flights
- DFW to ORD Flights
- ATL to LAX Flights
- Delta Minneapolis - St. Paul (MSP) to Las Vegas (LAS) flights
- SFO to JFK Flights
- PHL to MCO Flights
- Air India San Francisco (SFO) to Delhi (DEL) flights
- LAX to BOS Flights
- Delta Detroit (DTW) to Las Vegas (LAS) flights
- ORD to LAX Flights
- JFK to SFO Flights
- LAX to SFO Flights
- DFW to LAX Flights