Explore beach hotels in Otay Mesa, CA from $113

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top Otay Mesa Beach Resorts & Hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2296 Niels Bohr Ct San Diego CA
Fully refundable
$129 nightly
The price is $147 total per night from Nov 23 to Nov 24
$147 total
Nov 23 - Nov 24
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
8/10 Very Good! (1,534 reviews)
Nice

Reviewed on Nov 15, 2025

Opens in a new windowHoliday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa

2351 Otay Center Dr San Diego CA
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $113 total per night from Nov 20 to Nov 21
$113 total
Nov 20 - Nov 21
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate ...
7/10 Good! (1,002 reviews)
good

Reviewed on Oct 21, 2025

Opens in a new windowQuality Suites San Diego Otay Mesa
Don't see what you're looking for?
See all available properties in Otay Mesa
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular Beach Stays in Otay Mesa

Hotels with pools in Otay Mesa
Hotels with pools
Hotels with pools
Vacation rentals with pools in Otay Mesa
Vacation rentals with pools
Vacation rentals with pools
Pet-friendly beach stays in Otay Mesa
Pet-friendly beach stays
Pet-friendly beach stays

Recent Otay Mesa Hotel Reviews By Fellow Wanderers

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Staff was great Our suite was extremely nice the sound system was great. Gaslamp area was great lots of great food."
A verified traveler from Oakland stayed at Hard Rock Hotel San Diego
Hard Rock Hotel San Diego

Explore More Ways to Travel with Travelocity