Upstate South Carolina Vacation Packages 2026 from $486

Upstate South Carolina flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Hotel Hartness

$486

per person

Aug 19 - Aug 22

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Greenville (GSP)

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. There's a bar/lounge on site, and concierge services and wedding services are also provided.

The Windsor Boutique Hotel

Downtown Asheville

Save 100% on your flight

$983

per person

Aug 17 - Aug 22

just found

Roundtrip non-stop flight included

Hartford (BDL) to Asheville (AVL)

This hotel features a bar/lounge, free WiFi in public areas, and a snack bar/deli. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Luggage storage, laundry facilities, and concierge services are also on offer.

The Restoration Asheville

Downtown Asheville

Save 100% on your flight

$991

per person

Aug 17 - Aug 22

just found

Roundtrip non-stop flight included

Hartford (BDL) to Asheville (AVL)

This smoke-free hotel's 3 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. There's fun for all ages with a bowling alley and an arcade/game room. Enjoy the a rooftop terrace and free perks like continental breakfast and an area shuttle.

The Highlands at Sugar

Save 100% on your flight

$624

per person

Aug 29 - Sep 5

found 1 day ago

Roundtrip flight included

Denver (DEN) to Asheville (AVL)

This apartment features an indoor pool and a gym. There's fun for all ages with a playground and an arcade/game room, and barbecue grills are available on site. Enjoy the hot tub and perks like free self parking and free WiFi.

Fox Run at Lake Lure

Save 100% on your flight

$797

per person

Sep 5 - Sep 12

found 10 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Asheville (AVL)

A full-service spa, a water park, and 3 hot tubs are all featured at this luxury aparthotel. Bring the family and enjoy the lazy river, children's pool, and playground. Enjoy the indoor pool and perks like free self parking.

Top Upstate South Carolina hotels deals

Hilton Greenville

45 W Orchard Park Dr Greenville SC

Free Cancellation

Reserve now, pay when you stay

$117 nightly

$129 total

Jul 26 - Jul 27

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, and laundry service. Self parking, a terrace, and a garden are also offered.

Hyatt Regency Greenville

220 N Main St Greenville SC

Free Cancellation

Reserve now, pay when you stay

$157 nightly

$172 total

Jul 19 - Jul 20

Total with taxes and fees

This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a seasonal outdoor pool on site, and concierge services and wedding services are also offered.

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY Greenville SC

Free Cancellation

Reserve now, pay when you stay

$361 nightly

$396 total

Aug 3 - Aug 4

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A lobby fireplace, a communal living room, and dry cleaning are also on offer.

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

Free Cancellation

Reserve now, pay when you stay

$82 nightly

$91 total

Jul 19 - Jul 20

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

Free Cancellation

Reserve now, pay when you stay

$95 nightly

$106 total

Jul 15 - Jul 16

Total with taxes and fees

This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free self parking, a grocery/convenience store, and express check-out are also offered.

Embassy Suites Greenville Golf Resort & Conference Center

670 Verdae Blvd Greenville SC

$98 nightly

$107 total

Aug 2 - Aug 3

Total with taxes and fees

A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the outdoor pool and free buffet breakfast each morning.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Walk around the campus of Clemson University, a top university in Clemson. Experience the area's theater scene or attend a football game.

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Frequently asked questions

How much are vacation packages to Upstate South Carolina?

$486 is all you need to spend for an exhilarating break in Upstate South Carolina. Bundle your hotel and flights into a vacation package with Travelocity and watch how the savings start to pile up. With prices this good, you'll want to start packing your suitcase now!

Where can I get the best vacation package deals for Upstate South Carolina?

For an amazing Upstate South Carolina package deal, you can't go past Travelocity. Take your pick of 400 air carriers and 1,000,000 properties worldwide to create your dream escape — the choice is all yours!

Why should I purchase my Upstate South Carolina vacation bundle with Travelocity?

With our Price Match Guarantee, we'll match any better price you can find. Add to that our 24/7 support and top-quality service and the vacation you've been dreaming of is well within reach.

Can I save money on my Upstate South Carolina car rental if I bundle it with a hotel or flight?

You sure can. And our Upstate South Carolina vacation packages are the ideal way to do it. In only a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car then chart your own course. Searching for things to do? Throw some tours or experiences into your package and save on those too.

Which airport is best for Upstate South Carolina?

Upstate South Carolina has two major airports — Greenville-Spartanburg Intl. Airport (GSP) and Asheville Regional Airport (AVL).

What is there to do in Upstate South Carolina?

You'll be happy to know Upstate South Carolina is full to the brim with incredible photo opportunities, however Clemson University and Lake Keowee are right up there with the very best.