Book Hotels in Carlisle, SC
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Top Carlisle hotels

A Taste of Southern Comfort
Carlisle SC
A gym is featured at this vacation home, along with laundry facilities and barbecue grills.
Welcome to SC
This was my first opportunity to live in SC and everything was great and I wanted for nothing, I would recommend this house if you want tranquility in the evening
Reviewed on Jun 28, 2025

Holiday Inn Express Richburg by IHG
3190 COMMERCE DRIVE Richburg SC
Fully refundable
$88 nightly
The price is $99 total per night from Apr 19 to Apr 20
$99 total
Apr 19 - Apr 20
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Guests will appreciate freebies like full breakfast and free self parking. A 24-hour business center, ...
I booked this hotel for the pool, when we checked in I was told the pool is closed until July. They need to take it off the amenities until it’s opened back up.
Reviewed on Apr 4, 2026

Holiday Inn Express & Suites Newberry by IHG
121 Truman Ave Newberry SC
Fully refundable
$122 nightly
The price is $132 total per night from May 4 to May 5
$132 total
May 4 - May 5
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Clean room, great breakfast
Reviewed on Apr 4, 2026

Hampton Inn Newberry-Opera House
1201 Nance St Newberry SC
$125 nightly
The price is $138 total per night from Apr 26 to Apr 27
$138 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an outdoor pool and a gym. There's no skimping on freebies - guests receive free continental breakfast, free WiFi, and free self parking. ...
Very nice room and staff was very helpful. Great breakfast!
Reviewed on Apr 1, 2026

Comfort Suites Clinton near Presbyterian College
12865 Hwy 56 N Clinton SC
Fully refundable
$106 nightly
The price is $119 total per night from May 2 to May 3
$119 total
May 2 - May 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Ice machines did not work. Power went out. Room Smelled. Attendant was wandering, parking his car in the check-in area, and dispondant (not helpful. This hotel is not worth any more of my time commenting...
Reviewed on Mar 24, 2026

Quality Inn Clinton - Laurens I-26
105 Trade St Clinton SC
Fully refundableReserve now, pay when you stay
$56 nightly
The price is $63 total per night from May 2 to May 3
$63 total
May 2 - May 3
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
The particular room I had was spotless, clean and without any fragrances. The bed and sheets and pillows appeared to be almost new and very, very comfortable.
Reviewed on Mar 21, 2026

Days Inn by Wyndham Richburg
3217 Lancaster Hwy Richburg SC
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $67 total per night from Apr 6 to Apr 7
$67 total
Apr 6 - Apr 7
Total with taxes and fees
An outdoor pool is featured at this motel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. ...
The comforter had so many holes. Towels were dirty in the bathroom. Chair sooo stained, it was gross.
Reviewed on Apr 3, 2026

Days Inn by Wyndham Clinton / Laurens I-26
12374 Highway 56 N Clinton SC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Apr 19 to Apr 20
$76 total
Apr 19 - Apr 20
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
The room was half clean. A dirty cloth was still on the shower rod and tangerine was left in refrigerator. I said I didn't care if it was a smoking or non smoking room and ended up in a smoking room. It was if someone was smoking right next to me.
Reviewed on Apr 2, 2026

Hampton Inn & Suites Clinton - I-26
201 E Corporate Center Drive Clinton SC
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $140 total per night from Apr 21 to Apr 22
$140 total
Apr 21 - Apr 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 3 conference rooms, free WiFi in public areas, and express check-in. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Carlisle hotel reviews by fellow wanderers

Holiday Inn Express & Suites Newberry by IHG
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Clean room, great breakfast "
A verified traveler stayed at Holiday Inn Express & Suites Newberry by IHG
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