Book Hotels in Irene, SD
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Top Irene hotels

Gavins Point Lakehouse
Yankton
This vacation home includes a garden and laundry facilities.
Simply Stunning
"Property was stunning. Views from the home are stunning and the memories we made were u forgettable. Beds and pillows were all comfortable and the kitchen was stocked with the tools to allow you to prepare whatever upur heart desired. Communication was simple and responses were quick. Definitely ..."
Reviewed on Aug 3, 2025

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET, Yankton, SD
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $169 total per night from Aug 31 to Sep 1
$169 total
Aug 31 - Sep 1
Total includes taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
"Bath tub would not hold water. Shower curtain difficult to close so water would not go all over floor."
Reviewed on Aug 8, 2025

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave, Yankton, SD
Fully refundable
$123 nightly
The price is $135 total per night from Sep 7 to Sep 8
$135 total
Sep 7 - Sep 8
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Bed and piloows were superb"
Reviewed on Aug 4, 2025

Lewis and Clark Resort
43496 Shore Drive, Yankton, SD
$104 nightly
The price is $110 total per night from Sep 2 to Sep 3
$110 total
Sep 2 - Sep 3
Total includes taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
"Its the best place around the lake"
Reviewed on Aug 5, 2025

Comfort Inn Yankton SD
611 W 23rd Street, Yankton, SD
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $117 total per night from Sep 4 to Sep 5
$117 total
Sep 4 - Sep 5
Total includes taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
"Loved it here. Super safe and great staff."
Reviewed on Jul 7, 2025

Best Western Kelly Inn
1607 E Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $117 total per night from Aug 31 to Sep 1
$117 total
Aug 31 - Sep 1
Total includes taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Clean rooms, great service"
Reviewed on Aug 10, 2025

Yankton Inn
1603 East Highway 50, Yankton, SD
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $94 total per night from Aug 31 to Sep 1
$94 total
Aug 31 - Sep 1
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
Impressive for newly renovated motel
"Overall, it was quite good for the newly renovated motel, which previously resembled a Super 8. Everything is very convenient. Just that the water pressure for the shower might need some gain. :-)"
Reviewed on Jul 7, 2025

Econo Lodge Inn & Suites
2410 Broadway Ave, Yankton, SD
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $96 total per night from Aug 17 to Aug 18
$96 total
Aug 17 - Aug 18
Total includes taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Work in progress
"Hotel is mostly clean but they have some way to get a very good rating a lot of stuff still going on to get it in top shape but I think they will get it done"
Reviewed on Aug 6, 2025

Super 8 by Wyndham Beresford
1410 W Cedar St, Hwy 46 & I-29, Beresford, SD
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $68 total per night from Aug 12 to Aug 13
$68 total
Aug 12 - Aug 13
Total includes taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. Staff at the 24-hour ...
"It was ok"
Reviewed on Jul 23, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Irene hotel reviews by fellow wanderers

Best Western Kelly Inn
5 out of 5
Posted 18 hours ago
Travelocity Verified Review
"Clean rooms, great service"
A verified traveler stayed at Best Western Kelly Inn
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