Explore top 2026 5 Star Hotels in Central West End

Name: Four Seasons Hotel St Louis
Price range: $380 total
Rating: 9.4

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Top Central West End 5 Star hotels

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO

$499 nightly

$583 total

Mar 15 - Mar 16

Total with taxes and fees

This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (559 reviews)

Excellent staff! I was upgraded to a deluxe room from a standard at check-in. Servers and bartenders were kind and helpful and the food and drinks were delicious.

Reviewed on Mar 13, 2026

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

Fully refundableReserve now, pay when you stay

$325 nightly

$380 total

Mar 16 - Mar 17

Total with taxes and fees

A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...

9.4/10 Exceptional! (1,001 reviews)

Top notch in every way. From the moment you walk in, it’s what you would expect from a 5-Star Hotel. Highly recommended.

Reviewed on Mar 9, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.