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Top hotels in Serenity Bay

Perfect Summer get away! Charming 4 bedroom lake front home.

Perfect Summer get away! Charming 4 bedroom lake front home.

Seneca SC
This vacation home features a garden, laundry facilities, and barbecue grills.
House is well furnished and stocked with all the supplies needed for a restful time.

Reviewed on Aug 24, 2025

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Opens in a new windowPerfect Summer get away! Charming 4 bedroom lake front home.
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson SC
Free WiFi in public areas is available at this cottage.
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Opens in a new windowWooded Cottage - 3 Mi to Clemson University
Serenity Bay Lakefront Cabin w/ Boat Slip.

Serenity Bay Lakefront Cabin w/ Boat Slip.

Seneca SC
This vacation home featured laundry facilities and barbecue grills.
The house was great, clean and well maintained. Was nice to have the gas grill and we really enjoyed our time there.

Reviewed on Oct 23, 2025

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Opens in a new windowSerenity Bay Lakefront Cabin w/ Boat Slip.
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $210 total per night from Jan 25 to Jan 26
$210 total
Jan 25 - Jan 26
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...
A very comfortable hotel. Our only complaint is that our room was on the second floor, right below the bar and on weekend nights we could hear the partying upstairs. An otherwise excellent stay. No self parking, either valet or Uber. Very walkable location, restaurants, bars and shops nearby. The ...

Reviewed on Jan 19, 2026

Opens in a new windowThe Shepherd Hotel Downtown Clemson
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

3 out of 5
240 Madren Center Drive Clemson SC
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $165 total per night from Jan 25 to Jan 26
$165 total
Jan 25 - Jan 26
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...
Clean rooms, location and restaurant

Reviewed on Dec 20, 2025

Opens in a new windowClemson University's James F. Martin Inn
Lakeside Lodge Clemson

Lakeside Lodge Clemson

2.5 out of 5
13500 Clemson Blvd Seneca SC
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Jan 24 to Jan 25
$135 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Enjoy the seasonal outdoor pool and perks like free self parking and free WiFi. You'll appreciate ...
We booked this hotel because the hot tub is open during the winter. Our 1 BR suite was large and in excellent condition. We did not try the restaurant but heard good things about it. Some reviews we have seen complained about train noises. Apparently, they have resolved that issue - didn't hear a ...

Reviewed on Jan 19, 2026

Opens in a new windowLakeside Lodge Clemson
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $105 total per night from Jan 26 to Jan 27
$105 total
Jan 26 - Jan 27
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The staff especially stood out. The online check in and the front desk was an absolute breeze! I am pleased as all heck. The room was clean and is well laid out for me to work. I greatly appreciate it.

Reviewed on Jan 5, 2026

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

2.5 out of 5
1305 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $106 total per night from Feb 2 to Feb 3
$106 total
Feb 2 - Feb 3
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...
Clean room. Friendly staff. Convenient location.

Reviewed on Jan 17, 2026

Opens in a new windowComfort Inn & Suites Clemson - University Area
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 out of 5
226 Hi Tech Rd Seneca SC
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Jan 29 to Jan 30
$92 total
Jan 29 - Jan 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
Our stay was very nice. Clean room. The outside was clean.

Reviewed on Jan 20, 2026

Opens in a new windowQuality Inn Seneca Clemson Area US-123
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Serenity Bay Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Serenity Bay area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Serenity Bay to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Serenity Bay are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Serenity Bay hotel reviews by fellow wanderers

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Our stay was very nice. Clean room. The outside was clean. "
A verified traveler stayed at Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123

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