Explore 50 Luxury Hotels in Southern Minnesota

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Best Luxury Hotels in Southern Minnesota

Brentwood Inn & Suites

Brentwood Inn & Suites

123 Fourth Ave. NW, Rochester, MN
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $144 total per night from Oct 24 to Oct 25
$144 total
Oct 24 - Oct 25
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
8.6/10 Excellent! (1,004 reviews)
MAYO October 2025
I stayed here due to appointments at MAYO. The location and subway access were key amenities in my decision to stay there.

Reviewed on Oct 14, 2025

Opens in a new windowBrentwood Inn & Suites
Kahler Grand Hotel

Kahler Grand Hotel

20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $148 total per night from Nov 5 to Nov 6
$148 total
Nov 5 - Nov 6
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
8.2/10 Very Good! (1,683 reviews)
Staff was incredible

Reviewed on Oct 22, 2025

Opens in a new windowKahler Grand Hotel
AmericInn by Wyndham Northfield

AmericInn by Wyndham Northfield

1320 Bollenbacher Dr, Northfield, MN
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Nov 16 to Nov 17
$112 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
8.2/10 Very Good! (613 reviews)
Great. Mikayla was fantastic she was so nice and made sure we had everything we needed. Traveling with little ones is no easy feat. They had a nice breakfast and it was very clean

Reviewed on Oct 13, 2025

Opens in a new windowAmericInn by Wyndham Northfield
Super 8 by Wyndham Jackson MN

Super 8 by Wyndham Jackson MN

2025 Highway 71 N, Jackson, MN
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Nov 21 to Nov 22
$83 total
Nov 21 - Nov 22
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
8/10 Very Good! (593 reviews)
Great place. Friendly service. Would stay again. Walls are a little thin…we heard our neighbors just a little but not a lot. I’m sure they heard our granddaughter too :)

Reviewed on Oct 19, 2025

Opens in a new windowSuper 8 by Wyndham Jackson MN
AmericInn by Wyndham Blue Earth

AmericInn by Wyndham Blue Earth

1495 Domes Dr, Blue Earth, MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $87 total per night from Nov 2 to Nov 3
$87 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a hot tub. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate ...
7.8/10 Good! (451 reviews)
The room was very clean. It had all the accommodations that I needed during my stay. Brandy was amazing Towards me, and help me get Checked in quickly

Reviewed on Aug 13, 2025

Opens in a new windowAmericInn by Wyndham Blue Earth
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $83 total per night from Oct 26 to Oct 27
$83 total
Oct 26 - Oct 27
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
7.8/10 Good! (1,017 reviews)
We would stay again.
Fine. Comfortable. Nothing extra, just fine.

Reviewed on Oct 17, 2025

Opens in a new windowMed City Inn & Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Nov 3 to Nov 4
$151 total
Nov 3 - Nov 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
7.8/10 Good! (1,468 reviews)
Close to Mayo. Convenient

Reviewed on Oct 22, 2025

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
Coratel Inn & Suites By Jasper Northfield

Coratel Inn & Suites By Jasper Northfield

1420 Riverview Dr, Northfield, MN
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $69 total per night from Nov 10 to Nov 11
$69 total
Nov 10 - Nov 11
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
6/10 (636 reviews)
They are working on it
I stayed in their top of the line suite. It was large, well appointed, clean and the bed comfortable. The Jacuzzi bath was broken. I have stayed in this hotel several times and they are improving the cleanliness. Breakfast leaves a great deal to be desired. They put out some slices of Wonder bread ...

Reviewed on Oct 17, 2025

Opens in a new windowCoratel Inn & Suites By Jasper Northfield
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Southern Minnesota Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Southern Minnesota luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Southern Minnesota to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Southern Minnesota will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Southern Minnesota, and plan your next opulent escape.


Southern Minnesota hotels essential information

Accommodation
1,182 hotels
Lowest Price
$69
Highest Price
$151
Popular hotels
Kahler Grand Hotel, AmericInn by Wyndham Blue Earth, Med City Inn & Suites - Mayo Clinic Area, AmericInn by Wyndham Northfield, Super 8 by Wyndham Jackson MN, Coratel Inn & Suites By Jasper Northfield, Kahler Inn and Suites - Mayo Clinic Area, Brentwood Inn & Suites

Popular Luxury Stays in Southern Minnesota

Recent Southern Minnesota Hotel Reviews By Fellow Wanderers

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