Upstate South Carolina Vacation Packages 2026 from $456

Upstate South Carolina flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Home2 Suites by Hilton Charlotte Mooresville

Save 100% on your flight

$456

per person

Apr 1 - Apr 8

just found

Roundtrip flight included

New York (JFK) to Charlotte (CLT)

This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate freebies like buffet breakfast and free self parking.

Landing Apartments - Northlake

Save 100% on your flight

$699

per person

Apr 1 - Apr 8

just found

Roundtrip flight included

New York (JFK) to Charlotte (CLT)

This aparthotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A business center, a lobby fireplace, and barbecue grills are also on offer.

The Westin Charlotte

Uptown Charlotte

Save 100% on your flight

$515

per person

Feb 27 - Mar 2

found 1 day ago

Roundtrip flight included

New York (JFK) to Charlotte (CLT)

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Self parking, a snack bar/deli, and express check-out are also offered.

The Windsor Boutique Hotel

Downtown Asheville

$659

per person

Mar 26 - Mar 29

found 1 day ago

Roundtrip flight included

Chicago (ORD) to Asheville (AVL)

This hotel features a bar/lounge, free WiFi in public areas, and a snack bar/deli. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Luggage storage, laundry facilities, and concierge services are also on offer.

The Foundry Hotel Asheville, Curio Collection by Hilton

Downtown Asheville

$645

per person

Mar 26 - Mar 29

found 1 day ago

Roundtrip flight included

Chicago (ORD) to Asheville (AVL)

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A coffee shop, a terrace, and a garden are also on offer.

Top Upstate South Carolina hotels deals

Hilton Greenville

45 W Orchard Park Dr Greenville SC

Free Cancellation

Reserve now, pay when you stay

$100 nightly

$110 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, and laundry service. Self parking, a terrace, and a garden are also offered.

Pet friendly

Free WiFi

Embassy Suites Greenville Golf Resort & Conference Center

670 Verdae Blvd Greenville SC

Free Cancellation

Reserve now, pay when you stay

$94 nightly

$104 total

Jan 25 - Jan 26

Total with taxes and fees

A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the outdoor pool and free buffet breakfast each morning.

Pool

Breakfast included

Wooded Cottage - 3 Mi to Clemson University

Clemson SC

Get rates

Free WiFi in public areas is available at this cottage.

Kitchen

Pet friendly

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY Greenville SC

Free Cancellation

Reserve now, pay when you stay

$235 nightly

$258 total

Jan 25 - Jan 26

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. Valet parking, a lobby fireplace, and a communal living room are also offered.

Spa

Pet friendly

Hampton Inn & Suites Greenville-Downtown-RiverPlace

171 Riverplace Greenville SC

Free Cancellation

Reserve now, pay when you stay

$134 nightly

$147 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a 24-hour gym and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the free buffet breakfast each morning.

Breakfast included

Pet friendly

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

11 Ketron Court Greenville SC

Free Cancellation

Reserve now, pay when you stay

$82 nightly

$91 total

Jan 23 - Jan 24

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center and free internet in public areas. A garden, a picnic area, and a computer station are also on offer.

Breakfast included

Pet friendly

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Clemson University

5/5(410 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

Falls Park on the Reedy

4.5/5(583 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.

Entrance to stadium and tradition. #footballstadiumtours

Memorial Stadium

5/5(129 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.

Frequently asked questions

How much are vacation packages to Upstate South Carolina?

$456 is all you need to spend for an exhilarating break in Upstate South Carolina. Bundle your hotel and flights into a vacation package with Travelocity and watch how the savings start to pile up. With prices this good, you'll want to start packing your suitcase now!

Where can I get the best vacation package deals for Upstate South Carolina?

For an amazing Upstate South Carolina package deal, you can't go past Travelocity. Take your pick of 400 air carriers and 1,000,000 properties worldwide to create your dream escape — the choice is all yours!

Why should I purchase my Upstate South Carolina vacation bundle with Travelocity?

With our Price Match Guarantee, we'll match any better price you can find. Add to that our 24/7 support and top-quality service and the vacation you've been dreaming of is well within reach.

Can I save money on my Upstate South Carolina car rental if I bundle it with a hotel or flight?

You sure can. And our Upstate South Carolina vacation packages are the ideal way to do it. In only a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car then chart your own course. Searching for things to do? Throw some tours or experiences into your package and save on those too.

Which airport is best for Upstate South Carolina?

Upstate South Carolina has two major airports — Greenville-Spartanburg Intl. Airport (GSP) and Asheville Regional Airport (AVL).

What is there to do in Upstate South Carolina?

You'll be happy to know Upstate South Carolina is full to the brim with incredible photo opportunities, however Clemson University and Lake Keowee are right up there with the very best.