Explore top 2026 4 Star Hotels in Anderson

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Top Anderson 4 Star hotels

The Abernathy of Clemson

157 Old Greenville Hwy Clemson SC

Fully refundableReserve now, pay when you stay

$140 nightly

$156 total

Nov 16 - Nov 17

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free self ...

The Shepherd Hotel Downtown Clemson

110 Sloan St Clemson SC

Fully refundableReserve now, pay when you stay

$209 nightly

$232 total

Oct 28 - Oct 29

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and luggage storage are also ...

Liberty Hall Bed and Breakfast

621 S Mechanic St Pendleton SC

$140 nightly

$156 total

Oct 30 - Oct 31

Total with taxes and fees

This bed & breakfast features free WiFi in public areas, concierge services, and free self parking. Enjoy the free full breakfast each morning. A garden, express ...

Designer Retreat w/ Pool, Golf + Beach Access!

Salem SC

This apartment doesn't skimp on freebies - guests receive free WiFi and free self parking. An outdoor pool and barbecue grills are also provided.

10/10 Exceptional! (1 review)

Solo Hiking Trip

"Property is in a great community, and it was very clean and beautifully decorated."

Reviewed on Sep 19, 2023

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Wooded Keowee Key Retreat Near Golf & Trails

Salem SC

A marina and an outdoor pool are featured at this smoke-free apartment. Guests will appreciate free perks like free self parking and WiFi in public areas.

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Lake Keowee Condo: Resort Pools & Lake Access!

Salem SC

A marina and an outdoor pool are featured at this smoke-free apartment. Business travelers can take advantage of the free WiFi in public areas. Take advantage ...

10/10 Exceptional! (2 reviews)

"Wow!! Absolutely beautiful property. Recent remodel with beautiful and very tasteful design. Amazingly clean, organized and tidy. We are from Denver and did not have exposure to Lake Keowee. The lake was beautiful with great walking trails on the property. Special and spectacular spot! We will definitely ..."

Reviewed on Oct 4, 2026

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Lake Hartwell Frank Howard Home Clemson

7008 SC-187 Anderson SC

Stay at this vacation home in Anderson. Enjoy free WiFi, free parking, and cable TV channels. Popular attractions Memorial Stadium and Woodburn are located ...

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Keowee Key Condo w/ Lake Access & Community Pools!

Salem SC

A marina and an outdoor pool are featured at this smoke-free apartment. Business travelers can take advantage of the free WiFi in public areas. Take advantage ...

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Salem Vacation Rental w/ Lake Keowee Access!

Salem SC

A marina and an outdoor pool are featured at this smoke-free apartment. Families will appreciate the arcade/game room and barbecue grills. Enjoy the gym and ...

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Views, Pools & Marina: Lake Keowee Condo!

Salem SC

An outdoor pool is featured at this apartment, along with free WiFi in public areas.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Anderson

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Anderson 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Anderson will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Anderson, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.