Explore beach hotels in Otay Mesa, CA from $113
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Top Otay Mesa Beach Resorts & Hotels
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct San Diego CA
Fully refundable
$119 nightly
The price is $135 total per night from Jan 11 to Jan 12
$135 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
8/10 Very Good! (1,575 reviews)
Yes
Reviewed on Jan 2, 2026
Quality Suites San Diego Otay Mesa
2351 Otay Center Dr San Diego CA
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $113 total per night from Jan 11 to Jan 12
$113 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will appreciate ...
7/10 Good! (1,010 reviews)
We stayed one night for an early flight out to Guadalajara. It was clean and quiet so no major complaints.
Reviewed on Jan 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Beach Condos in Otay Mesa
Location! Location! Location!
San Diego CA
9.8/10 Exceptional! (313 reviews)
Beach Villas in Otay Mesa
Gorgeous Beach Villa -- Ocean Views + Sleeps 12!
San Diego CA
10/10 Exceptional! (10 reviews)
Popular Beach Stays in Otay Mesa
Recent Otay Mesa Hotel Reviews By Fellow Wanderers
Hard Rock Hotel San Diego
5 out of 5
Posted 17 hours ago
Travelocity Verified Review
"great"
A verified traveler stayed at Hard Rock Hotel San Diego
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