Explore Southeast Missouri Spa Hotels & Wellness Resorts
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Southeast Missouri Spa Resorts & Hotels

Drury Inn & Suites Jackson MO

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Hayti Caruthersville

Crown Pointe Lodge, BW Signature Collection

Hampton Inn Farmington

Super 8 by Wyndham Perryville

Eagle Inn Charleston

Super 8 by Wyndham Pevely
Southeast Missouri Spa Hotels
Are you looking for a break from the hustle and bustle of your day-to-day life? Do you want to escape reality and forget about your never ending to-do list? Then why not treat yourself to a relaxing stay at one of the spa hotels in Southeast Missouri? Whether it is for a weekend getaway or a staycation, book your visit to one of the Southeast Missouri luxury spa hotels.
With all of the amazing things to do around Southeast Missouri, you will likely be worn out from sightseeing. The Southeast Missouri spa hotels provide top of the line facilities with hot-tubs, saunas and private treatment rooms. Treat yourself to an indulgent hot stone massage or facial to rejuvenate from a busy day. If that's not enough for you, indulge in a full day-at-the-spa package. And maybe you are just looking to reach maximum relaxation before a fancy night out on the town. Take advantage of the salon features offered at most Southeast Missouri spa hotels and get a mani-pedi before your evening begins.
Travelocity wants to help you relax and rejuvenate during your next stay in Southeast Missouri, but we know that spa treatments can put some strain on your wallet. Bundle your hotel and flight together and save enough to pay for your facial!
Southeast Missouri hotels essential information
Accommodation | 681 hotels |
|---|---|
Lowest Price | $65 |
Highest Price | $115 |
Popular hotels | Crown Pointe Lodge, BW Signature Collection, Drury Inn & Suites Cape Girardeau, Drury Inn & Suites Hayti Caruthersville, Drury Inn & Suites Jackson MO, Drury Inn & Suites Poplar Bluff, Drury Plaza Hotel Cape Girardeau Conference Center, Eagle Inn Charleston, Hampton Inn Farmington, Super 8 by Wyndham Perryville, Super 8 by Wyndham Pevely |
Recent Southeast Missouri hotel reviews by fellow wanderers

Drury Plaza Hotel Cape Girardeau Conference Center
"This Hotel was great, the staff was amazing and the food was good. Breakfast and dinner is free! the room was clean. Bed not soo comfy for but other than that we will definitely stay again."
