Book Hotels in Irene, SD
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Top Irene hotels

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET Yankton SD
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $131 total per night from Jan 11 to Jan 12
$131 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like continental breakfast and WiFi in public areas. ...
New, very nice. Friendly staff. Convenient location.
Reviewed on Dec 13, 2025

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave Yankton SD
$106 nightly
The price is $117 total per night from Jan 14 to Jan 15
$117 total
Jan 14 - Jan 15, 2026
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
Yes, clean room
Reviewed on Dec 9, 2025

Spacious Lakeview Cabin Minutes from Private Beach
Crofton NE
This cabin featured laundry facilities and barbecue grills.
The host was great and the stay was better!
Reviewed on Nov 10, 2025

Comfort Inn Yankton SD
611 W 23rd Street Yankton SD
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $98 total per night from Jan 11 to Jan 12
$98 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
This hotel features a gym and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies ...
Yes, all the above
Reviewed on Dec 22, 2025

Lewis and Clark Resort
43496 Shore Drive Yankton SD
$94 nightly
The price is $99 total per night from Dec 28 to Dec 29
$99 total
Dec 28 - Dec 29
Total with taxes and fees
A marina and a restaurant are featured at this hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference center, and conference ...
Rooms are clean, no frills, place is quiet. Nicely priced. Way better than a hotel.
Reviewed on Dec 9, 2025

Best Western Kelly Inn
1607 E Highway 50 Yankton SD
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $109 total per night from Jan 4 to Jan 5
$109 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Very comfortable room and quiet we luv staying at your hotel oyr dog luvs it too breakfast is wonderful also luv hit tub!!!
Reviewed on Dec 4, 2025

Yankton Inn
1603 East Highway 50 Yankton SD
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $86 total per night from Dec 28 to Dec 29
$86 total
Dec 28 - Dec 29
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide ...
Clean room, low pet fee, quiet.
Reviewed on Dec 4, 2025

Econo Lodge Inn & Suites
2410 Broadway Ave Yankton SD
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from Dec 29 to Dec 30
$90 total
Dec 29 - Dec 30
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
Yes the room was clean staff was great
Reviewed on Dec 18, 2025

Super 8 by Wyndham Beresford
1410 W Cedar St Beresford SD
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $70 total per night from Dec 28 to Dec 29
$70 total
Dec 28 - Dec 29
Total with taxes and fees
This motel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free on-the-go breakfast each morning. Staff at the 24-hour ...
Easy check in from online reservation last minute. Room was clean, toilet was really wobbly and breakfast was ok.
Reviewed on Dec 8, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Irene hotel reviews by fellow wanderers

Comfort Inn Yankton SD
5 out of 5
Posted 8 days ago
Travelocity Verified Review
"Very clean room. Odor free."
A verified traveler stayed at Comfort Inn Yankton SD
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