Explore top 2025 5 Star Hotels in Mediterranean Region

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Top Mediterranean Region 5 Star hotels

Grand Hyatt Athens

Grand Hyatt Athens

5 out of 5
115, Syngrou Avenue, Athens, Attica
$148 nightly
The price is $186 total per night from Oct 26 to Oct 27
$186 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...
8.6/10 Excellent! (853 reviews)
"Amazing pool with a view of the acropolis, great option of a free shuttle into the centre although a 40 minute walk otherwise. Very safe area"

Reviewed on Sep 23, 2025

Opens in a new windowGrand Hyatt Athens
Sofitel Athens Airport

Sofitel Athens Airport

5 out of 5
Athens International Airport, Spata-Artemida, Attiki
Fully refundableReserve now, pay when you stay
$283 nightly
The price is $326 total per night from Nov 1 to Nov 2
$326 total
Nov 1 - Nov 2
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.4/10 Exceptional! (2,713 reviews)
"Clean room, easy check in and out, location great for airport use."

Reviewed on Sep 29, 2025

Opens in a new windowSofitel Athens Airport
Lamaro Hotel

Lamaro Hotel

5 out of 5
Avenida Catedral, 7, Barcelona
Fully refundableReserve now, pay when you stay
$381 nightly
The price is $438 total per night from Oct 19 to Oct 20
$438 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, ...
9.4/10 Exceptional! (1,809 reviews)
"Great for walking to shops and restaurants"

Reviewed on Sep 25, 2025

Opens in a new windowLamaro Hotel
Grand Hyatt Barcelona

Grand Hyatt Barcelona

5 out of 5
Plaza de Pio XII, 4, Barcelona
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $211 total per night from Oct 31 to Nov 1
$211 total
Oct 31 - Nov 1
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this luxury hotel. Enjoy the gym and perks like free WiFi. Enjoy the seasonal outdoor ...
9.2/10 Wonderful! (1,405 reviews)
"Clean room, nice facility staff excellent"

Reviewed on Sep 29, 2025

Opens in a new windowGrand Hyatt Barcelona
Corinthia Lisbon

Corinthia Lisbon

5 out of 5
Avenida Columbano Bordalo Pinheiro, 105, Lisbon
Fully refundableReserve now, pay when you stay
$268 nightly
The price is $293 total per night from Nov 1 to Nov 2
$293 total
Nov 1 - Nov 2
Total with taxes and fees
A full-service spa, 3 restaurants, and an indoor pool are all featured at this luxury hotel. Families will appreciate the children's pool, kid-friendly dining, ...
9.4/10 Exceptional! (1,207 reviews)
"The hotel was excellent. The staff, from the porters at the entrance, the check-in staff and the dining staff were very personable and helpful. The accommodation was beautiful. We were not able to use the spa benefit, but it was a nice option. There is a Metro stop a five minute walk away, which ..."

Reviewed on Sep 29, 2025

Opens in a new windowCorinthia Lisbon
InterContinental Barcelona by IHG

InterContinental Barcelona by IHG

5 out of 5
Avenida Ruis I Taulet 1-3, Barcelona
Fully refundable
$242 nightly
The price is $286 total per night from Oct 31 to Nov 1
$286 total
Oct 31 - Nov 1
Total with taxes and fees
A full-service spa, 2 restaurants, and a gym are all featured at this luxury hotel. Traveling on business? Take advantage of the business center and free WiFi ...
9.2/10 Wonderful! (1,014 reviews)
"Excellent stay and staff very helpful, would stay again. Location good and with walking distance to main attractions."

Reviewed on Sep 21, 2025

Opens in a new windowInterContinental Barcelona by IHG
Athenaeum InterContinental by IHG

Athenaeum InterContinental by IHG

5 out of 5
89-93 Syngrou Avenue, Athens, Attiki
Fully refundable
$149 nightly
The price is $187 total per night from Oct 26 to Oct 27
$187 total
Oct 26 - Oct 27
Total with taxes and fees
A full-service spa, 3 restaurants, and a 24-hour gym are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities and in-room ...
9/10 Wonderful! (1,010 reviews)
"This was a great place to stay however, I came during a hot part of the summer and the pool was not available. This would’ve been fine had I been made to know to this prior to my arrival. My party was tired from a super long trip. I thought I would just spend the day swimming while I waited for them ..."

Reviewed on Sep 12, 2025

Opens in a new windowAthenaeum InterContinental by IHG
Nobu Hotel Barcelona

Nobu Hotel Barcelona

5 out of 5
Avenida de Roma 2-4, Barcelona, Barcelona
Fully refundableReserve now, pay when you stay
$254 nightly
The price is $299 total per night from Nov 1 to Nov 2
$299 total
Nov 1 - Nov 2
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi. ...
8.8/10 Excellent! (1,112 reviews)
"Good location near placa catalunya, transit metro and 3km or less walk to Gothic quarter and La Boqueria. All staff were exrra friendly and helpful. The hosuekeeping staff werer truly great. The view from the rooftop patio is divine.bravo.will come and stay again."

Reviewed on Sep 29, 2025

Opens in a new windowNobu Hotel Barcelona
Barceló Torre de Madrid

Barceló Torre de Madrid

5 out of 5
Plaza de España, 18, Madrid
Fully refundable
$233 nightly
The price is $256 total per night from Oct 19 to Oct 20
$256 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9.4/10 Exceptional! (2,162 reviews)
"property was in a great location. Very friendly staff, beautiful and clean rooms. Great Breakfast."

Reviewed on Sep 25, 2025

Opens in a new windowBarceló Torre de Madrid
Akra Antalya

Akra Antalya

5 out of 5
Lara Yolu, Antalya, Antalya
Fully refundableReserve now, pay when you stay
$187 nightly
The price is $210 total per night from Nov 1 to Nov 2
$210 total
Nov 1 - Nov 2
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and 3 restaurants. Enjoy a day at the beach scuba diving, or relax with beach umbrellas. Relax ...
9.2/10 Wonderful! (1,450 reviews)
"I love to travel and rarely return to the same hotel, Akra Antalya is a notable exception. I'm also not one to leave reviews often, but after years of experiencing their exceptional service, I feel compelled to share my experience. In the recent years, I've found it increasingly difficult to discover ..."

Reviewed on Sep 29, 2025

Opens in a new windowAkra Antalya
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Mediterranean Region Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Mediterranean Region to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Mediterranean Region 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Mediterranean Region before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Mediterranean Region hotel reviews by fellow wanderers