Explore 50 Luxury Hotels in Southern Minnesota

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Best Luxury Hotels in Southern Minnesota

Brentwood Inn & Suites

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $127 total per night from Jun 26 to Jun 27
$127 total
Jun 26 - Jun 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
8.8/10 Excellent! (1,006 reviews)
"The Brentwood is our favorite hotel to stay at when we are visiting the Mayo Clinic! Although it isn't as new as some of the other nearby hotels, our rooms are always clean and well maintained. I'll admit some of the building appears shopworn, it is still a great place to stay. Parking is available ..."

Reviewed on Jun 14, 2026

Opens in a new windowBrentwood Inn & Suites
Kahler Grand Hotel

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$158 nightly
The price is $182 total per night from Jul 15 to Jul 16
$182 total
Jul 15 - Jul 16
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
8.4/10 Very Good! (2,159 reviews)
"The rooms were really dated and dark. Felt like it wasn’t taken care of as well as other hotels in its price range."

Reviewed on Jun 14, 2026

Opens in a new windowKahler Grand Hotel
AmericInn by Wyndham Northfield

AmericInn by Wyndham Northfield

1320 Bollenbacher Dr Northfield MN
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $120 total per night from Jun 21 to Jun 22
$120 total
Jun 21 - Jun 22
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
8.4/10 Very Good! (661 reviews)
"Pool and hot tub were nice and warm!"

Reviewed on Jun 4, 2026

Opens in a new windowAmericInn by Wyndham Northfield
Super 8 by Wyndham Jackson MN

Super 8 by Wyndham Jackson MN

2025 Highway 71 N Jackson MN
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $105 total per night from Jun 21 to Jun 22
$105 total
Jun 21 - Jun 22
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
8/10 Very Good! (618 reviews)
"Looking to return for another stay"

Reviewed on Jun 14, 2026

Opens in a new windowSuper 8 by Wyndham Jackson MN
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $183 total per night from Jun 15 to Jun 16
$183 total
Jun 15 - Jun 16
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
8/10 Very Good! (1,594 reviews)
"The room was clean and comfortable, the staff was friendly and helpful, the breakfast was wonderful, and the parking was deeply appreciated. No question that next time, and there will be one, we'll stay at the Kahler Inn."

Reviewed on Jun 11, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
AmericInn by Wyndham Blue Earth

AmericInn by Wyndham Blue Earth

1495 Domes Dr Blue Earth MN
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $98 total per night from Jul 5 to Jul 6
$98 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
7.8/10 Good! (492 reviews)
"You could never find some someone to help you the didn’t have. Hot tub like they said they do pool was not very clean. No towels."

Reviewed on Jun 9, 2026

Opens in a new windowAmericInn by Wyndham Blue Earth
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $91 total per night from Jun 16 to Jun 17
$91 total
Jun 16 - Jun 17
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
7.8/10 Good! (1,025 reviews)
"Desk clerk did not greet us and was indifferent with our disappointment that the room we reserved months in advance was occupied. No information was given about breakfast, hot tub being out of order or location of the elevators. Just a shrug and " down that way". Toilet was installed on an angle ..."

Reviewed on Jun 14, 2026

Opens in a new windowMed City Inn & Suites - Mayo Clinic Area
Coratel Inn & Suites By Jasper Northfield

Coratel Inn & Suites By Jasper Northfield

1420 Riverview Dr Northfield MN
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $73 total per night from Jun 25 to Jun 26
$73 total
Jun 25 - Jun 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
6.2/10 (679 reviews)
"Close to St Olaf"

Reviewed on May 29, 2026

Opens in a new windowCoratel Inn & Suites By Jasper Northfield
Don't see what you're looking for?
See all available properties in Southern Minnesota
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southern Minnesota Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southern Minnesota luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southern Minnesota to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southern Minnesota will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southern Minnesota, and plan your next opulent escape.


Southern Minnesota hotels essential information

Accommodation
1,175 hotels
Lowest Price
$73
Highest Price
$183
Popular hotels
Kahler Grand Hotel, AmericInn by Wyndham Blue Earth, Med City Inn & Suites - Mayo Clinic Area, AmericInn by Wyndham Northfield, Super 8 by Wyndham Jackson MN, Coratel Inn & Suites By Jasper Northfield, Kahler Inn and Suites - Mayo Clinic Area, Brentwood Inn & Suites

Popular Luxury Stays in Southern Minnesota

Recent Southern Minnesota Hotel Reviews By Fellow Wanderers

Explore More Ways to Travel with Travelocity