Explore top 2026 5 Star Hotels in Mediterranean Region

Name: Eurostars Grand Marina
Price range: $192 total
Rating: 8.8

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Top Mediterranean Region 5 Star hotels

Grand Hyatt Athens

115, Syngrou Avenue Athens Attica

Fully refundableReserve now, pay when you stay

$86 nightly

$103 total

Feb 5 - Feb 6

Total with taxes and fees

A full-service spa, an indoor pool, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free ...

8.6/10 Excellent! (1,035 reviews)

Everything was very good

Reviewed on Jan 16, 2026

Lamaro Hotel

Avenida Catedral, 7 Barcelona

Fully refundable

$259 nightly

$304 total

Feb 8 - Feb 9

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 2 conference rooms, free WiFi in public areas, ...

9.4/10 Exceptional! (1,846 reviews)

Everything was perfect! Raining days, but wonderful place and pretty nice staff. Thank you guys

Reviewed on Jan 19, 2026

Hyatt Regency Barcelona Tower

Gran Via 144 L'Hospitalet de Llobregat

Fully refundableReserve now, pay when you stay

$136 nightly

$158 total

Feb 8 - Feb 9

Total with taxes and fees

This luxury hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Enjoy the seasonal outdoor pool and perks like free WiFi. Self parking, a business ...

8.8/10 Excellent! (1,017 reviews)

Our room was spotless, panoramic view, courteous staff, live entertainment

Reviewed on Jan 15, 2026

The Palace, a Luxury Collection Hotel, Madrid

Plaza de las Cortes, 7 Madrid Madrid

Fully refundableReserve now, pay when you stay

$383 nightly

$421 total

Jan 30 - Jan 31

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9/10 Wonderful! (1,004 reviews)

Very good.

Reviewed on Jan 5, 2026

Barceló Torre de Madrid

Plaza de España, 18 Madrid

Fully refundable

$203 nightly

$223 total

Feb 8 - Feb 9

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9.4/10 Exceptional! (2,312 reviews)

Great

Reviewed on Jan 18, 2026

Only YOU Hotel Sevilla

Avenida De Kansas City No.7 Seville Seville

Fully refundableReserve now, pay when you stay

$155 nightly

$171 total

Feb 3 - Feb 4

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...

9.6/10 Exceptional! (611 reviews)

Great location, clean, & staff

Reviewed on Jan 19, 2026

Sofitel Athens Airport

Athens International Airport Spata-Artemida Attiki

Fully refundableReserve now, pay when you stay

$256 nightly

$295 total

Feb 10 - Feb 11

Total with taxes and fees

A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.4/10 Exceptional! (2,615 reviews)

The price paid for the stay really do reflect the excellent accommodation condition and services they provide. Room air conditioning sound level is excellent compared to other big building hotels I've stayed in before. Facilities such as toilet is second to none. Swimming/dipping pool and sauna is ...

Reviewed on Jan 16, 2026

Nobu Hotel Barcelona

Avenida de Roma 2-4 Barcelona Barcelona

Fully refundableReserve now, pay when you stay

$233 nightly

$276 total

Feb 18 - Feb 19

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi. ...

8.8/10 Excellent! (1,208 reviews)

Property is beautiful and the staff was exceptionally friendly and service oriented.

Reviewed on Jan 18, 2026

Majestic Hotel & Spa Barcelona

Passeig De Gracia, 68 Barcelona

Fully refundableReserve now, pay when you stay

$312 nightly

$363 total

Feb 9 - Feb 10

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in ...

9.2/10 Wonderful! (1,001 reviews)

Room was very clean, staff is amazing. The location is the best part of all. Just don't do laundry their lol

Reviewed on Jan 15, 2026

Eurostars Grand Marina

Moll De Barcelona S/n Barcelona

$157 nightly

$192 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport ...

8.8/10 Excellent! (1,194 reviews)

Staff were great, room was great, very convenient for the cruise port, shuttle bus stop only a couple of hundred yards away

Reviewed on Jan 16, 2026

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Mediterranean Region Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Mediterranean Region to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Mediterranean Region 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Mediterranean Region before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.