Explore 34 Luxury Hotels in San Luis Obispo Wine Country

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Best Luxury Hotels in San Luis Obispo Wine Country

Avila La Fonda Hotel

Avila La Fonda Hotel

101 San Miguel St Avila Beach CA
Fully refundableReserve now, pay when you stay
$233 nightly
The price is $263 total per night from Apr 22 to Apr 23
$263 total
Apr 22 - Apr 23
Total with taxes and fees
This hotel features free WiFi in public areas, laundry facilities, and free self parking. Enjoy the free continental breakfast each morning. A snack bar/deli, ...
9.6/10 Exceptional! (1,000 reviews)
Loved my experience and the location. My room was perfect, enjoyed the hot tub and proximity to the beach. Also, was felt extra spoiled by all the extra goodies the staff wouldn’t stop giving us…will be back!!

Reviewed on Mar 14, 2026

Opens in a new windowAvila La Fonda Hotel
San Luis Creek Lodge

San Luis Creek Lodge

1941 Monterey Street San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$215 nightly
The price is $244 total per night from Apr 12 to Apr 13
$244 total
Apr 12 - Apr 13
Total with taxes and fees
This bed & breakfast doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Express check-out is also provided.
9.4/10 Exceptional! (1,000 reviews)
A/C worked but the room felt cold even with our adjustments to it. Towels were old, rugs dirty, doors dirty, small fridge didn't keep anything cold. Staff was froendly but property needs touch-ups.

Reviewed on Mar 14, 2026

Opens in a new windowSan Luis Creek Lodge
Madonna Inn

Madonna Inn

100 Madonna Road San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $283 total per night from Mar 30 to Mar 31
$283 total
Mar 30 - Mar 31
Total with taxes and fees
A full-service spa, 2 restaurants, and 2 outdoor tennis courts are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour ...
9.2/10 Wonderful! (1,394 reviews)
My little family always comes here when were in the area, but usually just to dine. This was our first time staying and we were lucky enough to get the Safari Room. This room was really awesome and we were very comfortable. Staff is always super helpful. We will be back for sure. Thanks for the awesome ...

Reviewed on Mar 23, 2026

Opens in a new windowMadonna Inn
Avenue Inn Downtown San Luis Obispo

Avenue Inn Downtown San Luis Obispo

345 Marsh St San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $82 total per night from Mar 24 to Mar 25
$82 total
Mar 24 - Mar 25
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A grocery/convenience store, express check-out, and luggage storage are ...
9/10 Wonderful! (1,202 reviews)
They had no beds available larger than a twin. The air-conditioning in the room didn’t work well and was louder than a jet engine. By the time I returned from dinner, there was no parking on the property Thank goodness the weather was decent so I could sleep with an open window because if I had to ...

Reviewed on Mar 23, 2026

Opens in a new windowAvenue Inn Downtown San Luis Obispo
La Cuesta Inn, BW Signature Collection

La Cuesta Inn, BW Signature Collection

2074 Monterey Street San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $132 total per night from Mar 30 to Mar 31
$132 total
Mar 30 - Mar 31
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. Express ...
8.8/10 Excellent! (1,045 reviews)
Omar and Dave were friendly, welcoming and helped orient me to the area.

Reviewed on Mar 18, 2026

Opens in a new windowLa Cuesta Inn, BW Signature Collection
Vagabond Inn San Luis Obispo

Vagabond Inn San Luis Obispo

210 Madonna Rd San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $92 total per night from Mar 24 to Mar 25
$92 total
Mar 24 - Mar 25
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. Business travelers can take advantage of the express check-out. A restaurant, ...
8.4/10 Very Good! (1,277 reviews)
Pool was closed with a small amount of stagnant dirty water which attracted tons of mosquitoes. Room had a STRONG smell of poop, I called the office, manager seemed annoyed saying he'll send housekeeping then promptly hanged up on me. Once the housekeeper arrived they seemed more interested in who ...

Reviewed on Mar 23, 2026

Opens in a new windowVagabond Inn San Luis Obispo
Inn at San Luis Obispo

Inn at San Luis Obispo

1895 Monterey Street San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $65 total per night from Apr 14 to Apr 15
$65 total
Apr 14 - Apr 15
Total with taxes and fees
This motel features an outdoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...
7.6/10 Good! (1,002 reviews)
The curtains were ripped. They should throw them away. The room has a stinch moldy smell. If I would have known it was in such bad condition I would never rented it. The online pictures is a lie. The people above my room were up all night walking back and forth. I complained to front desk but he ...

Reviewed on Mar 23, 2026

Opens in a new windowInn at San Luis Obispo
Hotel Calle Joaquin

Hotel Calle Joaquin

1585 Calle Joaquin San Luis Obispo CA
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $77 total per night from Mar 24 to Mar 25
$77 total
Mar 24 - Mar 25
Total with taxes and fees
This hotel features an outdoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self parking, ...
7.4/10 Good! (783 reviews)
This place is a solid 6.8/10. Fits your needs if you're in a pinch, otherwise I wouldn't bother.

Reviewed on Mar 22, 2026

Opens in a new windowHotel Calle Joaquin
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More 4 star hotels in San Luis Obispo Wine Country

San Luis Obispo Wine Country Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the San Luis Obispo Wine Country luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in San Luis Obispo Wine Country to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in San Luis Obispo Wine Country will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in San Luis Obispo Wine Country, and plan your next opulent escape.


San Luis Obispo Wine Country hotels essential information

Accommodation
1,863 hotels
Lowest Price
$65
Highest Price
$283
Popular hotels
Madonna Inn, Avenue Inn Downtown San Luis Obispo, Avila La Fonda Hotel, Hotel Calle Joaquin, San Luis Creek Lodge, La Cuesta Inn, BW Signature Collection, Vagabond Inn San Luis Obispo, Inn at San Luis Obispo

Popular Luxury Stays in San Luis Obispo Wine Country

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